semustine has been researched along with Carcinoma, Oat Cell in 7 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The addition of a nitrosourea appears to be an improvement over cyclophosphamide used alone in oat cell carcinoma and over the two drug combination of cyclophosphamide and methotrexate in both adenocarcinoma of the lung and oat cell disease." | 5.04 | Nitrosourea combinations in lung cancer. ( Livingston, RB, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brandman, JR | 1 |
| Ruckdeschel, JC | 2 |
| O'Donnell, MR | 2 |
| Horton, J | 2 |
| Berman, R | 1 |
| Steel, GG | 1 |
| Livingston, RB | 2 |
| Einhorn, LH | 1 |
| Bodey, GP | 1 |
| Burgess, MA | 1 |
| Freireich, EJ | 1 |
| Gottlieb, JA | 1 |
| McMahon, LJ | 1 |
| Jones, SE | 1 |
| Durie, BG | 1 |
| Salmon, SE | 1 |
| Baxter, D | 1 |
| McKneally, MF | 1 |
| Caradonna, R | 1 |
| Wasserman, TH | 1 |
| Slavik, M | 1 |
| Carter, SK | 1 |
1 review available for semustine and Carcinoma, Oat Cell
| Article | Year |
|---|---|
Methyl-CCNU inclinical cancer therapy.
Topics: Animals; Astrocytoma; Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous | 1974 |
2 trials available for semustine and Carcinoma, Oat Cell
| Article | Year |
|---|---|
Nitrosourea combinations in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topi | 1976 |
Intensive induction chemotherapy for small cell anaplastic carcinoma of the lung.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topi | 1985 |
4 other studies available for semustine and Carcinoma, Oat Cell
| Article | Year |
|---|---|
Small cell cancer of lung; rapid tumor necrosis leading to serious pulmonary infections after intensive chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Empyema; | 1981 |
Induced and inherent resistance to alkylating agents in human small-cell bronchial carcinoma xenografts.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Drug Res | 1984 |
COMB (cyclophosphamide, oncovin, methyl-CCNU, and bleomycin): a four-drug combination in solid tumors.
Topics: Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Evaluation; Drug | 1975 |
Combination chemotherapy with methyl-CCNU (NSC-95441), cyclophosphamide (NSC-26271), vincristine (NSC-67574), methotrexate (NSC-740), and bleomycin (NSC-125066) in advanced bronchogenic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Ca | 1975 |