selinexor and Nerve-Sheath-Neoplasms

selinexor has been researched along with Nerve-Sheath-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for selinexor and Nerve-Sheath-Neoplasms

Article	Year
Selinexor, a First in Class, Nuclear Export Inhibitor for the Treatment of Advanced Malignant Peripheral Nerve Sheath Tumor. The oncologist, 2021, Volume: 26, Issue:4 Malignant peripheral nerve sheath tumor (MPNST) is a highly malignant neoplasm arising from peripheral nerve or its attendant sheath and is derived from Schwann or pluripotent cells of neural crest origin. Patients with recurrent, unresectable, or advanced stage disease have limited treatment options, and current therapies are associated with little benefit. In this article, we report nine cases of MPNST treated with selinexor, an orally bioavailable, selective inhibitor of nuclear export, accompanied by tumor stabilization or regression. Topics: Active Transport, Cell Nucleus; Humans; Hydrazines; Nerve Sheath Neoplasms; Neurofibrosarcoma; Triazoles	2021

Article

Year

Selinexor, a First in Class, Nuclear Export Inhibitor for the Treatment of Advanced Malignant Peripheral Nerve Sheath Tumor.

The oncologist, 2021, Volume: 26, Issue:4

Malignant peripheral nerve sheath tumor (MPNST) is a highly malignant neoplasm arising from peripheral nerve or its attendant sheath and is derived from Schwann or pluripotent cells of neural crest origin. Patients with recurrent, unresectable, or advanced stage disease have limited treatment options, and current therapies are associated with little benefit. In this article, we report nine cases of MPNST treated with selinexor, an orally bioavailable, selective inhibitor of nuclear export, accompanied by tumor stabilization or regression.

Topics: Active Transport, Cell Nucleus; Humans; Hydrazines; Nerve Sheath Neoplasms; Neurofibrosarcoma; Triazoles

2021