semustine has been researched along with Carcinoma, Squamous Cell in 12 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The addition of a nitrosourea appears to be an improvement over cyclophosphamide used alone in oat cell carcinoma and over the two drug combination of cyclophosphamide and methotrexate in both adenocarcinoma of the lung and oat cell disease." | 5.04 | Nitrosourea combinations in lung cancer. ( Livingston, RB, 1976) |
| "Twenty-two patients had squamous carcinoma and 1 had adenosquamous carcinoma." | 1.27 | Methyl-CCNU, doxorubicin, and cis-diamminedichloroplatinum II in the management of recurrent and metastatic squamous carcinoma of the cervix. ( Allegra, JC; Carlson, JA; Day, TG; Greenberg, RA; Masterson, BJ; Woodcock, TM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franco, P | 1 |
| Mistrangelo, M | 1 |
| Arcadipane, F | 1 |
| Munoz, F | 1 |
| Sciacero, P | 1 |
| Spadi, R | 1 |
| Migliaccio, F | 1 |
| Angelini, V | 1 |
| Bombaci, S | 1 |
| Rondi, N | 1 |
| Numico, G | 1 |
| Ragona, R | 1 |
| Cassoni, P | 1 |
| Morino, M | 1 |
| Racca, P | 1 |
| Ricardi, U | 1 |
| Carlson, JA | 1 |
| Day, TG | 2 |
| Allegra, JC | 1 |
| Woodcock, TM | 1 |
| Greenberg, RA | 1 |
| Masterson, BJ | 1 |
| Livingston, RB | 3 |
| Einhorn, LH | 2 |
| Bodey, GP | 2 |
| Burgess, MA | 2 |
| Freireich, EJ | 1 |
| Gottlieb, JA | 3 |
| McMahon, LJ | 1 |
| Jones, SE | 1 |
| Durie, BG | 1 |
| Salmon, SE | 1 |
| Lagakos, SW | 1 |
| Gutierrez, AC | 1 |
| Wilson, HE | 1 |
| Selawry, OS | 1 |
| Omura, GA | 1 |
| Shingleton, HM | 1 |
| Creasman, WT | 1 |
| Blessing, JA | 1 |
| Boronow, RC | 1 |
| Wharton, JT | 1 |
| Rutledge, FN | 1 |
| Slavik, M | 2 |
| Ushio, Y | 1 |
| Arita, N | 1 |
| Hayakawa, T | 1 |
| Mogami, H | 1 |
| Hasegawa, H | 1 |
| Bitoh, S | 1 |
| Oku, Y | 1 |
| Ikeda, H | 1 |
| Kanai, N | 1 |
| Kanoh, M | 1 |
| Wasserman, TH | 1 |
| Carter, SK | 1 |
1 review available for semustine and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Methyl-CCNU inclinical cancer therapy.
Topics: Animals; Astrocytoma; Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous | 1974 |
5 trials available for semustine and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Intensity-modulated radiation therapy with simultaneous integrated boost combined with concurrent chemotherapy for the treatment of anal cancer patients: 4-year results of a consecutive case series.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel | 2015 |
Therapy of advanced squamous carcinoma of the lung: cyclophosphamide vesus "COMB".
Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Co | 1977 |
Nitrosourea combinations in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topi | 1976 |
Chemotherapy of gynecologic cancer with nitrosoureas: a randomized trial of CCNU and methyl-CCNU in cancers of the cervix, corpus, vagina, and vulva.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Genital Neoplasms, Femal | 1978 |
Chemotherapy of brain metastases from lung carcinoma: a controlled randomized study.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Carcinom | 1991 |
6 other studies available for semustine and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Methyl-CCNU, doxorubicin, and cis-diamminedichloroplatinum II in the management of recurrent and metastatic squamous carcinoma of the cervix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Do | 1984 |
COMB (cyclophosphamide, oncovin, methyl-CCNU, and bleomycin): a four-drug combination in solid tumors.
Topics: Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Evaluation; Drug | 1975 |
Sequential combination chemotherapy for advanced, recurrent, squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubic | 1976 |
Combination chemotherapy with methyl-CCNU (NSC-95441), cyclophosphamide (NSC-26271), vincristine (NSC-67574), methotrexate (NSC-740), and bleomycin (NSC-125066) in advanced bronchogenic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Ca | 1975 |
Chemotherapy for squamous carcinoma of the cervix: doxorubicin--methyl CCNU.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Female; Humans; Middl | 1978 |
Clinical studies with nitrosoureas in various solid tumors.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Carmustine; Female; Genital Neoplasms, F | 1976 |