serine has been researched along with Arrhythmia in 11 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This Controversies in Research article discusses the hypothesis that protein kinase A (PKA)-mediated phosphorylation of the Ryanodine Receptor (RyR) at a single serine (RyRS2808) is essential for normal sympathetic regulation of cardiac myocyte contractility and is responsible for the disturbed Ca(2+) regulation that underlies depressed contractility in heart failure." | 8.90 | Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias. ( Houser, SR, 2014) |
| "This Controversies in Research article discusses the hypothesis that protein kinase A (PKA)-mediated phosphorylation of the Ryanodine Receptor (RyR) at a single serine (RyRS2808) is essential for normal sympathetic regulation of cardiac myocyte contractility and is responsible for the disturbed Ca(2+) regulation that underlies depressed contractility in heart failure." | 4.90 | Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias. ( Houser, SR, 2014) |
| "Ventricular arrhythmia is the most important risk factor for sudden cardiac death (SCD) after acute myocardial infarction (MI) worldwide." | 1.56 | Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation. ( Chen, G; Du, T; Fang, Q; Wang, DW; Wang, Y; Zhang, Z, 2020) |
| "Nausea and cardiac arrhythmias are lessened, as are the incidence and severity of hypotension." | 1.25 | Levodopa combined with peripheral decarboxylase inhibition in Parkinson's disease. ( Barbeau, A; Botez, MI; Joubert, M; Mars, H, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Z | 1 |
| Fang, Q | 1 |
| Du, T | 1 |
| Chen, G | 1 |
| Wang, Y | 1 |
| Wang, DW | 1 |
| Pollak, AJ | 1 |
| Haghighi, K | 1 |
| Kunduri, S | 1 |
| Arvanitis, DA | 1 |
| Bidwell, PA | 1 |
| Liu, GS | 1 |
| Singh, VP | 1 |
| Gonzalez, DJ | 1 |
| Sanoudou, D | 1 |
| Wiley, SE | 1 |
| Dixon, JE | 1 |
| Kranias, EG | 1 |
| Houser, SR | 2 |
| Herren, AW | 1 |
| Weber, DM | 1 |
| Rigor, RR | 1 |
| Margulies, KB | 1 |
| Phinney, BS | 1 |
| Bers, DM | 1 |
| Currie, S | 1 |
| Zhang, H | 1 |
| Makarewich, CA | 1 |
| Kubo, H | 1 |
| Wang, W | 1 |
| Duran, JM | 1 |
| Li, Y | 1 |
| Berretta, RM | 1 |
| Koch, WJ | 1 |
| Chen, X | 1 |
| Gao, E | 1 |
| Valdivia, HH | 1 |
| Chen, SC | 1 |
| Kennedy, BK | 1 |
| Lampe, PD | 1 |
| Tian, XL | 1 |
| Cheng, Y | 1 |
| Zhang, T | 1 |
| Liao, ML | 1 |
| Yong, SL | 1 |
| Wang, QK | 1 |
| Wang, R | 1 |
| Chen, W | 1 |
| Cai, S | 2 |
| Zhang, J | 1 |
| Bolstad, J | 2 |
| Wagenknecht, T | 2 |
| Liu, Z | 2 |
| Chen, SR | 2 |
| Meng, X | 1 |
| Xiao, B | 1 |
| Huang, X | 1 |
| Li, F | 1 |
| Trujillo, R | 1 |
| Airey, J | 1 |
| Barbeau, A | 1 |
| Mars, H | 1 |
| Botez, MI | 1 |
| Joubert, M | 1 |
2 reviews available for serine and Arrhythmia
| Article | Year |
|---|---|
Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal | 2014 |
Cardiac ryanodine receptor phosphorylation by CaM Kinase II: keeping the balance right.
Topics: Amino Acid Sequence; Animals; Arrhythmias, Cardiac; Binding Sites; Calcium-Binding Proteins; Calcium | 2009 |
9 other studies available for serine and Arrhythmia
| Article | Year |
|---|---|
Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Caveolin 3; Death, Sudden, Cardiac; Male; Mice; Mice, Inbred | 2020 |
Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia.
Topics: Amino Acid Sequence; Animals; Arrhythmias, Cardiac; Calcium-Binding Proteins; Casein Kinase I; Cell | 2017 |
CaMKII Phosphorylation of Na(V)1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure.
Topics: Action Potentials; Amino Acid Sequence; Arrhythmias, Cardiac; Calcium-Calmodulin-Dependent Protein K | 2015 |
Hyperphosphorylation of the cardiac ryanodine receptor at serine 2808 is not involved in cardiac dysfunction after myocardial infarction.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinas | 2012 |
Phosphorylation of connexin43 on S279/282 may contribute to laminopathy-associated conduction defects.
Topics: Animals; Arrhythmias, Cardiac; Biological Transport; Cell Communication; Cell Nucleus; Connexin 43; | 2013 |
Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S.
Topics: Animals; Arrhythmias, Cardiac; Asparagine; Cardiac Complexes, Premature; Long QT Syndrome; Mexiletin | 2007 |
Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Cell Line; Cryoelectron Microscopy; Humans; Mice; | 2007 |
Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor.
Topics: Animals; Antibodies, Monoclonal; Arrhythmias, Cardiac; Calcium-Calmodulin-Dependent Protein Kinase T | 2007 |
Levodopa combined with peripheral decarboxylase inhibition in Parkinson's disease.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Arrhythmias, Cardiac; Benzyl Compounds; D | 1972 |