semustine has been researched along with Astrocytoma, Grade IV in 8 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and safety of temozolomide (TMZ) versus semustine (Me-CCNU) in the treatment of recurrent glioblastoma multiforme (GBM) or anaplastic astrocytoma (AA)." | 9.17 | [Multicenter randomized controlled study of temozolomide versus semustine in the treatment of recurrent malignant glioma]. ( Sun, J; Yang, SY; Yang, XJ, 2013) |
| "To evaluate the efficacy and safety of temozolomide (TMZ) versus semustine (Me-CCNU) in the treatment of recurrent glioblastoma multiforme (GBM) or anaplastic astrocytoma (AA)." | 5.17 | [Multicenter randomized controlled study of temozolomide versus semustine in the treatment of recurrent malignant glioma]. ( Sun, J; Yang, SY; Yang, XJ, 2013) |
| "Four who had nonirradiated anaplastic astrocytomas all responded and survived for 38+ to 48." | 1.27 | Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and systemic chemotherapy for malignant gliomas: a follow-up study. ( Avellanosa, AM; Barua, NR; Hong, CI; Patel, A; West, CR, 1983) |
| "Seven human brain tumors were transplanted into the brains (6/7 takes) and subcutaneous tissues (7/7 takes) of athymic nude mice." | 1.26 | Human brain tumor transplantation into nude mice. ( Basler, GA; Chernik, NL; Posner, JB; Shapiro, WR, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, J | 1 |
| Yang, XJ | 1 |
| Yang, SY | 1 |
| Zhao, Z | 1 |
| Liu, Y | 1 |
| He, H | 1 |
| Chen, X | 1 |
| Chen, J | 1 |
| Lu, YC | 1 |
| Kobiakov, GL | 1 |
| West, CR | 2 |
| Avellanosa, AM | 2 |
| Barua, NR | 1 |
| Patel, A | 1 |
| Hong, CI | 1 |
| Walker, MD | 1 |
| Shapiro, WR | 1 |
| Basler, GA | 1 |
| Chernik, NL | 1 |
| Posner, JB | 1 |
| Monfardini, S | 1 |
| Brambilla, C | 1 |
| Solero, CL | 1 |
| Vaghi, A | 1 |
| Valagussa, P | 1 |
| Morello, G | 1 |
| Bonadonna, G | 1 |
| Tsukada, Y | 1 |
| Higby, DJ | 1 |
| Bakshi, S | 1 |
| Reese, PA | 1 |
| Jennings, E | 1 |
2 reviews available for semustine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
[Clinical significance of mustoforan in management of malignant glioma].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barr | 2007 |
Treatment of brain tumors.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Divis | 1977 |
2 trials available for semustine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
[Multicenter randomized controlled study of temozolomide versus semustine in the treatment of recurrent malignant glioma].
Topics: Adult; Astrocytoma; Dacarbazine; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Neoplasm R | 2013 |
Treatment of brain tumors.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Divis | 1977 |
5 other studies available for semustine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Candidate genes influencing sensitivity and resistance of human glioblastoma to Semustine.
Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Computational Biology; Dat | 2011 |
Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and systemic chemotherapy for malignant gliomas: a follow-up study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin | 1983 |
Human brain tumor transplantation into nude mice.
Topics: Animals; Brain Neoplasms; Carmustine; Glioblastoma; Humans; Mice; Mice, Nude; Neoplasm Transplantati | 1979 |
Adjuvant chemotherapy with nitrosourea compounds following surgery plus radiotherapy in glioblastoma multiforme.
Topics: Brain Neoplasms; Carmustine; Glioblastoma; Humans; Lomustine; Nitrosourea Compounds; Semustine | 1978 |
Chemotherapy of nonirradiated malignant gliomas. Phase II: study of the combination of methyl-CCNU, vincristine, and procarbazine.
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Brain Neoplasms; Drug Evaluation; Drug Therapy, Com | 1979 |