semustine has been researched along with Cancer of Skin in 9 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred twenty-two patients with disseminated malignant melanoma were randomized using an unbalanced randomization to receive chlorozotocin, neocarzinostatin, or MeCCNU." | 7.67 | Randomized trial of chlorozotocin, neocarzinostatin, or methyl-CCNU in patients with malignant melanoma. ( Amato, DA; Cunningham, TJ; Falkson, G; Kaufman, JH; Von Hoff, DD, 1984) |
| "Twenty-six patients with disseminated malignant melanoma received an oral regimen of mitolactol and semustine (methyl-CCNU)." | 7.66 | Phase II study of mitolactol and semustine combination chemotherapy for advanced malignant melanoma. ( Ahmann, DL; Creagan, ET; Green, SJ; Schutt, AJ, 1982) |
| "One hundred twenty-two patients with disseminated malignant melanoma were randomized using an unbalanced randomization to receive chlorozotocin, neocarzinostatin, or MeCCNU." | 3.67 | Randomized trial of chlorozotocin, neocarzinostatin, or methyl-CCNU in patients with malignant melanoma. ( Amato, DA; Cunningham, TJ; Falkson, G; Kaufman, JH; Von Hoff, DD, 1984) |
| "Twenty-six patients with disseminated malignant melanoma received an oral regimen of mitolactol and semustine (methyl-CCNU)." | 3.66 | Phase II study of mitolactol and semustine combination chemotherapy for advanced malignant melanoma. ( Ahmann, DL; Creagan, ET; Green, SJ; Schutt, AJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weltz, MD | 1 |
| Perry, DJ | 1 |
| Blom, J | 1 |
| Butler, WM | 1 |
| Von Hoff, DD | 1 |
| Amato, DA | 1 |
| Kaufman, JH | 1 |
| Falkson, G | 1 |
| Cunningham, TJ | 1 |
| Fisher, RI | 1 |
| Terry, WD | 1 |
| Hodes, RJ | 1 |
| Rosenberg, SA | 1 |
| Makuch, R | 1 |
| Gordon, HG | 1 |
| Fisher, SG | 1 |
| Knost, JA | 1 |
| Reynolds, V | 1 |
| Greco, FA | 1 |
| Oldham, RK | 1 |
| Creagan, ET | 1 |
| Ahmann, DL | 1 |
| Schutt, AJ | 1 |
| Green, SJ | 1 |
| Tsukagoshi, S | 1 |
| Twentyman, PR | 1 |
| Luce, JK | 1 |
| Takahashi, T | 1 |
2 reviews available for semustine and Cancer of Skin
| Article | Year |
|---|---|
[Fundamental studies on the surgical adjuvant chemotherapy to support the clinical efficacies].
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast N | 1997 |
Emulsion and activated carbon in cancer chemotherapy.
Topics: Administration, Oral; Adult; Aged; Animals; Bleomycin; Breast Neoplasms; Carbon; Clinical Trials as | 1986 |
4 trials available for semustine and Cancer of Skin
| Article | Year |
|---|---|
Methyl-CCNU, 5-fluorouracil, vincristine, and streptozocin (MOF-STREP) in metastatic colo-rectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Clinical Trials as Topi | 1983 |
Adjuvant immunotherapy or chemotherapy for malignant melanoma. Preliminary report of the National Cancer Institute randomized clinical trial.
Topics: BCG Vaccine; Cell Line; Clinical Trials as Topic; Female; Humans; Male; Melanoma; Mitomycins; Neopla | 1981 |
Adjuvant chemoimmunotherapy stage I/II malignant melanoma.
Topics: Adolescent; Adult; Aged; BCG Vaccine; Clinical Trials as Topic; Dacarbazine; Female; Humans; Lymph N | 1982 |
Emulsion and activated carbon in cancer chemotherapy.
Topics: Administration, Oral; Adult; Aged; Animals; Bleomycin; Breast Neoplasms; Carbon; Clinical Trials as | 1986 |
4 other studies available for semustine and Cancer of Skin
| Article | Year |
|---|---|
Randomized trial of chlorozotocin, neocarzinostatin, or methyl-CCNU in patients with malignant melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis | 1984 |
Phase II study of mitolactol and semustine combination chemotherapy for advanced malignant melanoma.
Topics: Aged; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukocyte Count; Leukopenia; Male; | 1982 |
Sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea of the EMT6 tumor in vivo as determined by both tumor volume response and in vitro plating assay.
Topics: Animals; Carmustine; Cell Count; Cell Cycle; Cell Survival; Clone Cells; Lung Neoplasms; Male; Mamma | 1978 |
Chemotherapy of melanoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carmustine; Cyclophosphamide; D | 1975 |