serine has been researched along with Amyloid Deposits in 8 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperhomocysteinemia (HHcy) has been recognized as a risk factor for developing Alzheimer's disease (AD)." | 7.76 | Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease. ( Gould, TJ; Kruger, WD; Portugal, GS; Pratico, D; Wang, H; Zhuo, JM, 2010) |
| "Hyperhomocysteinemia (HHcy) has been recognized as a risk factor for developing Alzheimer's disease (AD)." | 3.76 | Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease. ( Gould, TJ; Kruger, WD; Portugal, GS; Pratico, D; Wang, H; Zhuo, JM, 2010) |
| "LPL immunostains senile plaques, and is a ligand of the low-density lipoprotein receptor-related protein (LRP), a major apolipoprotein E (apoE) receptor." | 1.31 | Lack of association of two lipoprotein lipase polymorphisms with Alzheimer's disease. ( Cho, HS; Martin-Rehrmann, MD; Rebeck, GW, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Folorunso, OO | 1 |
| Harvey, TL | 1 |
| Brown, SE | 1 |
| Chelini, G | 1 |
| Berretta, S | 1 |
| Balu, DT | 1 |
| Wang, ZH | 1 |
| Liu, P | 1 |
| Liu, X | 1 |
| Manfredsson, FP | 1 |
| Sandoval, IM | 1 |
| Yu, SP | 1 |
| Wang, JZ | 1 |
| Ye, K | 1 |
| Zhuo, JM | 1 |
| Portugal, GS | 1 |
| Kruger, WD | 1 |
| Wang, H | 1 |
| Gould, TJ | 1 |
| Pratico, D | 1 |
| Martin-Rehrmann, MD | 1 |
| Cho, HS | 1 |
| Rebeck, GW | 1 |
| Kubo, T | 2 |
| Nishimura, S | 1 |
| Kumagae, Y | 1 |
| Kaneko, I | 2 |
| Miklossy, J | 1 |
| Taddei, K | 1 |
| Suva, D | 1 |
| Verdile, G | 1 |
| Fonte, J | 1 |
| Fisher, C | 1 |
| Gnjec, A | 1 |
| Ghika, J | 1 |
| Suard, F | 1 |
| Mehta, PD | 1 |
| McLean, CA | 1 |
| Masters, CL | 1 |
| Brooks, WS | 1 |
| Martins, RN | 1 |
| Obi, K | 1 |
| Akiyama, H | 1 |
| Kondo, H | 1 |
| Shimomura, Y | 1 |
| Hasegawa, M | 1 |
| Iwatsubo, T | 1 |
| Mizuno, Y | 1 |
| Mochizuki, H | 1 |
| Morimoto, K | 1 |
8 other studies available for serine and Amyloid Deposits
| Article | Year |
|---|---|
The D-serine biosynthetic enzyme serine racemase is expressed by reactive astrocytes in the amygdala of human and a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amygdala; Animals; Astrocytes; Disease Models, Animal; Humans; Mice; Plaque, Amyl | 2023 |
Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Behavior, Animal; Brain; Cognition | 2017 |
Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Brain; CHO Cells; Cricetinae | 2010 |
Lack of association of two lipoprotein lipase polymorphisms with Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Apolipoproteins E; Asparagine; Brain; Brain Chemistry; DNA M | 2002 |
In vivo conversion of racemized beta-amyloid ([D-Ser 26]A beta 1-40) to truncated and toxic fragments ([D-Ser 26]A beta 25-35/40) and fragment presence in the brains of Alzheimer's patients.
Topics: Aged; Aging; Alzheimer Disease; Amino Acid Isomerases; Amyloid beta-Peptides; Animals; Astrocytes; B | 2002 |
Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease.
Topics: Adult; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Blotting, Western; Brain; | 2003 |
Relationship of phosphorylated alpha-synuclein and tau accumulation to Abeta deposition in the cerebral cortex of dementia with Lewy bodies.
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Amyloid beta-Peptides; Analysis of Variance; Cerebral Cort | 2008 |
Drastic neuronal loss in vivo by beta-amyloid racemized at Ser(26) residue: conversion of non-toxic [D-Ser(26)]beta-amyloid 1-40 to toxic and proteinase-resistant fragments.
Topics: Alzheimer Disease; Amino Acid Isomerases; Amino Acid Sequence; Aminopeptidases; Amyloid beta-Peptide | 2001 |