semustine has been researched along with Kidney Diseases in 11 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Semustine is an investigational cancer chemotherapeutic agent in widespread use." | 2.36 | Nephrotoxicity of semustine. ( Boyd, MR; Kramer, RA; Posada, JG; Weiss, RB, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harrison, SD | 1 |
| Cox, JL | 1 |
| Giles, RC | 1 |
| Goldberg, ID | 1 |
| Garnick, MB | 1 |
| Bloomer, WD | 1 |
| Weiss, RB | 1 |
| Posada, JG | 1 |
| Kramer, RA | 2 |
| Boyd, MR | 2 |
| Antonovych, TT | 1 |
| Dumler, F | 1 |
| Schacht, RG | 1 |
| Feiner, HD | 1 |
| Gallo, GR | 1 |
| Lieberman, A | 1 |
| Baldwin, DS | 1 |
| Ercan, MT | 1 |
| Or, IS | 1 |
| Bekdik, CF | 1 |
| Sarizi, T | 1 |
| Yazicioglu, A | 1 |
| Cachat, F | 1 |
| Guignard, JP | 1 |
| Nichols, WC | 1 |
| Moertel, CG | 1 |
| Engstrom, PF | 1 |
| MacIntyre, JM | 1 |
| Schutt, AJ | 1 |
| Douglass, HO | 1 |
| Dees, JH | 1 |
4 reviews available for semustine and Kidney Diseases
| Article | Year |
|---|---|
Urinary tract toxic effects of cancer therapy.
Topics: Antineoplastic Agents; Cisplatin; Combined Modality Therapy; Cystitis; Humans; Kidney; Kidney Diseas | 1984 |
Nephrotoxicity of semustine.
Topics: Animals; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Humans; Kidney Diseases; N | 1983 |
Drug-induced nephropathies.
Topics: Allopurinol; Aminoglycosides; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Captopril | 1984 |
[The kidney in children under chemotherapy].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Child; Cisplatin; Glomerular | 1996 |
1 trial available for semustine and Kidney Diseases
| Article | Year |
|---|---|
Chemotherapy of large bowel carcinoma--fluorouracil (FU) + hydroxyurea (HU) vs. methyl-CCNU, oncovin, fluorouracil, and streptozotocin (MOF-Strep). An Eastern Cooperative Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorour | 1985 |
6 other studies available for semustine and Kidney Diseases
| Article | Year |
|---|---|
Effects of prochlorperazine on experimental nephrotoxicity.
Topics: Animals; Body Weight; Kidney Diseases; Male; Mercuric Chloride; Mercury; Mice; Mice, Inbred Strains; | 1982 |
Drug-induced glomerulopathy: a selective review.
Topics: Anti-Inflammatory Agents; Captopril; Child; Gold; Humans; Kidney Diseases; Mitomycin; Mitomycins; Pe | 1983 |
Nephrotoxicity of nitrosoureas.
Topics: Adolescent; Adult; Aged; Biopsy; Blood Urea Nitrogen; Brain Neoplasms; Carmustine; Child; Creatinine | 1981 |
99mTc-methyl-CCNU for the static imaging of kidneys.
Topics: Animals; Humans; Kidney; Kidney Cortex; Kidney Diseases; Mice; Nitrosourea Compounds; Rabbits; Radia | 1980 |
Nephrotoxicity of methyl-CCNU.
Topics: Drug Therapy, Combination; Female; Humans; Kidney Diseases; Nitrosourea Compounds; Semustine | 1979 |
Comparative nephrotoxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU) and chlorozotocin: functional-structural correlations in the Fischer 344 rat.
Topics: Animals; Blood Urea Nitrogen; Glucose; Injections, Subcutaneous; Kidney Diseases; Kidney Papillary N | 1986 |