serine has been researched along with Adipocere in 14 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Excerpt | Relevance | Reference |
---|---|---|
"Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disease characterized by behavioral abnormalities, personality changes, language dysfunction, and can co-occur with the development of motor neuron disease." | 1.36 | Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. ( Duong, DM; Gearing, M; Herskowitz, JH; Lah, JJ; Levey, AI; Peng, J; Rees, HD; Seyfried, NT; Xia, Q, 2010) |
"Glycine was distributed fairly uniformly with large concentrations in certain lower brainstem nuclei." | 1.27 | Concentrations of GABA and glycine in discrete brain nuclei. Stress-induced changes in the levels of inhibitory amino acids. ( Elekes, I; Láng, T; Palkovits, M; Patthy, A, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (14.29) | 18.7374 |
1990's | 2 (14.29) | 18.2507 |
2000's | 5 (35.71) | 29.6817 |
2010's | 5 (35.71) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Keller, S | 1 |
Punzo, D | 1 |
Cuomo, M | 1 |
Affinito, O | 1 |
Coretti, L | 1 |
Sacchi, S | 1 |
Florio, E | 1 |
Lembo, F | 1 |
Carella, M | 1 |
Copetti, M | 1 |
Cocozza, S | 1 |
Balu, DT | 1 |
Errico, F | 1 |
Usiello, A | 1 |
Chiariotti, L | 1 |
Mamais, A | 1 |
Raja, M | 1 |
Manzoni, C | 1 |
Dihanich, S | 1 |
Lees, A | 1 |
Moore, D | 1 |
Lewis, PA | 1 |
Bandopadhyay, R | 1 |
Jin, N | 1 |
Wu, Y | 1 |
Xu, W | 1 |
Gong, CX | 2 |
Iqbal, K | 2 |
Liu, F | 2 |
Ma, QL | 1 |
Yang, F | 1 |
Rosario, ER | 1 |
Ubeda, OJ | 1 |
Beech, W | 1 |
Gant, DJ | 1 |
Chen, PP | 1 |
Hudspeth, B | 1 |
Chen, C | 1 |
Zhao, Y | 1 |
Vinters, HV | 1 |
Frautschy, SA | 1 |
Cole, GM | 1 |
Herskowitz, JH | 1 |
Seyfried, NT | 1 |
Duong, DM | 1 |
Xia, Q | 1 |
Rees, HD | 1 |
Gearing, M | 1 |
Peng, J | 1 |
Lah, JJ | 1 |
Levey, AI | 1 |
Muntané, G | 1 |
Ferrer, I | 1 |
Martinez-Vicente, M | 1 |
Webber, KM | 1 |
Smith, MA | 1 |
Lee, HG | 1 |
Harris, PL | 1 |
Moreira, P | 1 |
Perry, G | 1 |
Zhu, X | 1 |
Li, X | 1 |
Friedman, AB | 1 |
Roh, MS | 1 |
Jope, RS | 1 |
Griffin, RJ | 1 |
Moloney, A | 1 |
Kelliher, M | 1 |
Johnston, JA | 1 |
Ravid, R | 1 |
Dockery, P | 1 |
O'Connor, R | 1 |
O'Neill, C | 1 |
Grundke-Iqbal, I | 1 |
Kumashiro, S | 2 |
Hashimoto, A | 1 |
Nishikawa, T | 1 |
Kurumaji, A | 1 |
Watanabe, A | 1 |
Semba, J | 1 |
Toru, M | 1 |
Elekes, I | 1 |
Patthy, A | 1 |
Láng, T | 1 |
Palkovits, M | 1 |
Shank, RP | 1 |
Aprison, MH | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Curcumin and Yoga Exercise Effects in Veterans at Risk for Alzheimer's Disease[NCT01811381] | Phase 2 | 80 participants (Anticipated) | Interventional | 2014-01-20 | Active, not recruiting | ||
A Trial of the Effects of Glycine Loading on Clinical Symptoms and Logical Memory in Patients With Schizophrenia[NCT00575848] | Phase 1 | 16 participants (Anticipated) | Interventional | 2007-12-31 | Terminated (stopped due to Slow enrollment and due to personnel change there was no viable way to quantify glycine levels through imaging) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
14 other studies available for serine and Adipocere
Article | Year |
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DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia.
Topics: Alleles; Brain; Case-Control Studies; D-Amino-Acid Oxidase; D-Aspartate Oxidase; D-Aspartic Acid; DN | 2018 |
Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases.
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Brain; Female; Gene Expression Regulation; Glycine; Humans | 2013 |
C-terminal truncation of GSK-3β enhances its dephosphorylation by PP2A.
Topics: Active Transport, Cell Nucleus; Aged, 80 and over; Alzheimer Disease; Animals; Autopsy; Blotting, We | 2017 |
Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; A | 2009 |
Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration.
Topics: Aged; Amino Acid Sequence; Binding Sites; Brain; Chromatography, Affinity; Chromatography, Liquid; D | 2010 |
α-synuclein phosphorylation and truncation are normal events in the adult human brain.
Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Animals; Brain; Cell Line, Tumor; Female; Humans; L | 2012 |
Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Hippocampus; Histones; Hum | 2005 |
Anesthesia and post-mortem interval profoundly influence the regulatory serine phosphorylation of glycogen synthase kinase-3 in mouse brain.
Topics: Anesthesia; Anesthetics; Animals; Brain; Chloral Hydrate; Glycogen Synthase Kinase 3; Halothane; Iso | 2005 |
Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antibodies, Monoclonal; Blotting, Western; Cerebral Cort | 2005 |
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation.
Topics: Aged, 80 and over; Alzheimer Disease; Catalytic Domain; Dose-Response Relationship, Drug; Enzyme Act | 2005 |
Free D-serine in post-mortem brains and spinal cords of individuals with and without neuropsychiatric diseases.
Topics: Aging; Amino Acids; Animals; Brain Chemistry; Humans; Mental Disorders; Nervous System Diseases; Par | 1995 |
A postmortem study of glycine and its potential precursors in chronic schizophrenics.
Topics: Adult; Aged; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Female; Glycine | 1996 |
Concentrations of GABA and glycine in discrete brain nuclei. Stress-induced changes in the levels of inhibitory amino acids.
Topics: Animals; Brain Chemistry; gamma-Aminobutyric Acid; Glycine; Male; Postmortem Changes; Rats; Rats, In | 1986 |
Post mortem changes in the content and specific radioactivity of several amino acids in four areas of the rat brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Isotopes; Cerebellum; Ce | 1971 |