Page last updated: 2024-08-25

selfotel and Brain Ischemia

selfotel has been researched along with Brain Ischemia in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (89.47)	18.2507
2000's	2 (10.53)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Craddock, SD; Holtz, ML; Minger, SL; Pettigrew, LC	1
Barber, PA; Buchan, AM; Hill, MD; Hoyte, L	1
Kanthan, R; Shuaib, A; Waqar, T; Wishart, T	1
Hakim, AM; Hogan, MJ; Takizawa, S	1
Giffard, RG; Maier, CM; Pérez-Pinzón, MA; Steinberg, GK; Sun, GH; Yoon, EJ	1
Clark, W; Coull, B; Goldstein, LB; Grotta, J; LaRue, L; Mackay, B; Meissner, I; Murphy, D; Pettigrew, LC	1
Gaspary, HL; Graham, SH; Simon, RP	1
Allegrini, PR; Fagg, GE; Sauer, D	1
Scatton, B	1
Ijaz, S; McCrea, S; Shuaib, A; Wishart, T	1
Ijaz, S; Mazagri, R; Senthilsevlvan, A; Shuaib, A	1
Albers, GW; Davis, SM; Diener, HC; Lees, KR; Norris, J	1
Kometani, M; Nakao, K; Okada, M; Ueda, H	1
Löscher, W; Szabo, L; Wlaź, P	1
Arias, RL; Bowlby, MR; Tasse, JR	1
Gjedde, A; Hakim, AM; Hogan, MJ	1
Hakim, AM; Hogan, M; Takizawa, S	1
Meldrum, BS; Swan, JH	1
Dedman, JR; Earls, RM; Grotta, JC; Picone, CM; Rhoades, HM; Strong, RA; Yao, LP	1

Reviews

2 review(s) available for selfotel and Brain Ischemia

Article	Year
The rise and fall of NMDA antagonists for ischemic stroke. Current molecular medicine, 2004, Volume: 4, Issue:2 Topics: Animals; Brain Ischemia; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Antagonists; Guanidines; Humans; Indoles; Ischemia; N-Methylaspartate; Neurons; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Stroke	2004
Excitatory amino acid receptor antagonists: a novel treatment for ischemic cerebrovascular diseases. Life sciences, 1994, Volume: 55, Issue:25-26 Topics: Animals; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Humans; Pipecolic Acids; Piperidines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate	1994

Trials

2 trial(s) available for selfotel and Brain Ischemia

Article	Year
Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a phase IIa randomized trial. Stroke, 1995, Volume: 26, Issue:4 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Central Nervous System; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate	1995
Termination of Acute Stroke Studies Involving Selfotel Treatment. ASSIST Steering Committed. Lancet (London, England), 1997, Jan-04, Volume: 349, Issue:9044 Topics: Aged; Brain Ischemia; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Pipecolic Acids; Treatment Outcome	1997

Article

Year

Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a phase IIa randomized trial.

Stroke, 1995, Volume: 26, Issue:4

Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Central Nervous System; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate

1995

Termination of Acute Stroke Studies Involving Selfotel Treatment. ASSIST Steering Committed.

Lancet (London, England), 1997, Jan-04, Volume: 349, Issue:9044

Topics: Aged; Brain Ischemia; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Pipecolic Acids; Treatment Outcome

1997

Other Studies

15 other study(ies) available for selfotel and Brain Ischemia

Article	Year
Glutamate receptor antagonists modulate heat shock protein response in focal brain ischemia. Neurological research, 2003, Volume: 25, Issue:2 Topics: Animals; Brain Ischemia; Excitatory Amino Acid Antagonists; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP72 Heat-Shock Proteins; Infarction, Middle Cerebral Artery; Male; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred SHR	2003
Post-ischemic therapy with CGS-19755 (alone or in combination with hypothermia) in gerbils. Neuroscience letters, 1995, May-19, Volume: 191, Issue:1-2 Topics: Animals; Brain Ischemia; Combined Modality Therapy; Gerbillinae; Hypothermia, Induced; Injections, Intraperitoneal; Male; Maze Learning; N-Methylaspartate; Pipecolic Acids; Prosencephalon	1995
In vitro binding of [3H]nimodipine and [3H]CGS-19755 to rat brain in focal cerebral ischemia. Experimental neurology, 1995, Volume: 134, Issue:1 Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Brain Ischemia; Male; N-Methylaspartate; Nimodipine; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Tritium	1995
Correlation of CGS 19755 neuroprotection against in vitro excitotoxicity and focal cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1995, Volume: 15, Issue:5 Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Evoked Potentials, Somatosensory; In Vitro Techniques; Magnetic Resonance Imaging; Male; Mice; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Pipecolic Acids; Rabbits	1995
BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis. European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3 Topics: Analysis of Variance; Animals; Binding, Competitive; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; N-Methylaspartate; Necrosis; Neurons; Observer Variation; Pipecolic Acids; Prosencephalon; Pyrimidines; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion Injury	1994
The competitive NMDA receptor antagonist CGP 40116 is a potent neuroprotectant in a rat model of focal cerebral ischemia. Journal of neural transmission. Supplementum, 1994, Volume: 43 Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Brain Ischemia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Pipecolic Acids; Piperazines; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate	1994
Mortality in gerbils with repetitive ischemia: CGSGS-19755/hypothermia therapy. Neuroscience letters, 1994, Mar-28, Volume: 170, Issue:1 Topics: Animals; Brain Ischemia; Cell Death; Combined Modality Therapy; Gerbillinae; Hypothermia, Induced; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Prosencephalon; Recurrence	1994
CGS-19755 is neuroprotective during repetitive ischemia: this effect is significantly enhanced when combined with hypothermia. Neuroscience, 1993, Volume: 56, Issue:4 Topics: Animals; Brain Ischemia; Cerebral Cortex; Combined Modality Therapy; Gerbillinae; Hippocampus; Hypothermia, Induced; Male; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Recurrence; Severity of Illness Index; Substantia Nigra	1993
Effect of D-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid on focal cerebral ischemia in cat. Arzneimittel-Forschung, 1997, Volume: 47, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Ischemia; Cats; Cerebral Infarction; Excitatory Amino Acid Antagonists; Image Processing, Computer-Assisted; Male; Neuroprotective Agents; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate	1997
Focal ischemia enhances the adverse effect potential of N-methyl-D-aspartate receptor antagonists in rats. Neuroscience letters, 1998, Jan-02, Volume: 240, Issue:1 Topics: Animals; Behavior, Animal; Binding, Competitive; Brain; Brain Ischemia; Cerebrovascular Disorders; Dizocilpine Maleate; Injections, Intraperitoneal; Male; Pipecolic Acids; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1998
Neuroprotective interaction effects of NMDA and AMPA receptor antagonists in an in vitro model of cerebral ischemia. Brain research, 1999, Jan-23, Volume: 816, Issue:2 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hypoxia; Male; Neuroprotective Agents; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	1999
In vivo distribution of CGS-19755 within brain in a model of focal cerebral ischemia. Journal of neurochemistry, 1992, Volume: 58, Issue:1 Topics: Animals; Brain; Brain Ischemia; Electrocoagulation; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Reference Values; Tissue Distribution	1992
The effects of a competitive NMDA receptor antagonist (CGS-19755) on cerebral blood flow and pH in focal ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1991, Volume: 11, Issue:5 Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Hydrogen-Ion Concentration; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
Protection by NMDA antagonists against selective cell loss following transient ischaemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
Neuronal protection correlates with prevention of calcium-calmodulin binding in rats. Stroke, 1990, Volume: 21, Issue:11 Suppl Topics: Animals; Brain Ischemia; Calcium; Calmodulin; Hippocampus; Neurons; Nicardipine; Nimodipine; Pipecolic Acids; Piperidines; Rats	1990