serine has been researched along with Acute Post-Traumatic Stress Disorder in 4 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Post-traumatic stress disorder (PTSD) is a chronic and debilitating condition that is often refractory to standard frontline antidepressant therapy." | 2.87 | d-Serine is a potential biomarker for clinical response in treatment of post-traumatic stress disorder using (R,S)-ketamine infusion and TIMBER psychotherapy: A pilot study. ( Mitrev, L; Moaddell, R; Pradhan, B; Wainer, IW, 2018) |
| "Twenty-two chronic PTSD outpatients were randomly assigned to participate in a 6-wk double-blind, placebo-controlled, crossover trial with 30 mg/kg x d DSR used as monotherapy or add-on pharmacotherapy." | 2.74 | Pilot controlled trial of D-serine for the treatment of post-traumatic stress disorder. ( Balan, L; Bloch, B; Deutsch, L; Dumin, E; Heresco-Levy, U; Kremer, I; Vass, A; Wolosker, H, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balu, DT | 1 |
| Presti, KT | 1 |
| Huang, CCY | 1 |
| Muszynski, K | 1 |
| Radzishevsky, I | 1 |
| Wolosker, H | 2 |
| Guffanti, G | 1 |
| Ressler, KJ | 1 |
| Coyle, JT | 1 |
| Pradhan, B | 1 |
| Mitrev, L | 1 |
| Moaddell, R | 1 |
| Wainer, IW | 1 |
| Szabo, ST | 1 |
| Kilts, JD | 1 |
| Naylor, JC | 1 |
| Youssef, NA | 1 |
| Strauss, JL | 1 |
| Morey, RA | 1 |
| Brancu, M | 1 |
| Hamer, RM | 1 |
| Bradford, DW | 1 |
| Marx, CE | 1 |
| Heresco-Levy, U | 1 |
| Vass, A | 1 |
| Bloch, B | 1 |
| Dumin, E | 1 |
| Balan, L | 1 |
| Deutsch, L | 1 |
| Kremer, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessing a Combined Ketamine and Online Cognitive Behavioural Therapy Intervention for Treatment Resistant Post-Traumatic Stress Disorder[NCT04771767] | Phase 2 | 16 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | ||
| D-serine for Posttraumatic Stress Disorder Treatment[NCT00215878] | Phase 2 | 22 participants (Actual) | Interventional | 2003-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for serine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
d-Serine is a potential biomarker for clinical response in treatment of post-traumatic stress disorder using (R,S)-ketamine infusion and TIMBER psychotherapy: A pilot study.
Topics: Adult; Biomarkers; Double-Blind Method; Female; Humans; Ketamine; Male; Middle Aged; Mindfulness; Pi | 2018 |
Pilot controlled trial of D-serine for the treatment of post-traumatic stress disorder.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Excitatory Amino Acid Ago | 2009 |
2 other studies available for serine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning.
Topics: Adult; Amygdala; Animals; Conditioning, Classical; Extinction, Psychological; Fear; Genome-Wide Asso | 2018 |
Amino acids as biomarker candidates for suicidality in male OEF/OIF Veterans: relevance to NMDA receptor modulation and nitric oxide signaling.
Topics: Afghan Campaign 2001-; Amino Acids; Arginine; Citrulline; Humans; Iraq War, 2003-2011; Male; Pilot P | 2014 |