semustine has been researched along with Chronic Kidney Failure in 2 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The nephrotoxicity of semustine (methyl-CCNU) has been studied in 45 adult patients with surgically resected Stage I or II malignant melanoma who received this drug as adjuvant chemotherapy." | 9.05 | Nephrotoxicity of semustine (methyl-CCNU) in patients with malignant melanoma receiving adjuvant chemotherapy. ( Fisher, RI; Jensen-Akula, M; Mandard, JC; Micetich, KC, 1981) |
| "The nephrotoxicity of semustine (methyl-CCNU) has been studied in 45 adult patients with surgically resected Stage I or II malignant melanoma who received this drug as adjuvant chemotherapy." | 5.05 | Nephrotoxicity of semustine (methyl-CCNU) in patients with malignant melanoma receiving adjuvant chemotherapy. ( Fisher, RI; Jensen-Akula, M; Mandard, JC; Micetich, KC, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Micetich, KC | 1 |
| Jensen-Akula, M | 1 |
| Mandard, JC | 1 |
| Fisher, RI | 1 |
| Harmon, WE | 1 |
| Cohen, HJ | 1 |
| Schneeberger, EE | 1 |
| Grupe, WE | 1 |
1 trial available for semustine and Chronic Kidney Failure
| Article | Year |
|---|---|
Nephrotoxicity of semustine (methyl-CCNU) in patients with malignant melanoma receiving adjuvant chemotherapy.
Topics: Adolescent; Adult; Aged; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Humans; Kidney; | 1981 |
1 other study available for semustine and Chronic Kidney Failure
| Article | Year |
|---|---|
Chronic renal failure in children treated with methyl CCNU.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Humans; Kidney; Kidney Failure, Chronic; Nitro | 1979 |