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semustine and Vomiting

semustine has been researched along with Vomiting in 11 studies

Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"One hundred and fifty-seven evaluable patients with advanced metastatic malignant melanoma were randomly assigned to receive either methyl-CCNU (MeCCNU) (200 mg/m2 orally every 6 weeks) (82 patients) or a combination of MeCCNU, chlorpromazine (50 mg/m2 im), and caffeine (600 mg/m2 sc) in the periumbilical area (75 patients)."9.05Randomized trial of chlorpromazine, caffeine, and methyl-CCNU in disseminated melanoma. ( Cohen, MH; Schoenfeld, D; Wolter, J, 1980)
"Sixteen patients with advanced colo-rectal cancer were treated with the combination methyl-CCNU, vincristin, 5-fluorouracil and streptozotocin (MOF-Strepto)."5.26[The combination methyl-CCNU, vincristine, 5-fluorouracil and streptozotocin in the treatment of advanced colo-rectal adenocarcinoma]. ( Cavalli, F; Sessa, C; Togni, P; Varini, M, 1982)
"One hundred and fifty-seven evaluable patients with advanced metastatic malignant melanoma were randomly assigned to receive either methyl-CCNU (MeCCNU) (200 mg/m2 orally every 6 weeks) (82 patients) or a combination of MeCCNU, chlorpromazine (50 mg/m2 im), and caffeine (600 mg/m2 sc) in the periumbilical area (75 patients)."5.05Randomized trial of chlorpromazine, caffeine, and methyl-CCNU in disseminated melanoma. ( Cohen, MH; Schoenfeld, D; Wolter, J, 1980)
" With the dosage and schedule we used, and in our patient population of largely elderly adults, THC therapy resulted in an overall more unpleasant treatment experience than that noted with prochlorperazine or placebo."2.65Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo. ( Creagan, ET; Frytak, S; Moertel, CG; O'Connell, MJ; O'Fallon, JR; Rubin, J; Schutt, AJ; Schwartau, NW, 1979)
"Sixteen patients with advanced colo-rectal cancer were treated with the combination methyl-CCNU, vincristin, 5-fluorouracil and streptozotocin (MOF-Strepto)."1.26[The combination methyl-CCNU, vincristine, 5-fluorouracil and streptozotocin in the treatment of advanced colo-rectal adenocarcinoma]. ( Cavalli, F; Sessa, C; Togni, P; Varini, M, 1982)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199011 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Togni, P1
Sessa, C1
Varini, M1
Cavalli, F1
Windschitl, H1
Scott, M1
Schutt, A1
McCormack, G1
Everson, L1
Cullinan, S1
Gerstner, J1
Krook, J1
Laurie, J1
Shreck, R1
Cohen, MH1
Schoenfeld, D1
Wolter, J1
McCracken, JD1
Ray, P1
Heilbrun, LK1
Vaitkevicius, VK1
Saiki, JH1
Rivkin, SE1
Rossof, AH1
Moore, TN1
Enck, RE1
Falkson, G1
Moertel, CG2
Lavin, P1
Pretorius, FJ1
Carbone, PP1
Frytak, S1
O'Fallon, JR1
Rubin, J1
Creagan, ET1
O'Connell, MJ1
Schutt, AJ2
Schwartau, NW1
Chang, P1
Levine, MA1
Wiernik, PH1
Walker, MD1
Cedermark, BJ1
Kaufman, JH1
Douglass, HO2
Mittelman, A1
Posey, LE1
Morgan, LR1
Engstrom, PF1
MacIntyre, JM1

Trials

9 trials available for semustine and Vomiting

ArticleYear
Randomized phase II studies in advanced colorectal carcinoma: a North Central Cancer Treatment Group study.
    Cancer treatment reports, 1983, Volume: 67, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Drug Evalu

1983
Randomized trial of chlorpromazine, caffeine, and methyl-CCNU in disseminated melanoma.
    Cancer treatment reports, 1980, Volume: 64, Issue:1

    Topics: Caffeine; Chlorpromazine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Melanoma; Nit

1980
5-Fluorouracil, methyl-CCNU, and radiotherapy with or without testolactone for localized adenocarcinoma of the exocrine pancreas: a Southwest Oncology Group Study.
    Cancer, 1980, Oct-01, Volume: 46, Issue:7

    Topics: Adenocarcinoma; Aged; Agranulocytosis; Anorexia; Antineoplastic Agents; Clinical Trials as Topic; Do

1980
Chemotherapy studies in primary liver cancer: a prospective randomized clinical trial.
    Cancer, 1978, Volume: 42, Issue:5

    Topics: Adenoma, Bile Duct; Antineoplastic Agents; Bone Marrow; Carcinoma, Hepatocellular; Clinical Trials a

1978
Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo.
    Annals of internal medicine, 1979, Volume: 91, Issue:6

    Topics: Adult; Aged; Antiemetics; Double-Blind Method; Dronabinol; Drug Evaluation; Fluorouracil; Gastrointe

1979
A phase II study of intravenously- administered methyl CCNU in the treatment of advanced sarcomas.
    Cancer, 1976, Volume: 37, Issue:2

    Topics: Clinical Trials as Topic; Drug Evaluation; Giant Cell Tumors; Humans; Infusions, Parenteral; Leiomyo

1976
Combination with 5-fluorouracil, methyl-CCNU and beta-2-deoxythioguanosine in advanced colo-rectal adenocarcinoma.
    Clinical oncology, 1977, Volume: 3, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Deoxyribonucleosides; Drug Therapy, Combination; Fem

1977
Methyl-CCNU versus methyl-CCNU and 5-fluorouracil in carcinoma of the large bowel.
    Cancer treatment reports, 1977, Volume: 61, Issue:8

    Topics: Arylsulfatases; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluo

1977
Chemotherapy of large bowel carcinoma--fluorouracil (FU) + hydroxyurea (HU) vs. methyl-CCNU, oncovin, fluorouracil, and streptozotocin (MOF-Strep). An Eastern Cooperative Oncology Group study.
    American journal of clinical oncology, 1985, Volume: 8, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorour

1985

Other Studies

2 other studies available for semustine and Vomiting

ArticleYear
[The combination methyl-CCNU, vincristine, 5-fluorouracil and streptozotocin in the treatment of advanced colo-rectal adenocarcinoma].
    Schweizerische medizinische Wochenschrift, 1982, Jun-26, Volume: 112, Issue:26

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Leu

1982
Mallory-Weiss lesion following cancer chemotherapy.
    Lancet (London, England), 1977, Oct-29, Volume: 2, Issue:8044

    Topics: Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Male; Mallory-Weiss Syndrome; Methy

1977