serine has been researched along with Amentia in 21 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Frontotemporal dementia with parkinsonism linked to chromosome 17q21-22 (FTDP-17) is an autosomal dominant tauopathy manifested by a variable combination of personality changes, cognitive decline and hypokinetic-rigid movement disorder." | 1.32 | Frontotemporal dementia and parkinsonism with the P301S tau gene mutation in a Jewish family. ( Abramsky, O; Biran, I; Boher, M; Ekstein, D; Gal, A; Gomori, JM; Lossos, A; Meiner, Z; Newman, JP; Reches, A; Rosenmann, H; Soffer, D, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 16 (76.19) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashby, EL | 1 |
| Miners, JS | 1 |
| Kumar, S | 1 |
| Walter, J | 1 |
| Love, S | 1 |
| Kehoe, PG | 1 |
| Biemans, EA | 1 |
| Verhoeven-Duif, NM | 1 |
| Gerrits, J | 1 |
| Claassen, JA | 1 |
| Kuiperij, HB | 1 |
| Verbeek, MM | 1 |
| Inukai, Y | 1 |
| Nonaka, T | 2 |
| Arai, T | 2 |
| Yoshida, M | 1 |
| Hashizume, Y | 1 |
| Beach, TG | 1 |
| Buratti, E | 1 |
| Baralle, FE | 1 |
| Akiyama, H | 2 |
| Hisanaga, S | 1 |
| Hasegawa, M | 2 |
| Nesgaard, L | 1 |
| Vad, B | 1 |
| Christiansen, G | 1 |
| Otzen, D | 1 |
| Kametani, F | 1 |
| Suzuki, T | 1 |
| Dohmae, N | 1 |
| Lossos, A | 1 |
| Reches, A | 1 |
| Gal, A | 1 |
| Newman, JP | 1 |
| Soffer, D | 1 |
| Gomori, JM | 1 |
| Boher, M | 1 |
| Ekstein, D | 1 |
| Biran, I | 1 |
| Meiner, Z | 1 |
| Abramsky, O | 1 |
| Rosenmann, H | 1 |
| Kobayashi, K | 2 |
| Kidani, T | 2 |
| Ujike, H | 2 |
| Hayashi, M | 2 |
| Ishihara, T | 2 |
| Miyazu, K | 1 |
| Kuroda, S | 2 |
| Koshino, Y | 2 |
| Iijima, M | 1 |
| Nakano, H | 1 |
| Sugimori, K | 1 |
| Shimazaki, M | 1 |
| Alonso, Adel C | 1 |
| Mederlyova, A | 1 |
| Novak, M | 1 |
| Grundke-Iqbal, I | 1 |
| Iqbal, K | 1 |
| Belorgey, D | 1 |
| Sharp, LK | 1 |
| Crowther, DC | 1 |
| Onda, M | 1 |
| Johansson, J | 1 |
| Lomas, DA | 2 |
| Pérez, M | 2 |
| Ribe, E | 1 |
| Rubio, A | 1 |
| Lim, F | 2 |
| Morán, MA | 1 |
| Ramos, PG | 1 |
| Ferrer, I | 1 |
| Isla, MT | 1 |
| Avila, J | 2 |
| Saunders-Pullman, R | 1 |
| Lipton, RB | 1 |
| Senthil, G | 1 |
| Katz, M | 1 |
| Costan-Toth, C | 1 |
| Derby, C | 1 |
| Bressman, S | 1 |
| Verghese, J | 1 |
| Ozelius, LJ | 1 |
| Dächsel, JC | 1 |
| Ross, OA | 1 |
| Mata, IF | 1 |
| Kachergus, J | 1 |
| Toft, M | 1 |
| Cannon, A | 1 |
| Baker, M | 1 |
| Adamson, J | 1 |
| Hutton, M | 1 |
| Dickson, DW | 1 |
| Farrer, MJ | 1 |
| Spina, S | 1 |
| Murrell, JR | 1 |
| Yoshida, H | 1 |
| Ghetti, B | 1 |
| Bermingham, N | 1 |
| Sweeney, B | 1 |
| Dlouhy, SR | 1 |
| Crowther, RA | 1 |
| Goedert, M | 1 |
| Keohane, C | 1 |
| van Swieten, JC | 1 |
| Bronner, IF | 1 |
| Azmani, A | 1 |
| Severijnen, LA | 1 |
| Kamphorst, W | 1 |
| Ravid, R | 1 |
| Rizzu, P | 1 |
| Willemsen, R | 1 |
| Heutink, P | 1 |
| Gaig, C | 1 |
| Ezquerra, M | 1 |
| Martí, MJ | 1 |
| Valldeoriola, F | 1 |
| Muñoz, E | 1 |
| Lladó, A | 1 |
| Rey, MJ | 1 |
| Cardozo, A | 1 |
| Molinuevo, JL | 1 |
| Tolosa, E | 1 |
| Van Deerlin, VM | 1 |
| Leverenz, JB | 1 |
| Bekris, LM | 1 |
| Bird, TD | 1 |
| Yuan, W | 1 |
| Elman, LB | 1 |
| Clay, D | 1 |
| Wood, EM | 1 |
| Chen-Plotkin, AS | 1 |
| Martinez-Lage, M | 1 |
| Steinbart, E | 1 |
| McCluskey, L | 1 |
| Grossman, M | 1 |
| Neumann, M | 1 |
| Wu, IL | 1 |
| Yang, WS | 1 |
| Kalb, R | 1 |
| Galasko, DR | 1 |
| Montine, TJ | 1 |
| Trojanowski, JQ | 2 |
| Lee, VM | 2 |
| Schellenberg, GD | 1 |
| Yu, CE | 1 |
| Mawal-Dewan, M | 1 |
| Schmidt, ML | 1 |
| Balin, B | 1 |
| Perl, DP | 1 |
| Davis, RL | 1 |
| Shrimpton, AE | 1 |
| Holohan, PD | 1 |
| Bradshaw, C | 1 |
| Feiglin, D | 1 |
| Collins, GH | 1 |
| Sonderegger, P | 1 |
| Kinter, J | 1 |
| Becker, LM | 1 |
| Lacbawan, F | 1 |
| Krasnewich, D | 1 |
| Muenke, M | 1 |
| Lawrence, DA | 1 |
| Yerby, MS | 1 |
| Shaw, CM | 1 |
| Gooptu, B | 1 |
| Elliott, PR | 1 |
| Finch, JT | 1 |
| Carrell, RW | 1 |
| Arrasate, M | 1 |
| Komiya, T | 1 |
| Narabayashi, H | 1 |
| Kondo, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Genetic Disease Gene Identification[NCT00916903] | 200 participants (Anticipated) | Observational | 2005-10-31 | Enrolling by invitation | |||
| Clinical, Molecular and Biochemical Characterization of Familial Encephalopathy With Neuroserpin Inclusion Bodies[NCT00006176] | 100 participants | Observational | 2000-08-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 other studies available for serine and Amentia
| Article | Year |
|---|---|
Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Dementia; Deme | 2015 |
CSF d-serine concentrations are similar in Alzheimer's disease, other dementias, and elderly controls.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; | 2016 |
Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Antibodies, Monoclonal; Brain; Dementia; DNA-Binding Protein | 2008 |
Kinetic partitioning between aggregation and vesicle permeabilization by modified ADan.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amyloid; Circular Dichroism; Cysteine; De | 2009 |
Identification of casein kinase-1 phosphorylation sites on TDP-43.
Topics: Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Brain; Casein Kinase I; Dementia; DNA-Binding Pr | 2009 |
Frontotemporal dementia and parkinsonism with the P301S tau gene mutation in a Jewish family.
Topics: Adult; Algeria; Cerebral Cortex; Dementia; DNA Mutational Analysis; Family Health; Female; Humans; I | 2003 |
Another phenotype of frontotemporal dementia and parkinsonism linked to chromosome-17 (FTDP-17) with a missense mutation of S305N closely resembling Pick's disease.
Topics: Asparagine; Chromosomes, Human, Pair 17; Dementia; Dentate Gyrus; Genetic Linkage; Humans; Immunohis | 2003 |
Pick's disease pathology of a missense mutation of S305N of frontotemporal dementia and parkinsonism linked to chromosome 17: another phenotype of S305N.
Topics: Asparagine; Base Sequence; Brain; Dementia; DNA Mutational Analysis; Genetic Linkage; Heterozygote; | 2004 |
Promotion of hyperphosphorylation by frontotemporal dementia tau mutations.
Topics: Brain; Chromosomes, Human, Pair 17; Dementia; DNA; Electrophoresis, Polyacrylamide Gel; Humans; Immu | 2004 |
Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB.
Topics: Amino Acid Substitution; Arginine; Biopolymers; Catalysis; Circular Dichroism; Dementia; Epilepsy; H | 2004 |
Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Chromosomes, Human, Pair 17; | 2005 |
Increased frequency of the LRRK2 G2019S mutation in an elderly Ashkenazi Jewish population is not associated with dementia.
Topics: Aged, 80 and over; Aging; Dementia; DNA Mutational Analysis; Female; Glycine; Humans; Jews; Leucine- | 2006 |
Lrrk2 G2019S substitution in frontotemporal lobar degeneration with ubiquitin-immunoreactive neuronal inclusions.
Topics: Aged; Amino Acid Substitution; Dementia; Female; Glycine; Humans; Inclusion Bodies; Leucine-Rich Rep | 2007 |
The novel Tau mutation G335S: clinical, neuropathological and molecular characterization.
Topics: Adult; Dementia; DNA Mutational Analysis; Glycine; Humans; Male; Microscopy, Electron, Transmission; | 2007 |
The DeltaK280 mutation in MAP tau favors exon 10 skipping in vivo.
Topics: Alzheimer Disease; Blotting, Western; Brain; Dementia; Exons; Female; Humans; Immunohistochemistry; | 2007 |
Screening for the LRRK2 G2019S and codon-1441 mutations in a pathological series of parkinsonian syndromes and frontotemporal lobar degeneration.
Topics: Dementia; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Glyci | 2008 |
TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Amyotrophic Lateral Sclerosis; Brain; Child; De | 2008 |
Identification of phosphorylation sites in PHF-TAU from patients with Guam amyotrophic lateral sclerosis/parkinsonism-dementia complex.
Topics: Aged; Amyotrophic Lateral Sclerosis; Binding Sites, Antibody; Blotting, Western; Brain Chemistry; De | 1996 |
Familial dementia caused by polymerization of mutant neuroserpin.
Topics: Biopolymers; Cerebral Cortex; Dementia; Female; Humans; Inclusion Bodies; Male; Neuropeptides; Neuro | 1999 |
Familial dementia caused by polymerization of mutant neuroserpin.
Topics: Biopolymers; Cerebral Cortex; Dementia; Female; Humans; Inclusion Bodies; Male; Neuropeptides; Neuro | 1999 |
Familial dementia caused by polymerization of mutant neuroserpin.
Topics: Biopolymers; Cerebral Cortex; Dementia; Female; Humans; Inclusion Bodies; Male; Neuropeptides; Neuro | 1999 |
Familial dementia caused by polymerization of mutant neuroserpin.
Topics: Biopolymers; Cerebral Cortex; Dementia; Female; Humans; Inclusion Bodies; Male; Neuropeptides; Neuro | 1999 |
The FTDP-17-linked mutation R406W abolishes the interaction of phosphorylated tau with microtubules.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Chromosomes, Human, Pai | 2000 |
[The effective of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS) in hypersomnia and subcortical dementia caused by bilateral medial thalamic and midbrain infarcts].
Topics: Aged; Cerebral Infarction; Dementia; Disorders of Excessive Somnolence; Droxidopa; Female; Humans; M | 1988 |