serine has been researched along with Acute Kidney Failure in 23 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of D-serine to rats induced acute necrosis of the proximal straight tubules, proteinuria, glucosuria, and aminoaciduria." | 7.65 | D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis. ( Carone, FA; Ganote, CE, 1975) |
| "d-Serine, a long-term undetected enantiomer of serine, is now showing its potential as a biomarker for kidney diseases." | 5.05 | Utility of d-serine monitoring in kidney disease. ( Hesaka, A; Isaka, Y; Kimura, T, 2020) |
| "Chronic nicotine (Ch-NIC) exposure exacerbates ischemia/reperfusion (I/R)-induced oxidative stress and acute kidney injury (AKI), and mitochondrial production of reactive oxygen species (ROS) in cultured renal proximal tubule cells (RPTCs)." | 3.79 | Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc. ( Arany, I; Clark, J; Juncos, LA; Reed, DK, 2013) |
| "Administration of D-serine to rats induced acute necrosis of the proximal straight tubules, proteinuria, glucosuria, and aminoaciduria." | 3.65 | D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis. ( Carone, FA; Ganote, CE, 1975) |
| "In maleic acid-treated rats the site and extent of tubular necrosis and the nature of urinary loss of solutes were studied." | 1.27 | Urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid. ( Carone, FA; Goldman, B; Nakamura, S, 1985) |
| "In similarly treated rats, proteinuria and glucosuria developed at the onset of tubular necrosis and disappeared when the tubules were completely relined by epithelium suggesting that they are due to diffusion of protein and glucose from interstitium into tubular fluid across the denuded basement membranes and that epithelial cells, under normal conditions, act as a barrier to diffusion of certain substances between the interstitium and tubular fluid." | 1.25 | The nature of D-serine--induced nephrotoxicity. ( Carone, FA; Ganote, CE; Peterson, DR, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (43.48) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, L | 1 |
| Fan, D | 1 |
| Zhou, L | 1 |
| Wei, S | 1 |
| Kimura, T | 2 |
| Hesaka, A | 2 |
| Isaka, Y | 2 |
| Spasova, K | 1 |
| Fähling, M | 1 |
| Navarrete, M | 1 |
| Ho, J | 1 |
| Dwivedi, RC | 1 |
| Choi, N | 1 |
| Ezzati, P | 1 |
| Spicer, V | 1 |
| Arora, RC | 1 |
| Rigatto, C | 1 |
| Wilkins, JA | 1 |
| Nakade, Y | 1 |
| Iwata, Y | 1 |
| Furuichi, K | 1 |
| Mita, M | 3 |
| Hamase, K | 3 |
| Konno, R | 2 |
| Miyake, T | 1 |
| Sakai, N | 1 |
| Kitajima, S | 1 |
| Toyama, T | 1 |
| Shinozaki, Y | 1 |
| Sagara, A | 1 |
| Miyagawa, T | 1 |
| Hara, A | 1 |
| Shimizu, M | 1 |
| Kamikawa, Y | 1 |
| Sato, K | 1 |
| Oshima, M | 1 |
| Yoneda-Nakagawa, S | 1 |
| Yamamura, Y | 1 |
| Kaneko, S | 1 |
| Miyamoto, T | 1 |
| Katane, M | 1 |
| Homma, H | 1 |
| Morita, H | 1 |
| Suda, W | 1 |
| Hattori, M | 1 |
| Wada, T | 1 |
| Yasuda, K | 1 |
| Sakai, S | 1 |
| Yonishi, H | 1 |
| Namba-Hamano, T | 1 |
| Takahashi, A | 1 |
| Mizui, M | 1 |
| Matsui, R | 1 |
| Horio, M | 1 |
| Sasabe, J | 1 |
| Suzuki, M | 1 |
| Miyoshi, Y | 1 |
| Tojo, Y | 1 |
| Okamura, C | 1 |
| Ito, S | 1 |
| Aiso, S | 1 |
| Schmidt, JJ | 1 |
| Hafer, C | 1 |
| Spielmann, J | 1 |
| Hadem, J | 1 |
| Schönenberger, E | 1 |
| Schmidt, BM | 1 |
| Kielstein, JT | 1 |
| Lin, CS | 1 |
| Hung, SF | 1 |
| Huang, HS | 1 |
| Ma, MC | 1 |
| Arany, I | 2 |
| Faisal, A | 1 |
| Clark, JS | 1 |
| Vera, T | 1 |
| Baliga, R | 1 |
| Nagamine, Y | 1 |
| Hodeify, R | 1 |
| Tarcsafalvi, A | 1 |
| Megyesi, J | 1 |
| Safirstein, RL | 1 |
| Price, PM | 1 |
| Clark, J | 1 |
| Reed, DK | 1 |
| Juncos, LA | 1 |
| Markaryan, AA | 1 |
| Alyautdin, RN | 1 |
| Mondodoev, AG | 1 |
| Stepinski, J | 1 |
| Hörl, WH | 1 |
| Heidland, A | 1 |
| Kaltenbach, JP | 2 |
| Carone, FA | 6 |
| Ganote, CE | 4 |
| Peterson, DR | 2 |
| Nakamura, S | 1 |
| Goldman, B | 1 |
| Kennedy, A | 1 |
| Saluga, PG | 1 |
| Cuppage, FE | 1 |
| Tate, A | 1 |
| Tapp, E | 1 |
| Lowe, MB | 1 |
1 review available for serine and Acute Kidney Failure
| Article | Year |
|---|---|
Utility of d-serine monitoring in kidney disease.
Topics: Acute Kidney Injury; Biomarkers; Clinical Decision-Making; Glomerular Filtration Rate; Humans; Kidne | 2020 |
1 trial available for serine and Acute Kidney Failure
| Article | Year |
|---|---|
Removal characteristics and total dialysate content of glutamine and other amino acids in critically ill patients with acute kidney injury undergoing extended dialysis.
Topics: Acute Kidney Injury; Amino Acids; Critical Illness; Cross-Over Studies; Dialysis Solutions; Glutamin | 2014 |
21 other studies available for serine and Acute Kidney Failure
| Article | Year |
|---|---|
The influence of modified molecular (D/L-serine) chirality on the theragnostics of PAMAM-based nanomedicine for acute kidney injury.
Topics: Acute Kidney Injury; Animals; Dendrimers; Fluorescent Dyes; Hydrogen Peroxide; Mice; Molecular Struc | 2021 |
D-serine-A useful biomarker for renal injury?
Topics: Acute Kidney Injury; Biomarkers; Humans; Kidney; Serine | 2020 |
Activity-Based Protein Profiling of Intraoperative Serine Hydrolase Activities during Cardiac Surgery.
Topics: Acute Kidney Injury; Aged; Cardiopulmonary Bypass; Case-Control Studies; Female; Humans; Hydrolases; | 2018 |
Gut microbiota-derived D-serine protects against acute kidney injury.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Biomarkers; Disease Models, Animal; Dysbiosis; F | 2018 |
Dynamics of D-serine reflected the recovery course of a patient with rapidly progressive glomerulonephritis.
Topics: Acute Kidney Injury; Adult; Antibodies, Antineutrophil Cytoplasmic; Creatinine; Cyclophosphamide; Di | 2019 |
Ischemic acute kidney injury perturbs homeostasis of serine enantiomers in the body fluid in mice: early detection of renal dysfunction using the ratio of serine enantiomers.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Creatinine; Cystatin C; D-Amino-Acid Oxidase; Hu | 2014 |
Blockade of the N-Methyl-D-Aspartate Glutamate Receptor Ameliorates Lipopolysaccharide-Induced Renal Insufficiency.
Topics: Acute Kidney Injury; Animals; Cells, Cultured; Dizocilpine Maleate; Dogs; Endotoxemia; Excitatory Am | 2015 |
p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury.
Topics: Acute Kidney Injury; Animals; Cell Line; Cytochromes c; Hydrogen Peroxide; Kidney Tubules, Proximal; | 2010 |
Cdk2-dependent phosphorylation of p21 regulates the role of Cdk2 in cisplatin cytotoxicity.
Topics: Acute Kidney Injury; Adenoviridae; Amino Acid Sequence; Animals; Antineoplastic Agents; Cisplatin; C | 2011 |
Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Cells, Cultured; Cytochromes c; Hydrogen Peroxide; | 2013 |
Amino acid composition of Nephrophyt, a new complex plant preparation and its possible role in correction of mercuric chloride-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Amino Acids; Animals; Female; Male; Mercuric Chloride; Phytotherapy; Plant Prep | 2004 |
The gluconeogenetic ability of hepatocytes in various types of acute uraemia.
Topics: Acute Disease; Acute Kidney Injury; Animals; Dihydroxyacetone; Female; Fructose; Gluconeogenesis; Gl | 1982 |
Compounds protective against renal tubular necrosis induced by D-serine and D-2,3-diaminopropionic acid in the rat.
Topics: Acute Kidney Injury; Alanine; Amino Acids; Animals; beta-Alanine; Kidney Tubular Necrosis, Acute; Ra | 1982 |
Renal tubular necrosis induced by compounds structurally related to D-serine.
Topics: Acute Kidney Injury; Animals; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Necros | 1979 |
Renal regeneration following d-serine induced acute tubular necrosis.
Topics: Acute Kidney Injury; Animals; Basement Membrane; Cell Differentiation; Cell Membrane; Cytoplasm; Kid | 1979 |
D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis.
Topics: Acute Kidney Injury; Animals; Glycosuria; Kidney Tubular Necrosis, Acute; Kidney Tubules; Male; Pota | 1975 |
Urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid.
Topics: Acute Kidney Injury; Animals; Carbon Radioisotopes; Glomerular Filtration Rate; Glucose; Glycosuria; | 1985 |
The nature of D-serine--induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Cytoplasm; Diffusion; Epithelial Cells; Epithelium; Glycosuria; Kidney | 1974 |
Urinary cytology in experimental toxic renal injury.
Topics: Acute Kidney Injury; Animals; Aspirin; Azirines; Chromates; Eosinophils; Histocytochemistry; Kidney | 1970 |
Repair of the nephron in acute renal failure: comparative regeneration following various forms of acute tubular injury.
Topics: Acute Kidney Injury; Animals; Chromates; Creatinine; Ischemia; Kidney Function Tests; Kidney Tubules | 1968 |
Tetracycline toxicity.
Topics: Acute Kidney Injury; Animals; Chromates; Female; Glomerular Filtration Rate; Ischemia; Nitrates; Rat | 1966 |