Page last updated: 2024-11-08

serine and Age-Related Osteoporosis

serine has been researched along with Age-Related Osteoporosis in 8 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Osteoporosis is a common disease of the elderly that affects millions of patients worldwide."5.91Enhanced efficiency of calcium-derived oleoyl serine on osteoporosis via Wnt/β-catenin pathway. ( Cao, W; Chen, Y; Dong, J; Hao, M; Hu, X; Jin, C; Ke, C; Liu, B; Peng, Z; Weng, H; Zhang, Z; Zhong, J, 2023)
"Fisetin is a bioactive flavonol that inhibits osteoclastogenesis and promotes osteoblastogenesis."5.62Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis. ( Choi, YH; Kang, CH; Kim, GY; Lee, CM; Lee, MH; Lee, S; Molagoda, IMN, 2021)
"Osteoporosis is a common disease of the elderly that affects millions of patients worldwide."1.91Enhanced efficiency of calcium-derived oleoyl serine on osteoporosis via Wnt/β-catenin pathway. ( Cao, W; Chen, Y; Dong, J; Hao, M; Hu, X; Jin, C; Ke, C; Liu, B; Peng, Z; Weng, H; Zhang, Z; Zhong, J, 2023)
"Fisetin is a bioactive flavonol that inhibits osteoclastogenesis and promotes osteoblastogenesis."1.62Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis. ( Choi, YH; Kang, CH; Kim, GY; Lee, CM; Lee, MH; Lee, S; Molagoda, IMN, 2021)
"Rates of osteoporosis are significantly lower in regions of the world where olive oil consumption is a dietary cornerstone."1.43Levels of bioactive lipids in cooking oils: olive oil is the richest source of oleoyl serine. ( Bradshaw, HB; Leishman, E, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Chen, Y1
Ke, C1
Zhong, J1
Cao, W1
Hu, X1
Hao, M1
Dong, J1
Zhang, Z1
Weng, H1
Liu, B1
Jin, C1
Peng, Z1
Baraghithy, S1
Smoum, R2
Attar-Namdar, M2
Mechoulam, R2
Bab, I2
Tam, J2
Molagoda, IMN1
Kang, CH1
Lee, MH1
Choi, YH1
Lee, CM1
Lee, S1
Kim, GY1
Bradshaw, HB2
Leishman, E1
Tian, W1
Fu, Y1
Garcia-Elias, A1
Fernández-Fernández, JM1
Vicente, R1
Kramer, PL1
Klein, RF1
Hitzemann, R1
Orwoll, ES1
Wilmot, B1
McWeeney, S1
Valverde, MA1
Cohen, DM1
Bar, A1
Tan, B1
Milman, G1
Ofek, O1
Stuart, JM1
Bajayo, A1
Kram, V1
O'Dell, D1
Walker, MJ1
Bahtiar, A1
Nakamura, T1
Kishida, K1
Katsura, J1
Nitta, M1
Ishida-Kitagawa, N1
Ogawa, T1
Takeya, T1
Larbre, F1
Hartemann, E1
Guibaud, P1
Collombel, C1
Guerrier, G1

Other Studies

8 other studies available for serine and Age-Related Osteoporosis

ArticleYear
Enhanced efficiency of calcium-derived oleoyl serine on osteoporosis via Wnt/β-catenin pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 160

    Topics: Aged; beta Catenin; Calcium; Cell Differentiation; Humans; Osteogenesis; Osteoporosis; Quality of Li

2023
HU-671, a Novel Oleoyl Serine Derivative, Exhibits Enhanced Efficacy in Reversing Ovariectomy-Induced Osteoporosis and Bone Marrow Adiposity.
    Molecules (Basel, Switzerland), 2019, Oct-16, Volume: 24, Issue:20

    Topics: Adipocytes; Adiposity; Animals; Bone Marrow; Disease Models, Animal; Female; Mice; Oleic Acids; Oste

2019
Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis.
    Biochemical pharmacology, 2021, Volume: 192

    Topics: Animals; Animals, Genetically Modified; beta Catenin; Cell Differentiation; Cell Line; Dose-Response

2021
Levels of bioactive lipids in cooking oils: olive oil is the richest source of oleoyl serine.
    Journal of basic and clinical physiology and pharmacology, 2016, May-01, Volume: 27, Issue:3

    Topics: Animals; Cooking; Diet; Lipids; Olive Oil; Osteoporosis; Plant Oils; Rapeseed Oil; Rats; Rats, Wista

2016
A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Aug-18, Volume: 106, Issue:33

    Topics: Aged; Alleles; Animals; Cohort Studies; Humans; Hyponatremia; Male; Mice; Mutation; Osteoporosis; Po

2009
Oleoyl serine, an endogenous N-acyl amide, modulates bone remodeling and mass.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Oct-12, Volume: 107, Issue:41

    Topics: Amides; Analysis of Variance; Animals; Blotting, Western; Bone Density; Bone Remodeling; Cell Line;

2010
The l-Ser analog #290 promotes bone recovery in OP and RA mice.
    Pharmacological research, 2011, Volume: 64, Issue:3

    Topics: 3T3 Cells; Animals; Arthritis, Rheumatoid; Bone and Bones; Bone Resorption; Cell Differentiation; Ce

2011
[Glycinosis with acidocetosis of late revelation and favorable evolution].
    Archives francaises de pediatrie, 1970, Volume: 27, Issue:5

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Glutamates; Gl

1970