serine has been researched along with Acute Brain Injuries in 15 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " During long-term administration of thiopental and midazolam, pathologically elevated ventricular CSF glutamate levels were associated with significantly increased glutamine and alanine levels up to 14 days after trauma." | 2.69 | Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients. ( Kempski, OS; Kossmann, T; Morganti-Kossmann, MC; Pleines, UE; Stocker, R; Stover, JF, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Tapanes, SA | 2 |
| Arizanovska, D | 1 |
| Díaz, MM | 1 |
| Folorunso, OO | 1 |
| Harvey, T | 1 |
| Brown, SE | 1 |
| Radzishevsky, I | 1 |
| Close, LN | 1 |
| Jagid, JR | 1 |
| Graciolli Cordeiro, J | 1 |
| Wolosker, H | 1 |
| Balu, DT | 2 |
| Liebl, DJ | 2 |
| He, Z | 1 |
| Tao, D | 1 |
| Xiong, J | 1 |
| Lou, F | 1 |
| Zhang, J | 1 |
| Chen, J | 1 |
| Dai, W | 1 |
| Sun, J | 1 |
| Wang, Y | 1 |
| Perez, EJ | 1 |
| Loris, ZB | 1 |
| Sick, TJ | 1 |
| Coyle, JT | 1 |
| Cohen-Yeshurun, A | 2 |
| Willner, D | 1 |
| Trembovler, V | 3 |
| Alexandrovich, A | 3 |
| Mechoulam, R | 3 |
| Shohami, E | 3 |
| Leker, RR | 2 |
| Mann, A | 1 |
| Smoum, R | 1 |
| Breuer, A | 1 |
| Zhai, PP | 1 |
| Xu, LH | 1 |
| Yang, JJ | 1 |
| Jiang, ZL | 1 |
| Zhao, GW | 1 |
| Sun, L | 1 |
| Wang, GH | 1 |
| Li, X | 1 |
| Xu, L | 1 |
| Ryu, J | 1 |
| Nguyen, JV | 1 |
| Arena, J | 1 |
| Rha, E | 1 |
| Vranis, P | 1 |
| Hitt, D | 1 |
| Marsh-Armstrong, N | 1 |
| Koliatsos, VE | 1 |
| Lee, HT | 1 |
| Chang, YC | 1 |
| Tu, YF | 1 |
| Huang, CC | 1 |
| Ryberg, E | 1 |
| Greasley, PJ | 1 |
| Brecht, S | 1 |
| Kirchhof, R | 1 |
| Chromik, A | 1 |
| Willesen, M | 1 |
| Nicolaus, T | 1 |
| Raivich, G | 1 |
| Wessig, J | 1 |
| Waetzig, V | 1 |
| Goetz, M | 1 |
| Claussen, M | 1 |
| Pearse, D | 1 |
| Kuan, CY | 1 |
| Vaudano, E | 1 |
| Behrens, A | 1 |
| Wagner, E | 1 |
| Flavell, RA | 1 |
| Davis, RJ | 1 |
| Herdegen, T | 1 |
| Neary, JT | 1 |
| Kang, Y | 1 |
| Tran, M | 1 |
| Feld, J | 1 |
| Palmer, AM | 1 |
| Marion, DW | 1 |
| Botscheller, ML | 1 |
| Swedlow, PE | 1 |
| Styren, SD | 1 |
| DeKosky, ST | 1 |
| Kuchiwaki, H | 1 |
| Inao, S | 1 |
| Yamamoto, M | 1 |
| Yoshida, K | 1 |
| Sugita, K | 1 |
| Stover, JF | 1 |
| Pleines, UE | 1 |
| Morganti-Kossmann, MC | 1 |
| Stocker, R | 1 |
| Kempski, OS | 1 |
| Kossmann, T | 1 |
| Gründig, E | 1 |
| Gerstenbrand, F | 1 |
1 review available for serine and Acute Brain Injuries
| Article | Year |
|---|---|
Phosphorylation of 5-LOX: The Potential Set-point of Inflammation.
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain; Brain Injuries; Humans; Inflammation; Lipoxygenase Inhi | 2020 |
1 trial available for serine and Acute Brain Injuries
| Article | Year |
|---|---|
Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients.
Topics: Adolescent; Adult; Aged; Alanine; Brain Injuries; Cerebral Ventricles; Glutamic Acid; Glutamine; Hum | 1999 |
13 other studies available for serine and Acute Brain Injuries
| Article | Year |
|---|---|
Inhibition of glial D-serine release rescues synaptic damage after brain injury.
Topics: Amino Acid Transport System ASC; Animals; Astrocytes; Brain Injuries; Humans; Mice; Neuroglia; Neuro | 2022 |
Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury.
Topics: Animals; Astrocytes; Brain; Brain Injuries; Brain Injuries, Traumatic; Cells, Cultured; Gliosis; Glu | 2017 |
N-arachidonoyl-L-serine (AraS) possesses proneurogenic properties in vitro and in vivo after traumatic brain injury.
Topics: Animals; Arachidonic Acids; Astrocytes; Behavior, Animal; Blotting, Western; Brain; Brain Injuries; | 2013 |
Palmitoyl Serine: An Endogenous Neuroprotective Endocannabinoid-Like Entity After Traumatic Brain Injury.
Topics: Animals; Arachidonic Acids; Brain Injuries; Dose-Response Relationship, Drug; Endocannabinoids; Glyc | 2015 |
Reduction of inflammatory responses by L-serine treatment leads to neuroprotection in mice after traumatic brain injury.
Topics: Animals; Apoptosis; Astrocytes; Brain; Brain Edema; Brain Injuries; Cytokines; Disease Models, Anima | 2015 |
Evidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury.
Topics: Analysis of Variance; Animals; Brain Injuries; Cell Count; Cerebral Cortex; Disease Models, Animal; | 2015 |
CREB activation mediates VEGF-A's protection of neurons and cerebral vascular endothelial cells.
Topics: Animals; Animals, Newborn; Brain Injuries; Cell Survival; Cells, Cultured; Chromones; CREB-Binding P | 2010 |
N-arachidonoyl-L-serine is neuroprotective after traumatic brain injury by reducing apoptosis.
Topics: Animals; Apoptosis; Arachidonic Acids; Brain Injuries; Male; Mice; Mitogen-Activated Protein Kinase | 2011 |
Specific pathophysiological functions of JNK isoforms in the brain.
Topics: Animals; Autonomic Denervation; Behavior, Animal; Blotting, Western; Brain; Brain Injuries; Cell Cou | 2005 |
Traumatic injury activates protein kinase B/Akt in cultured astrocytes: role of extracellular ATP and P2 purinergic receptors.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Brain Injuries; Calcium Channels; Cel | 2005 |
Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Brain | 1993 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats | 1994 |
[Correlation between Parkinsonism symptoms and a disorder in the amino acid metabolism in CNS].
Topics: Amino Acids; Animals; Brain Injuries; Central Nervous System Diseases; Cerebrospinal Fluid; Cysteine | 1970 |