semustine has been researched along with Experimental Leukemia in 9 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Piperidino-CNU and Ethylmethanesulfonato-CNU also effected cures; however, only Piperidino-CNU in one dosage effected a median survival time of greater than 90 days." | 1.26 | Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222. ( Eisenbrand, G; Fiebig, HH; Zeller, WJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crider, AM | 1 |
| Lamey, R | 1 |
| Floss, HG | 1 |
| Cassady, JM | 1 |
| Bradner, WJ | 1 |
| Komiyama, K | 1 |
| Edanami, K | 1 |
| Kuroda, T | 1 |
| Umezawa, I | 1 |
| Peled, A | 1 |
| Perk, K | 2 |
| Haran-Ghera, N | 1 |
| Chirigos, MA | 1 |
| Zeller, WJ | 2 |
| Berger, M | 1 |
| Klein, DL | 2 |
| Cote, P | 1 |
| Garner, W | 1 |
| Wallen, RM | 1 |
| Pearson, JW | 2 |
| Sbaraglia, G | 1 |
| Cenci, E | 1 |
| Vecchiarelli, A | 1 |
| Perito, S | 1 |
| Dahlberg, JE | 1 |
| Brown, W | 1 |
| Eisenbrand, G | 1 |
| Fiebig, HH | 1 |
| Bekesi, JG | 1 |
| Roboz, JP | 1 |
| Zimmerman, E | 1 |
| Holland, JF | 1 |
9 other studies available for semustine and Experimental Leukemia
| Article | Year |
|---|---|
Synthesis of nitrosourea derivatives of pyridine and piperidine as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Leukemia, Experimental; Leukopenia; Mice; Neoplasms, Experimental; N | 1980 |
Antitumor effect of 3-[3-(2-chloroethyl)-3-nitrosoureido]-3-deoxy-D-glucopyranose on murine tumors.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Leukemia, Experimental; Leukocyte Cou | 1981 |
The oncostatic effect of methyl-CCNU on various experimental lymphoreticular neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Cell Count; Body Weight; Drug Administration Schedu | 1982 |
[Combination chemotherapy of transplanted rat leukemia L 5222 with 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and cyclophosphamide (CPA) as well as with methyl-CCNU and CPA (author's transl)].
Topics: Animals; Cyclophosphamide; Drug Therapy, Combination; Leukemia, Experimental; Lomustine; Male; Neopl | 1981 |
The use of immunotherapy to enhance tumor rejection immunity in leukemic (L2C) guinea pigs following remission induction with MeCCNU.
Topics: Animals; BCG Vaccine; Bone Marrow; Cell Migration Inhibition; Female; Graft Rejection; Guinea Pigs; | 1980 |
[Use of BCG as an immunoadjuvant in combination with antitumor agents in virus-induced leukemia].
Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carmustine; Drug Synergism; Drug Therapy, Combination; | 1980 |
Isolation and characterization of a spontaneous lymphocytic leukemia (L-76) in the strain 2 guinea pig.
Topics: Animals; Antigens, Neoplasm; Chromosome Aberrations; Cyclophosphamide; Female; Guinea Pigs; Histocom | 1978 |
Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222.
Topics: Animals; Carmustine; Drug Evaluation, Preclinical; Female; Leukemia, Experimental; Lomustine; Male; | 1979 |
Treatment of spontaneous leukemia in AKR mice with chemotherapy, immunotherapy, or interferon.
Topics: AKR murine leukemia virus; Animals; Antibodies, Viral; Antigens, Neoplasm; Antineoplastic Agents; Dr | 1976 |