Page last updated: 2024-11-04

semustine and Carcinoma, Squamous Cell

semustine has been researched along with Carcinoma, Squamous Cell in 12 studies

Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.

Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" The addition of a nitrosourea appears to be an improvement over cyclophosphamide used alone in oat cell carcinoma and over the two drug combination of cyclophosphamide and methotrexate in both adenocarcinoma of the lung and oat cell disease."5.04Nitrosourea combinations in lung cancer. ( Livingston, RB, 1976)
"Twenty-two patients had squamous carcinoma and 1 had adenosquamous carcinoma."1.27Methyl-CCNU, doxorubicin, and cis-diamminedichloroplatinum II in the management of recurrent and metastatic squamous carcinoma of the cervix. ( Allegra, JC; Carlson, JA; Day, TG; Greenberg, RA; Masterson, BJ; Woodcock, TM, 1984)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Franco, P1
Mistrangelo, M1
Arcadipane, F1
Munoz, F1
Sciacero, P1
Spadi, R1
Migliaccio, F1
Angelini, V1
Bombaci, S1
Rondi, N1
Numico, G1
Ragona, R1
Cassoni, P1
Morino, M1
Racca, P1
Ricardi, U1
Carlson, JA1
Day, TG2
Allegra, JC1
Woodcock, TM1
Greenberg, RA1
Masterson, BJ1
Livingston, RB3
Einhorn, LH2
Bodey, GP2
Burgess, MA2
Freireich, EJ1
Gottlieb, JA3
McMahon, LJ1
Jones, SE1
Durie, BG1
Salmon, SE1
Lagakos, SW1
Gutierrez, AC1
Wilson, HE1
Selawry, OS1
Omura, GA1
Shingleton, HM1
Creasman, WT1
Blessing, JA1
Boronow, RC1
Wharton, JT1
Rutledge, FN1
Slavik, M2
Ushio, Y1
Arita, N1
Hayakawa, T1
Mogami, H1
Hasegawa, H1
Bitoh, S1
Oku, Y1
Ikeda, H1
Kanai, N1
Kanoh, M1
Wasserman, TH1
Carter, SK1

Reviews

1 review available for semustine and Carcinoma, Squamous Cell

ArticleYear
Methyl-CCNU inclinical cancer therapy.
    Cancer treatment reviews, 1974, Volume: 1, Issue:4

    Topics: Animals; Astrocytoma; Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous

1974

Trials

5 trials available for semustine and Carcinoma, Squamous Cell

ArticleYear
Intensity-modulated radiation therapy with simultaneous integrated boost combined with concurrent chemotherapy for the treatment of anal cancer patients: 4-year results of a consecutive case series.
    Cancer investigation, 2015, Volume: 33, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2015
Therapy of advanced squamous carcinoma of the lung: cyclophosphamide vesus "COMB".
    Cancer, 1977, Volume: 39, Issue:3

    Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Co

1977
Nitrosourea combinations in lung cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topi

1976
Chemotherapy of gynecologic cancer with nitrosoureas: a randomized trial of CCNU and methyl-CCNU in cancers of the cervix, corpus, vagina, and vulva.
    Cancer treatment reports, 1978, Volume: 62, Issue:5

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Genital Neoplasms, Femal

1978
Chemotherapy of brain metastases from lung carcinoma: a controlled randomized study.
    Neurosurgery, 1991, Volume: 28, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Carcinom

1991

Other Studies

6 other studies available for semustine and Carcinoma, Squamous Cell

ArticleYear
Methyl-CCNU, doxorubicin, and cis-diamminedichloroplatinum II in the management of recurrent and metastatic squamous carcinoma of the cervix.
    Cancer, 1984, Jul-15, Volume: 54, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Do

1984
COMB (cyclophosphamide, oncovin, methyl-CCNU, and bleomycin): a four-drug combination in solid tumors.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Evaluation; Drug

1975
Sequential combination chemotherapy for advanced, recurrent, squamous carcinoma of the head and neck.
    Cancer treatment reports, 1976, Volume: 60, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubic

1976
Combination chemotherapy with methyl-CCNU (NSC-95441), cyclophosphamide (NSC-26271), vincristine (NSC-67574), methotrexate (NSC-740), and bleomycin (NSC-125066) in advanced bronchogenic carcinoma.
    Cancer letters, 1975, Volume: 1, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Ca

1975
Chemotherapy for squamous carcinoma of the cervix: doxorubicin--methyl CCNU.
    American journal of obstetrics and gynecology, 1978, Nov-01, Volume: 132, Issue:5

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Female; Humans; Middl

1978
Clinical studies with nitrosoureas in various solid tumors.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Carmustine; Female; Genital Neoplasms, F

1976