serine has been researched along with Aggressive Periodontitis in 3 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Aggressive Periodontitis: Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Periodontitis is a multifactorial disease in which environmental and genetic determinant factors contribute to individual subjects susceptibility." | 1.35 | E-selectin and L-selectin polymorphisms in patients with periodontitis. ( Gholami, L; Hajilooi, M; Houshmand, B; Mani-Kashani, K; Rafiei, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Houshmand, B | 1 |
| Rafiei, A | 1 |
| Hajilooi, M | 1 |
| Mani-Kashani, K | 1 |
| Gholami, L | 1 |
| Yagi, M | 1 |
| Kantarci, A | 1 |
| Iwata, T | 1 |
| Omori, K | 1 |
| Ayilavarapu, S | 1 |
| Ito, K | 1 |
| Hasturk, H | 1 |
| Van Dyke, TE | 1 |
| Noack, B | 1 |
| Görgens, H | 1 |
| Hoffmann, T | 1 |
| Fanghänel, J | 1 |
| Kocher, T | 1 |
| Eickholz, P | 1 |
| Schackert, HK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Observational Study on Cytokine Production by Leukocytes of Papillon-Lefèvre Syndrome Patients and Healthy Probands in Whole Blood Cultures[NCT01116934] | 17 participants (Actual) | Observational | 2006-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Concentrations of IL-8, IL-6, IP-10, interferon (IFN)-gamma, and IL-1 beta, in plasma/RPMI samples were determined by enzyme linked immunosorbent assay (ELISA) according to the manufacturers' instructions (NCT01116934)
Timeframe: 2006
| Intervention | pg/ml (Median) | ||||
|---|---|---|---|---|---|
| interleukin-1 beta | interleukin-6 | interferon-inducible protein-10 | interferon gamma | interleukin-8 | |
| Healthy Controls | 896.21 | 45734 | 11563 | 3317.4 | 44390 |
| Papillon-Lefèvre Syndrome (PLS) Patients | 1100.00 | 65559 | 12902.5 | 3704.5 | 50520 |
3 other studies available for serine and Aggressive Periodontitis
| Article | Year |
|---|---|
E-selectin and L-selectin polymorphisms in patients with periodontitis.
Topics: Adenine; Adolescent; Adult; Aggressive Periodontitis; Alleles; Arginine; Chronic Periodontitis; Cyto | 2009 |
PDK1 regulates chemotaxis in human neutrophils.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Aggressive Periodontitis; Blotting, Western; Cells, Cu | 2009 |
Novel mutations in the cathepsin C gene in patients with pre-pubertal aggressive periodontitis and Papillon-Lefèvre syndrome.
Topics: Adolescent; Aggressive Periodontitis; Alleles; Amino Acid Sequence; Arginine; Cathepsin C; Child; Co | 2004 |