semustine has been researched along with Abnormalities, Autosome in 3 studies
Semustine: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
semustine : An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Induction of chromosome aberrations and sister chromatid exchange frequency had shown dose-effect relationship." | 1.27 | Genotoxic effects of MeCCNU on human peripheral blood lymphocytes. ( Adhvaryu, SG; Shah, VC; Vyas, RC, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klein, DL | 1 |
| Perk, K | 1 |
| Dahlberg, JE | 1 |
| Brown, W | 1 |
| Pearson, JW | 1 |
| Vyas, RC | 2 |
| Adhvaryu, SG | 2 |
| Shah, VC | 2 |
3 other studies available for semustine and Abnormalities, Autosome
| Article | Year |
|---|---|
Isolation and characterization of a spontaneous lymphocytic leukemia (L-76) in the strain 2 guinea pig.
Topics: Animals; Antigens, Neoplasm; Chromosome Aberrations; Cyclophosphamide; Female; Guinea Pigs; Histocom | 1978 |
Genotoxic effects of MeCCNU on human peripheral blood lymphocytes.
Topics: Administration, Oral; Adult; Chromosome Aberrations; Humans; In Vitro Techniques; Lymphocytes; Mitot | 1988 |
Cytogenetic effects of Me-CCNU on sister chromatid exchange frequency, cellular kinetics and chromosome aberrations.
Topics: Animals; Cell Cycle; Chromosome Aberrations; Cricetinae; Cricetulus; Dimethyl Sulfoxide; Female; Met | 1986 |