Page last updated: 2024-11-08

serine and Adenoma Sebaceum

serine has been researched along with Adenoma Sebaceum in 10 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Adenoma Sebaceum: Facial ANGIOFIBROMA in tuberous sclerosis

Research Excerpts

ExcerptRelevanceReference
"Interestingly, in certain types of cancers (e."1.34Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer. ( Bernardi, R; Bonner, P; Cordon-Cardo, C; Franz, DN; Ma, L; Pandolfi, PP; Teruya-Feldstein, J; Witte, D, 2007)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (70.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Dutta, R1
Sharma, MC1
Suri, V1
Sarkar, C1
Garg, A1
Suri, A1
Kale, SS1
Krishnamoorthy, J1
Tenkerian, C1
Gupta, J1
Ghaddar, N1
Wang, S1
Darini, C1
Staschke, KA1
Ghosh, A1
Gandin, V1
Topisirovic, I1
Kristof, AS1
Hatzoglou, M1
Simos, G1
Koromilas, AE1
Madigan, JP1
Hou, F1
Ye, L1
Hu, J1
Dong, A1
Tempel, W1
Yohe, ME1
Randazzo, PA1
Jenkins, LMM1
Gottesman, MM1
Tong, Y1
Di Nardo, A1
Kramvis, I1
Cho, N1
Sadowski, A1
Meikle, L1
Kwiatkowski, DJ1
Sahin, M1
Li, Y2
Inoki, K2
Yeung, R1
Guan, KL2
Vacratsis, P1
Roux, PP1
Ballif, BA1
Anjum, R1
Gygi, SP1
Blenis, J1
Ma, L2
Chen, Z1
Erdjument-Bromage, H1
Tempst, P1
Pandolfi, PP2
Teruya-Feldstein, J1
Bonner, P1
Bernardi, R1
Franz, DN1
Witte, D1
Cordon-Cardo, C1
Pipo, JR1
Yamamoto, T1
Takeda, H1
Maegawa, S1
Nanba, E1
Ninomiya, H1
Ohno, K1
Takeshita, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of Nintedanib for LymphAngioleioMyomatosis (LAM)[NCT03062943]Phase 230 participants (Actual)Interventional2016-12-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

10 other studies available for serine and Adenoma Sebaceum

ArticleYear
TTF-1: A Well-Favored Addition to the Immunohistochemistry Armamentarium as a Diagnostic Marker of SEGA.
    World neurosurgery, 2022, Volume: 159

    Topics: Astrocytoma; Brain Neoplasms; Child; Ependymoma; Glioblastoma; Humans; Immunohistochemistry; Neurocy

2022
Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.
    Cell death & disease, 2018, 02-15, Volume: 9, Issue:3

    Topics: Animals; Antioxidants; Cell Death; Cells, Cultured; Down-Regulation; eIF-2 Kinase; Eukaryotic Initia

2018
The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation-mediated 14-3-3 binding.
    The Journal of biological chemistry, 2018, 10-19, Volume: 293, Issue:42

    Topics: 14-3-3 Proteins; beta-Transducin Repeat-Containing Proteins; Binding Sites; Carrier Proteins; Crysta

2018
Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, May-06, Volume: 29, Issue:18

    Topics: Animals; Animals, Newborn; Apoptosis; Carrier Proteins; Cells, Cultured; Child, Preschool; Dose-Resp

2009
Regulation of TSC2 by 14-3-3 binding.
    The Journal of biological chemistry, 2002, Nov-22, Volume: 277, Issue:47

    Topics: 14-3-3 Proteins; Adaptor Proteins, Signal Transducing; Animals; Binding Sites; Carrier Proteins; Cel

2002
The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.
    The Journal of biological chemistry, 2003, Apr-18, Volume: 278, Issue:16

    Topics: 14-3-3 Proteins; Amino Acid Sequence; Androstadienes; Anisomycin; Binding Sites; Culture Media, Seru

2003
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Sep-14, Volume: 101, Issue:37

    Topics: Amino Acid Sequence; Animals; Cell Line; Enzyme Activation; Humans; MAP Kinase Signaling System; Mod

2004
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.
    Cell, 2005, Apr-22, Volume: 121, Issue:2

    Topics: Amino Acid Sequence; Animals; Cell Line; Extracellular Signal-Regulated MAP Kinases; Humans; In Vitr

2005
Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer.
    Cancer research, 2007, Aug-01, Volume: 67, Issue:15

    Topics: Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Humans; Immunoblotting; Immunoprecipita

2007
Two novel serine repeat length polymorphisms (1043insS and 1043insSS) at exon 23 of the TSC1 gene.
    Human mutation, 2000, Volume: 16, Issue:4

    Topics: Exons; Genes, Tumor Suppressor; Humans; Mutagenesis, Insertional; Polymorphism, Genetic; Proteins; R

2000