seneciphylline and Plant-Poisoning

seneciphylline has been researched along with Plant-Poisoning* in 1 studies

Other Studies

1 other study(ies) available for seneciphylline and Plant-Poisoning

ArticleYear
Interplant alkaloid variation and Senecio vernalis toxicity in cattle.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:3

    Senecio vernalis and other plants containing pyrrolizidine alkaloids (PA) are implicated in the poisoning of cattle. The liver is a known target organ. In this study the content of the alkaloids senecionine (SCO), senkirkin (SKK) and seneciphyllin (SCP) and their toxic effects in cattle were studied. The content of these 3 compounds only varied by a factor of 2 within 10 plant collections at different locations in western Denmark (Jutland). However, individual alkaloids varied 3-fold, and the interplant variation for some of the PA up to 8-fold. SCO and SKK had very short half lives, 20 min and 70 min respectively. In cattle fed dried plant material corresponding to 200 and 400 g of fresh material for 10 d alanine aminotransferase, alkaline phosphatase and g-glutamyl transferase activities remained unchanged. Cattle subsequently fed fresh plant material up to 1 kg/d for 8 d also had no change in liver enzyme activities. Cattle did not show any clinical signs of poisoning, and no morphological liver changes were observed.

    Topics: Animal Feed; Animals; Cattle; Cattle Diseases; Chromatography, High Pressure Liquid; Denmark; Female; gamma-Glutamyltransferase; Liver; Plant Poisoning; Plants, Toxic; Pyrrolizidine Alkaloids; Senecio

2001