semustine has been researched along with Pulmonary Fibrosis in 3 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pulmonary fibrosis is a serious side effect of nitrosourea therapy, occurring most frequently in patients treated with BCNU." | 1.28 | Pulmonary fibrosis associated with low-dose adjuvant methyl-CCNU. ( Block, M; Hirschl, S; Lachowiez, RM; Rios, C, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, W | 1 |
| Moore, RP | 1 |
| Wampler, GL | 1 |
| Massin, F | 1 |
| Coudert, B | 1 |
| Foucher, P | 1 |
| Lombard, JN | 1 |
| Reybet-Degat, O | 1 |
| Jeannin, L | 1 |
| Camus, P | 1 |
| Block, M | 1 |
| Lachowiez, RM | 1 |
| Rios, C | 1 |
| Hirschl, S | 1 |
1 review available for semustine and Pulmonary Fibrosis
| Article | Year |
|---|---|
[Nitrosourea-induced lung diseases].
Topics: Adult; Brain Neoplasms; Carmustine; Child; Drug Therapy, Combination; Female; Humans; Iatrogenic Dis | 1992 |
2 other studies available for semustine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Interstitial pulmonary fibrosis as a complication of prolonged methyl-CCNU therapy.
Topics: Brain Neoplasms; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Pu | 1978 |
Pulmonary fibrosis associated with low-dose adjuvant methyl-CCNU.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Humans; Male; Middle Aged | 1990 |