serine has been researched along with Alagille Syndrome in 2 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Alagille Syndrome: A multisystem disorder that is characterized by aplasia of intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC), and malformations in the cardiovascular system, the eyes, the vertebral column, and the facies. Major clinical features include JAUNDICE, and congenital heart disease with peripheral PULMONARY STENOSIS. Alagille syndrome may result from heterogeneous gene mutations, including mutations in JAG1 on CHROMOSOME 20 (Type 1) and NOTCH2 on CHROMOSOME 1 (Type 2).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luca, VC | 1 |
| Jude, KM | 1 |
| Pierce, NW | 1 |
| Nachury, MV | 1 |
| Fischer, S | 1 |
| Garcia, KC | 1 |
| Morrissette, JD | 1 |
| Colliton, RP | 1 |
| Spinner, NB | 1 |
2 other studies available for serine and Alagille Syndrome
| Article | Year |
|---|---|
Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Topics: Alagille Syndrome; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Conserved Seque | 2015 |
Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome.
Topics: 3T3 Cells; Alagille Syndrome; Amino Acid Substitution; Animals; Arginine; Biological Transport, Acti | 2001 |