serine has been researched along with Amyloidosis in 23 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hyperphosphorylated TDP-43 was found within the inclusion bodies in disease lesions; however, the role of hyperphosphorylation and the toxic species are still ambiguous." | 1.72 | Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage. ( Chang, LY; Chen, YR; Chiang, WC; Chou, SC; Fang, YS; Ganesan, K; Huang, SH; Lye, YS; Weng, TY, 2022) |
| "Patients with orthostatic hypotension had low basal plasma norepinephrine levels, which did not increase after postural change." | 1.26 | Orthostatic hypotension in familial amyloid polyneuropathy: treatment with DL-threo-3,4-dihydroxyphenylserine. ( Hayashi, A; Higa, S; Nakajima, A; Sakoda, S; Suzuki, T; Takaba, Y; Yamamura, Y, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (52.17) | 18.7374 |
| 1990's | 4 (17.39) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Chiang, WC | 1 |
| Fang, YS | 1 |
| Lye, YS | 1 |
| Weng, TY | 1 |
| Ganesan, K | 1 |
| Huang, SH | 1 |
| Chang, LY | 1 |
| Chou, SC | 1 |
| Chen, YR | 1 |
| Xing, Y | 1 |
| Andrikopoulos, N | 1 |
| Zhang, Z | 1 |
| Sun, Y | 1 |
| Ke, PC | 1 |
| Ding, F | 1 |
| Maitra, S | 1 |
| Vincent, B | 1 |
| Mangione, PP | 1 |
| Porcari, R | 1 |
| Gillmore, JD | 1 |
| Pucci, P | 1 |
| Monti, M | 1 |
| Porcari, M | 1 |
| Giorgetti, S | 2 |
| Marchese, L | 1 |
| Raimondi, S | 1 |
| Serpell, LC | 1 |
| Chen, W | 1 |
| Relini, A | 1 |
| Marcoux, J | 1 |
| Clatworthy, IR | 1 |
| Taylor, GW | 1 |
| Tennent, GA | 1 |
| Robinson, CV | 1 |
| Hawkins, PN | 1 |
| Stoppini, M | 2 |
| Wood, SP | 1 |
| Pepys, MB | 1 |
| Bellotti, V | 2 |
| Takács, L | 1 |
| Losonczy, G | 1 |
| Matesz, K | 1 |
| Balogh, I | 1 |
| Sohajda, Z | 1 |
| Tóth, K | 1 |
| Fazakas, F | 1 |
| Vereb, G | 1 |
| Berta, A | 1 |
| Suzuki, T | 5 |
| Higa, S | 3 |
| Sakoda, S | 3 |
| Hayashi, A | 4 |
| Yamamura, Y | 2 |
| Takaba, Y | 3 |
| Nakajima, A | 3 |
| Tsuge, I | 1 |
| Ueji, M | 1 |
| Jacobson, DR | 2 |
| Alves, IL | 1 |
| Saraiva, MJ | 1 |
| Thibodeau, SN | 1 |
| Buxbaum, JN | 1 |
| Klein, CJ | 1 |
| Nakumura, M | 1 |
| Lacy, MQ | 1 |
| Benson, MD | 4 |
| Petersen, RC | 1 |
| Connors, LH | 2 |
| Théberge, R | 1 |
| Skare, J | 1 |
| Costello, CE | 1 |
| Falk, RH | 1 |
| Skinner, M | 3 |
| Mangione, P | 1 |
| Sunde, M | 1 |
| Esposito, G | 1 |
| Gianelli, L | 1 |
| Obici, L | 1 |
| Asti, L | 1 |
| Andreola, A | 1 |
| Viglino, P | 1 |
| Merlini, G | 1 |
| Murakami, A | 1 |
| Fujiki, K | 1 |
| Hasegawa, S | 1 |
| Imamura, S | 1 |
| Kawano, H | 1 |
| Kanai, A | 1 |
| Matsumoto, T | 1 |
| Nishi, H | 1 |
| Kimura, A | 1 |
| Harada, H | 1 |
| Hayashi, Y | 1 |
| Nakamura, M | 1 |
| Sasazuki, T | 1 |
| Harats, N | 1 |
| Worth, RM | 1 |
| Nichols, WC | 1 |
| Padilla, LM | 1 |
| Wallace, MR | 1 |
| Yazawa, M | 1 |
| Hanyu, N | 1 |
| Yoshioka, J | 1 |
| Nakadai, A | 1 |
| Yanagisawa, N | 1 |
| Gertz, MA | 1 |
| Cohen, AS | 2 |
| Kyle, RA | 1 |
| Azuma, T | 1 |
| Mizuno, R | 1 |
| Tsujino, S | 1 |
| Kishimoto, S | 1 |
| Mizuta, E | 1 |
| Ichikawa, K | 1 |
4 reviews available for serine and Amyloidosis
| Article | Year |
|---|---|
Cdk5-p25 as a key element linking amyloid and tau pathologies in Alzheimer's disease: Mechanisms and possible therapeutic interventions.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Calpain; Cyclin-Dependent Kinase 5; | 2022 |
[Management of autonomic disorders in amyloidosis].
Topics: Amyloidosis; Catecholamines; Droxidopa; Hereditary Sensory and Autonomic Neuropathies; Humans; Hypot | 1979 |
Genetic amyloidosis: recent advances.
Topics: Alanine; Amyloidosis; DNA Mutational Analysis; Humans; Methionine; Polymorphism, Restriction Fragmen | 1989 |
[Treatment of orthostatic hypotension by noradrenaline supplement].
Topics: Amyloidosis; Aromatic-L-Amino-Acid Decarboxylases; Catecholamines; Droxidopa; Humans; Hypotension, O | 1985 |
19 other studies available for serine and Amyloidosis
| Article | Year |
|---|---|
Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage.
Topics: Amyloid; Amyloidogenic Proteins; Amyloidosis; Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; H | 2022 |
Modulating Nanodroplet Formation En Route to Fibrillization of Amyloid Peptides with Designed Flanking Sequences.
Topics: Amyloid; Amyloid beta-Peptides; Amyloidosis; Glycine; Humans; Nanostructures; Serine | 2022 |
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Crystallography, X-Ray; Humans; Hydrogen Bonding; Molecul | 2014 |
TGFBI (BIGH3) gene mutations in Hungary--report of the novel F547S mutation associated with polymorphic corneal amyloidosis.
Topics: Amino Acid Substitution; Amyloidosis; Base Sequence; Cornea; Corneal Dystrophies, Hereditary; Extrac | 2007 |
Orthostatic hypotension in familial amyloid polyneuropathy: treatment with DL-threo-3,4-dihydroxyphenylserine.
Topics: Adult; Amyloidosis; Blood Pressure; Droxidopa; Female; Humans; Hypotension, Orthostatic; Male; Middl | 1981 |
Effect of infused L-threo-3,4-dihydroxyphenylserine on adrenergic activity in patients with familial amyloid polyneuropathy.
Topics: Adult; Amyloidosis; Autonomic Nervous System; Blood Pressure; Dopamine beta-Hydroxylase; Droxidopa; | 1980 |
Pharmacokinetic studies of oral L-threo-3,4-dihydroxyphenylserine in normal subjects and patients with familial amyloid polyneuropathy.
Topics: Adult; Amyloidosis; Blood Pressure; Dopamine beta-Hydroxylase; Droxidopa; Female; Humans; Intestinal | 1982 |
Transthyretin Ser 6 gene frequency in individuals without amyloidosis.
Topics: Amyloidosis; Founder Effect; Gene Frequency; Glycine; Humans; Point Mutation; Polymorphism, Genetic; | 1995 |
Transthyretin amyloidosis (serine 44) with headache, hearing loss, and peripheral neuropathy.
Topics: Adult; Amino Acid Sequence; Amyloidosis; Base Sequence; Exons; Headache; Hearing Loss, Sensorineural | 1998 |
A new transthyretin variant (Ser23Asn) associated with familial amyloidosis in a Portuguese patient.
Topics: Adult; Amino Acid Substitution; Amyloidosis; Asparagine; Chromatography, High Pressure Liquid; Human | 1999 |
Amyloid fibrils derived from the apolipoprotein A1 Leu174Ser variant contain elements of ordered helical structure.
Topics: Amino Acid Substitution; Amyloidosis; Apolipoprotein A-I; Humans; Leucine; Magnetic Resonance Spectr | 2001 |
Transthyretin Ser-44 mutation in a case with vitreous amyloidosis.
Topics: Adult; Amino Acid Substitution; Amyloidosis; DNA Mutational Analysis; Eye Diseases; Female; Humans; | 2002 |
Novel variant transthyretin gene (Ser50 to Ile) in familial cardiac amyloidosis.
Topics: Amyloidosis; Base Sequence; Cardiomyopathies; Cloning, Molecular; DNA; Electrophoresis, Polyacrylami | 1992 |
Hereditary amyloidosis: evidence against early amyloid deposition.
Topics: Adult; Amyloid; Amyloidosis; Carpal Bones; DNA; Female; Humans; Ligaments; Male; Nucleic Acid Hybrid | 1989 |
Prenatal detection of a gene for hereditary amyloidosis.
Topics: Amyloidosis; Blotting, Southern; Exons; Female; Fetal Diseases; Genes; Humans; Polymerase Chain Reac | 1989 |
[Bullous lesions in familial amyloid polyneuropathy and treatment with L-threo-3,4-dihydroxyphenylserine--with reference to peripheral circulation response against direct heat stimulation].
Topics: Adult; Amyloidosis; Droxidopa; Female; Hot Temperature; Humans; Male; Middle Aged; Peripheral Nervou | 1988 |
Isolation and characterization of a kappa amyloid fibril protein.
Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Animals; Antibody Formation; Electrophoresis, Polyacrylam | 1985 |
Studies of neurocirculatory effects of long-term L-threo-3,4-dihydroxyphenylserine administration in a patient with familial amyloidotic polyneuropathy.
Topics: Amyloidosis; Blood Circulation; Blood Pressure; Consciousness; Droxidopa; Female; Heart Rate; Humans | 1988 |
N-terminal amino acid analysis of the amyloid fibril protein.
Topics: Amino Acids; Amyloid; Amyloidosis; Aspartic Acid; Chromatography, Paper; Electrophoresis; Fluorine; | 1971 |