serine has been researched along with Acute Promyelocytic Leukemia in 8 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arsenic trioxide (As(2)O(3)) is highly effective for the treatment of acute promyelocytic leukemia, even in patients who are unresponsive to all-trans-retinoic acid therapy." | 7.71 | Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells. ( Barnes, J; Chen, P; Chrest, FJ; Gorospe, M; Li, J; Liu, Y; Sinogeeva, N; Wersto, RP, 2002) |
| "Arsenic trioxide (As(2)O(3)) is highly effective for the treatment of acute promyelocytic leukemia, even in patients who are unresponsive to all-trans-retinoic acid therapy." | 3.71 | Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells. ( Barnes, J; Chen, P; Chrest, FJ; Gorospe, M; Li, J; Liu, Y; Sinogeeva, N; Wersto, RP, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nasr, R | 1 |
| Guillemin, MC | 1 |
| Ferhi, O | 1 |
| Soilihi, H | 1 |
| Peres, L | 1 |
| Berthier, C | 1 |
| Rousselot, P | 1 |
| Robledo-Sarmiento, M | 1 |
| Lallemand-Breitenbach, V | 1 |
| Gourmel, B | 1 |
| Vitoux, D | 1 |
| Pandolfi, PP | 1 |
| Rochette-Egly, C | 1 |
| Zhu, J | 1 |
| de Thé, H | 1 |
| Seshire, A | 1 |
| Rößiger, T | 1 |
| Frech, M | 1 |
| Beez, S | 1 |
| Hagemeyer, H | 1 |
| Puccetti, E | 1 |
| Li, J | 1 |
| Chen, P | 1 |
| Sinogeeva, N | 1 |
| Gorospe, M | 1 |
| Wersto, RP | 1 |
| Chrest, FJ | 1 |
| Barnes, J | 1 |
| Liu, Y | 1 |
| Lal, L | 1 |
| Li, Y | 1 |
| Smith, J | 1 |
| Sassano, A | 1 |
| Uddin, S | 1 |
| Parmar, S | 1 |
| Tallman, MS | 1 |
| Minucci, S | 1 |
| Hay, N | 1 |
| Platanias, LC | 1 |
| Mann, KK | 1 |
| Padovani, AM | 1 |
| Guo, Q | 1 |
| Colosimo, AL | 1 |
| Lee, HY | 1 |
| Kurie, JM | 1 |
| Miller, WH | 1 |
| Luo, LY | 1 |
| Huang, J | 1 |
| Gou, BD | 1 |
| Zhang, TL | 1 |
| Wang, K | 1 |
| Zada, AA | 1 |
| Geletu, MH | 1 |
| Pulikkan, JA | 1 |
| Müller-Tidow, C | 1 |
| Reddy, VA | 1 |
| Christopeit, M | 1 |
| Hiddemann, WD | 1 |
| Behre, HM | 1 |
| Tenen, DG | 1 |
| Behre, G | 1 |
| Lohmander, LS | 1 |
| Arnljots, K | 1 |
| Yanagishita, M | 1 |
8 other studies available for serine and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic | 2008 |
Direct interaction of PU.1 with oncogenic transcription factors reduces its serine phosphorylation and promoter binding.
Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Chromatin Immunoprecipitation; Fl | 2012 |
Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells.
Topics: Acetylation; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Northern; Blo | 2002 |
Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells.
Topics: Cell Differentiation; Cell Line, Tumor; Enzyme Activation; Eukaryotic Initiation Factor-4E; Growth I | 2005 |
Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Carcinogens, Environmental; | 2005 |
Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by arsenic sulphide: involvement of serine/threonine protein phosphatases.
Topics: Arsenicals; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; HL-60 Cells; | 2006 |
Proteomic analysis of acute promyelocytic leukemia: PML-RARalpha leads to decreased phosphorylation of OP18 at serine 63.
Topics: Cell Line; Clone Cells; Computational Biology; Electrophoresis, Gel, Two-Dimensional; Gene Expressio | 2006 |
Structure and synthesis of intracellular proteoglycan in HL-60 human leukemic promyelocytes.
Topics: Amino Acids; Chondroitin Lyases; Chondroitin Sulfates; Chromatography, Gel; Culture Media; Electroph | 1990 |