semustine has been researched along with Colorectal Neoplasms in 8 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metastatic colorectal cancer is generally incurable." | 6.68 | Randomized phase III study of 5-fluorouracil plus high dose folinic acid versus 5-fluorouracil plus folinic acid plus methyl-lomustine for patients with advanced colorectal cancer. ( Abbruzzese, JL; Brown, BW; Gross, HM; Jones, DV; Levin, B; Levy, LB; Pendergrass, KB; Pugh, RP; Wade, JL; Winn, RJ, 1995) |
| "Metastatic colorectal cancer is generally incurable." | 2.68 | Randomized phase III study of 5-fluorouracil plus high dose folinic acid versus 5-fluorouracil plus folinic acid plus methyl-lomustine for patients with advanced colorectal cancer. ( Abbruzzese, JL; Brown, BW; Gross, HM; Jones, DV; Levin, B; Levy, LB; Pendergrass, KB; Pugh, RP; Wade, JL; Winn, RJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, DV | 1 |
| Winn, RJ | 1 |
| Brown, BW | 1 |
| Levy, LB | 1 |
| Pugh, RP | 1 |
| Wade, JL | 1 |
| Gross, HM | 1 |
| Pendergrass, KB | 1 |
| Levin, B | 2 |
| Abbruzzese, JL | 2 |
| Kodaira, S | 1 |
| Shatari, T | 1 |
| Nozawa, K | 1 |
| Wagener, DJ | 1 |
| Wils, JA | 1 |
| Bécouarn, Y | 1 |
| Brunet, R | 1 |
| Ravaud, A | 1 |
| Bussières, E | 1 |
| Lagarde, P | 1 |
| Weeks, A | 1 |
| Raber, MN | 1 |
| Gravel, D | 1 |
| DuBrow, RA | 1 |
| Grem, J | 1 |
| Chun, HG | 1 |
| Macdonald, JS | 1 |
| Glimelius, B | 1 |
| Påhlman, L | 1 |
| Taylor, I | 1 |
5 reviews available for semustine and Colorectal Neoplasms
| Article | Year |
|---|---|
[Recent advances is surgical adjuvant chemotherapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug A | 2000 |
[Systemic chemotherapy in metastatic colorectal adenocarcinomas].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Fem | 1992 |
Adjuvant therapy of colorectal cancer: where do we stand?
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Hum | 1989 |
Cytostatic drug therapy in disseminated colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Col | 1988 |
Adjuvant cytotoxic chemotherapy for colorectal cancer: the present position.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combine | 1988 |
2 trials available for semustine and Colorectal Neoplasms
| Article | Year |
|---|---|
Randomized phase III study of 5-fluorouracil plus high dose folinic acid versus 5-fluorouracil plus folinic acid plus methyl-lomustine for patients with advanced colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms | 1995 |
Cytostatic drug therapy in disseminated colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Col | 1988 |
2 other studies available for semustine and Colorectal Neoplasms
| Article | Year |
|---|---|
[Adjuvant treatment of rectal carcinoma: also a step forward?].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal | 1992 |
Phase I trial of semustine plus weekly fluorouracil and high-dose leucovorin calcium in patients with advanced colorectal cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Evaluatio | 1989 |