serine has been researched along with Age-Related Memory Disorders in 19 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A common nonsynonymous single nucleotide polymorphism leading to a serine-to-cysteine substitution at amino acid 704 (Ser(704)Cys) in the DISC1 protein sequence has been recently associated with schizophrenia and with specific hippocampal abnormalities." | 3.74 | Association of the SerCys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding. ( Bertolino, A; Blasi, G; Caforio, G; Callicott, JH; Di Giorgio, A; Gambi, F; Kolachana, B; Latorre, V; Nardini, M; Papazacharias, A; Popolizio, T; Rampino, A; Rizzo, M; Romano, R; Sambataro, F; Weinberger, DR, 2008) |
| "The aim of study was to investigate the effects of pyrroloquinoline quinone (PQQ) combined with d-serine on the modulation of glycine sites in the brain of rats using social recognition test." | 1.43 | Modulation of glycine sites enhances social memory in rats using PQQ combined with d-serine. ( Liu, D; Mao, S; Peng, Y; Qin, X; Zhang, R; Zhou, X, 2016) |
| "Thus, NE stimulation may prevent memory loss in Ts65Dn mice, and may hold promise for treatment in individuals with DS and dementia." | 1.42 | Designer receptors enhance memory in a mouse model of Down syndrome. ( Aston-Jones, G; Boger, HA; Cass, WA; Fortress, AM; Granholm, AC; Hamlett, ED; Vazey, EM, 2015) |
| "Binge drinking is common in adolescents, but the impact of only a few binges on learning and memory appears underestimated." | 1.42 | Two Binges of Ethanol a Day Keep the Memory Away in Adolescent Rats: Key Role for GLUN2B Subunit. ( Alaux-Cantin, S; Antol, J; Bennouar, KE; Kervern, M; Naassila, M; Pierrefiche, O; Rabiant, K; Robert, A; Silvestre de Ferron, B, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 1 |
| Tanokashira, D | 1 |
| Fukui, Y | 1 |
| Maruyama, M | 1 |
| Kuroiwa, C | 1 |
| Saito, T | 1 |
| Saido, TC | 1 |
| Taguchi, A | 1 |
| Aquilani, R | 1 |
| Costa, A | 1 |
| Maestri, R | 1 |
| Cotta Ramusino, M | 1 |
| Pierobon, A | 1 |
| Dossena, M | 1 |
| Solerte, SB | 1 |
| Condino, AM | 1 |
| Torlaschi, V | 1 |
| Bini, P | 1 |
| Boselli, M | 1 |
| Ceroni, M | 1 |
| Buonocore, D | 1 |
| Boschi, F | 1 |
| Bruni, M | 1 |
| Verri, M | 1 |
| Torres, AK | 1 |
| Jara, C | 1 |
| Olesen, MA | 1 |
| Tapia-Rojas, C | 1 |
| Jia, N | 1 |
| Han, K | 1 |
| Kong, JJ | 1 |
| Zhang, XM | 1 |
| Sha, S | 1 |
| Ren, GR | 1 |
| Cao, YP | 1 |
| Kanno, T | 1 |
| Tsuchiya, A | 1 |
| Nishizaki, T | 1 |
| Fortress, AM | 1 |
| Hamlett, ED | 1 |
| Vazey, EM | 1 |
| Aston-Jones, G | 1 |
| Cass, WA | 1 |
| Boger, HA | 1 |
| Granholm, AC | 1 |
| Silvestre de Ferron, B | 1 |
| Bennouar, KE | 1 |
| Kervern, M | 1 |
| Alaux-Cantin, S | 1 |
| Robert, A | 1 |
| Rabiant, K | 1 |
| Antol, J | 1 |
| Naassila, M | 1 |
| Pierrefiche, O | 1 |
| Ren, QG | 1 |
| Wang, YJ | 1 |
| Gong, WG | 1 |
| Xu, L | 1 |
| Zhang, ZJ | 1 |
| Zhou, X | 1 |
| Liu, D | 1 |
| Zhang, R | 1 |
| Peng, Y | 1 |
| Qin, X | 1 |
| Mao, S | 1 |
| McQuail, JA | 1 |
| Beas, BS | 1 |
| Kelly, KB | 1 |
| Simpson, KL | 1 |
| Frazier, CJ | 1 |
| Setlow, B | 1 |
| Bizon, JL | 1 |
| Sunyer, B | 1 |
| Shim, KS | 1 |
| An, G | 1 |
| Höger, H | 1 |
| Lubec, G | 1 |
| Di Giorgio, A | 1 |
| Blasi, G | 1 |
| Sambataro, F | 1 |
| Rampino, A | 1 |
| Papazacharias, A | 1 |
| Gambi, F | 1 |
| Romano, R | 1 |
| Caforio, G | 1 |
| Rizzo, M | 1 |
| Latorre, V | 1 |
| Popolizio, T | 1 |
| Kolachana, B | 1 |
| Callicott, JH | 1 |
| Nardini, M | 1 |
| Weinberger, DR | 1 |
| Bertolino, A | 1 |
| DeVito, LM | 1 |
| Balu, DT | 1 |
| Kanter, BR | 1 |
| Lykken, C | 1 |
| Basu, AC | 1 |
| Coyle, JT | 1 |
| Eichenbaum, H | 1 |
| Lim, Y | 1 |
| Kehm, VM | 1 |
| Lee, EB | 1 |
| Soper, JH | 1 |
| Li, C | 1 |
| Trojanowski, JQ | 1 |
| Lee, VM | 1 |
| Liu, SJ | 1 |
| Zhang, AH | 1 |
| Li, HL | 1 |
| Wang, Q | 1 |
| Deng, HM | 1 |
| Netzer, WJ | 1 |
| Xu, H | 1 |
| Wang, JZ | 1 |
| Andersen, JD | 1 |
| Pouzet, B | 1 |
| Mansuy, IM | 1 |
| Shenolikar, S | 1 |
| Keays, DA | 1 |
| Tian, G | 1 |
| Poirier, K | 1 |
| Huang, GJ | 1 |
| Siebold, C | 1 |
| Cleak, J | 1 |
| Oliver, PL | 1 |
| Fray, M | 1 |
| Harvey, RJ | 1 |
| Molnár, Z | 1 |
| Piñon, MC | 1 |
| Dear, N | 1 |
| Valdar, W | 1 |
| Brown, SD | 1 |
| Davies, KE | 1 |
| Rawlins, JN | 1 |
| Cowan, NJ | 1 |
| Nolan, P | 1 |
| Chelly, J | 1 |
| Flint, J | 1 |
| Langlais, PJ | 1 |
| Mair, RG | 1 |
| Whalen, PJ | 1 |
| McCourt, W | 1 |
| McEntee, WJ | 1 |
1 review available for serine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Protein serine/threonine phosphatases in neuronal plasticity and disorders of learning and memory.
Topics: Animals; Brain; Humans; Learning Disabilities; Memory Disorders; Neuronal Plasticity; Phosphoprotein | 2006 |
1 trial available for serine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Memory effect of DL-threo-3,4-dihydroxyphenylserine (DOPS) in human Korsakoff's disease.
Topics: Alcohol Amnestic Disorder; Droxidopa; Hemodynamics; Humans; Male; Memory Disorders; Middle Aged; Psy | 1988 |
17 other studies available for serine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Serine Phosphorylation of IRS1 Correlates with Aβ-Unrelated Memory Deficits and Elevation in Aβ Level Prior to the Onset of Memory Decline in AD.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Dia | 2019 |
Mini Nutritional Assessment May Identify a Dual Pattern of Perturbed Plasma Amino Acids in Patients with Alzheimer's Disease: A Window to Metabolic and Physical Rehabilitation?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Attention; Female; Histidine; Humans; Male; | 2020 |
Pathologically phosphorylated tau at S396/404 (PHF-1) is accumulated inside of hippocampal synaptic mitochondria of aged Wild-type mice.
Topics: Aging; Animals; Cognitive Dysfunction; Hippocampus; Memory Disorders; Mice; Mice, Inbred C57BL; Mito | 2021 |
(-)-Epigallocatechin-3-gallate alleviates spatial memory impairment in APP/PS1 mice by restoring IRS-1 signaling defects in the hippocampus.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blotting, Western | 2013 |
Hyperphosphorylation of Tau at Ser396 occurs in the much earlier stage than appearance of learning and memory disorders in 5XFAD mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Gene Expression | 2014 |
Designer receptors enhance memory in a mouse model of Down syndrome.
Topics: Animals; Antipsychotic Agents; Cell Count; Clozapine; Cross-Over Studies; Designer Drugs; Disease Mo | 2015 |
Two Binges of Ethanol a Day Keep the Memory Away in Adolescent Rats: Key Role for GLUN2B Subunit.
Topics: Animals; Animals, Newborn; Binge Drinking; Central Nervous System Depressants; Electric Stimulation; | 2015 |
Escitalopram Ameliorates Tau Hyperphosphorylation and Spatial Memory Deficits Induced by Protein Kinase A Activation in Sprague Dawley Rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Citalopram; Colforsin; Disease Models, Animal; En | 2015 |
Modulation of glycine sites enhances social memory in rats using PQQ combined with d-serine.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Drug Contamination; Drug Synergism; G | 2016 |
NR2A-Containing NMDARs in the Prefrontal Cortex Are Required for Working Memory and Associated with Age-Related Cognitive Decline.
Topics: Aging; Animals; Cognitive Dysfunction; Conditioning, Operant; Excitatory Amino Acid Antagonists; Mal | 2016 |
Hippocampal levels of phosphorylated protein kinase A (phosphor-S96) are linked to spatial memory enhancement by SGS742.
Topics: Amino Acid Sequence; Animals; Cyclic AMP-Dependent Protein Kinases; GABA Antagonists; GABA-B Recepto | 2009 |
Association of the SerCys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding.
Topics: Adult; Alleles; Amino Acid Sequence; Amino Acid Substitution; Cysteine; DNA Mutational Analysis; Fem | 2008 |
Serine racemase deletion disrupts memory for order and alters cortical dendritic morphology.
Topics: Animals; Brain; Cerebral Cortex; Coloring Agents; Conditioning, Operant; Dendrites; Memory Disorders | 2011 |
α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies.
Topics: Acoustic Stimulation; Age Factors; alpha-Synuclein; Analysis of Variance; Animals; Animals, Newborn; | 2011 |
Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory.
Topics: Androstadienes; Animals; Antibodies, Monoclonal; Behavior, Animal; Blotting, Western; Dose-Response | 2003 |
Spatial memory deficits induced by perinatal treatment of rats with PCP and reversal effect of D-serine.
Topics: Animals; Animals, Newborn; Behavior, Animal; Conditioning, Classical; Dose-Response Relationship, Dr | 2004 |
Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans.
Topics: Amino Acid Sequence; Animals; Anxiety; Behavior, Animal; Cell Movement; Cerebral Cortex; Chromosome | 2007 |