semustine has been researched along with Sarcoma in 5 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yap, BS | 1 |
| Benjamin, RS | 1 |
| Burgess, MA | 1 |
| Murphy, WK | 1 |
| Sinkovics, JG | 1 |
| Bodey, GP | 1 |
| Rivkin, SE | 1 |
| Gottlieb, JA | 1 |
| Thigpen, T | 1 |
| El Mawla, NG | 1 |
| Saiki, J | 1 |
| Dixon, DO | 1 |
| Omura, GA | 1 |
| Shingleton, HM | 1 |
| Creasman, WT | 1 |
| Blessing, JA | 1 |
| Boronow, RC | 1 |
| Chang, P | 1 |
| Levine, MA | 1 |
| Wiernik, PH | 1 |
| Walker, MD | 1 |
| Slavik, M | 1 |
2 trials available for semustine and Sarcoma
| Article | Year |
|---|---|
Chemotherapy of gynecologic cancer with nitrosoureas: a randomized trial of CCNU and methyl-CCNU in cancers of the cervix, corpus, vagina, and vulva.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Genital Neoplasms, Femal | 1978 |
A phase II study of intravenously- administered methyl CCNU in the treatment of advanced sarcomas.
Topics: Clinical Trials as Topic; Drug Evaluation; Giant Cell Tumors; Humans; Infusions, Parenteral; Leiomyo | 1976 |
3 other studies available for semustine and Sarcoma
| Article | Year |
|---|---|
A phase II evaluation of methyl CCNU and actinomycin D in the treatment of advanced sarcomas in adults.
Topics: Adult; Aged; Bone Neoplasms; Dactinomycin; Drug Administration Schedule; Drug Evaluation; Drug Thera | 1981 |
Methyl CCNU and adriamycin for patients with metastatic sarcomas: a Southwest Oncology Group study.
Topics: Age Factors; Bone Neoplasms; Doxorubicin; Drug Therapy, Combination; Gastrointestinal Diseases; Huma | 1980 |
Clinical studies with nitrosoureas in various solid tumors.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Carmustine; Female; Genital Neoplasms, F | 1976 |