selenocysteine and Neoplasms

selenocysteine has been researched along with Neoplasms in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.63)18.2507
2000's7 (18.42)29.6817
2010's23 (60.53)24.3611
2020's7 (18.42)2.80

Authors

AuthorsStudies
Cao, M; Dai, Y; Pan, S; Sun, C; Tan, Y; Xu, H; Zhang, L1
Arnér, ESJ; Cheng, Q; Gencheva, R1
Seale, LA; Shimada, BK; Swanson, S; Toh, P1
DeAngelo, SL; Győrffy, B; Koutmos, M; Shah, YM1
Kai, X; Li, M; Sheng, Z; Shi, Y; Yin, X; Zhang, L; Zhang, Y1
Carlisle, AE; Doshi, MB; Greer, PL; Joseph, AB; Kim, D; Lee, N; Li, R; Matthew-Onabanjo, AN; Park, SJ; Peppers, A; Shaw, LM; Simin, K; Smith, M; Spears, ME; Youkana, D; Zhu, LJ1
Diamond, AM; Kadkol, S1
Arnér, ESJ; Gencheva, R1
Bergan, R; Burk, RF; Davis, W; George, S; Hill, KE; Marshall, JR; Payne Ondracek, R; Perloff, M; Pili, R1
Chen, C; Du, J; Ge, C; Gu, Z; Liu, J; Wu, R; Yan, L; Yi, X; Yong, Y; Zhang, X; Zhao, Y1
Kai, X; Xue, Y; Yin, X; Zhang, L; Zhang, Y; Zhao, J; Zheng, Y1
Aitken, JB; Finney, L; Harris, HH; Vogt, S; Weekley, CM; Witting, PK1
Chen, Q; Hao, X; Li, J; Liu, H; Liu, J; Liu, L; Ma, B; Mu, C; Yan, C; Yue, W; Zhao, L; Zhu, Y1
Harris, HH; Weekley, CM1
Barbante, C; Jitaru, P; Roman, M1
Carlson, BA; Gladyshev, VN; Hatfield, DL; Tsuji, PA1
Cao, S; Durrani, FA; Rustum, YM; Tóth, K1
Alcutt, S; Artigues, A; Cooper, AJ; Dorai, T; Jones, ME; Krasnikov, BF; Li, J; Pinto, JT; Villar, MT1
Bindoli, A; Citta, A; Folda, A; Jaouen, G; Pigeon, P; Rigobello, MP; Salmain, M; Top, S; Vessières, A1
Begley, TJ; Begley, U; Clark, R; Dedon, PC; Dziergowska, A; Endres, L; Gu, C; Małkiewicz, A; Melendez, JA1
Cheremushkina, IV; Varlamova, EG1
Gangapurkar, B; Jariwalla, RJ; Nakamura, D1
Echigo, S; Endo, M; Rikiishi, H; Shinohara, F; Suzuki, M1
Cheng, WH; Kang, MM; Schoene, NW; Wu, M1
Handy, DE; Loscalzo, J; Lubos, E1
Aitken, JB; de Jonge, MD; Finney, LA; Harris, HH; Howard, DL; Musgrave, IF; Paterson, DJ; Vogt, S; Weekley, CM1
Liu, X; Pietsch, KE; Sturla, SJ1
Bhattacharya, A1
Bernhard, EJ1
Antoch, MP; Chernov, MV; Comas-Soberats, M; Fedtsova, N; Gleiberman, AS; Gudkov, AV; Hu, Y; Jackson, M; Kuropatwinski, KK; Rustum, YM; Spengler, ML1
Burke, TR; Cui, H; Rader, C; Thomas, JD1
Cao, S; Durrani, FA; Rustum, YM1
Cao, S; Durrani, FA; Fakih, M; Rustum, YM1
Rayman, MP1
Abdulah, R; Koyama, H; Miyazaki, K; Nakazawa, M1
Azrak, RG; Cao, S; Combs, GF; Durrani, FA; Fakih, M; Pendyala, L; Prey, J; Rustum, YM; Smith, PF1
Ganther, HE2

Reviews

18 review(s) available for selenocysteine and Neoplasms

ArticleYear
Thioredoxin reductase selenoproteins from different organisms as potential drug targets for treatment of human diseases.
    Free radical biology & medicine, 2022, Volume: 190

    Topics: Humans; Neoplasms; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Tumor Microenvironment

2022
Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers.
    Biomolecules, 2022, 10-28, Volume: 12, Issue:11

    Topics: Ferroptosis; Humans; Neoplasms; Selenium; Selenocysteine; Selenoproteins

2022
Selenoproteins and tRNA-Sec: regulators of cancer redox homeostasis.
    Trends in cancer, 2023, Volume: 9, Issue:12

    Topics: Antioxidants; Homeostasis; Humans; Neoplasms; Oxidation-Reduction; RNA, Transfer; Selenium; Selenocysteine; Selenoproteins

2023
The Interaction between Dietary Selenium Intake and Genetics in Determining Cancer Risk and Outcome.
    Nutrients, 2020, Aug-12, Volume: 12, Issue:8

    Topics: 3' Untranslated Regions; Codon, Terminator; Eating; Genetic Predisposition to Disease; Humans; Neoplasms; Nutrigenomics; Protein Biosynthesis; Risk Factors; RNA, Messenger; Selenium; Selenocysteine; Selenoproteins

2020
Thioredoxin Reductase Inhibition for Cancer Therapy.
    Annual review of pharmacology and toxicology, 2022, 01-06, Volume: 62

    Topics: Animals; Humans; Mice; Mitochondria; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Selenocysteine; Thioredoxin Reductase 1

2022
Selenium metabolism in cancer cells: the combined application of XAS and XFM techniques to the problem of selenium speciation in biological systems.
    Nutrients, 2013, May-21, Volume: 5, Issue:5

    Topics: Animals; Copper; Fluorescence; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenomethionine; Sodium Selenite; X-Ray Absorption Spectroscopy

2013
Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease.
    Chemical Society reviews, 2013, Dec-07, Volume: 42, Issue:23

    Topics: Clinical Trials as Topic; Cystine; Dietary Supplements; Histone Deacetylase Inhibitors; Humans; Neoplasms; Organoselenium Compounds; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins; Sulfhydryl Compounds

2013
Selenium biochemistry and its role for human health.
    Metallomics : integrated biometal science, 2014, Volume: 6, Issue:1

    Topics: Diabetes Mellitus; Humans; Inflammation; Metabolic Networks and Pathways; Models, Biological; Neoplasms; Selenium; Selenocysteine; Selenoproteins; Trace Elements

2014
Selenium and selenocysteine: roles in cancer, health, and development.
    Trends in biochemical sciences, 2014, Volume: 39, Issue:3

    Topics: Humans; Neoplasm Proteins; Neoplasms; Selenium; Selenocysteine; Selenoproteins

2014
Contribution of mammalian selenocysteine-containing proteins to carcinogenesis.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2017, Volume: 39

    Topics: Animals; Carcinogenesis; Humans; Neoplasms; Selenium; Selenocysteine; Selenoproteins

2017
Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities.
    Antioxidants & redox signaling, 2011, Oct-01, Volume: 15, Issue:7

    Topics: Amino Acid Sequence; Animals; Cardiovascular Diseases; Cell Death; Diabetes Mellitus; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Genetic Predisposition to Disease; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Molecular Sequence Data; Neoplasms; Oxidation-Reduction; Oxidative Stress; Polymorphism, Genetic; Protein Conformation; Reactive Oxygen Species; Risk Factors; Selenocysteine

2011
Methylselenocysteine: a promising antiangiogenic agent for overcoming drug delivery barriers in solid malignancies for therapeutic synergy with anticancer drugs.
    Expert opinion on drug delivery, 2011, Volume: 8, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cysteine; Drug Synergism; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine

2011
Interventions that induce modifications in the tumor microenvironment.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Adhesion; Cell Hypoxia; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cysteine; Cytotoxins; Drug Screening Assays, Antitumor; Extracellular Matrix; Genetic Therapy; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Neoplastic Stem Cells; Neovascularization, Pathologic; Organoselenium Compounds; Radiation Tolerance; Radiotherapy; Selenocysteine; Signal Transduction; Stromal Cells; Tumor Microenvironment

2011
Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cysteine; Drug Synergism; Humans; Irinotecan; Mice; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Selenomethionine

2005
Selenium in cancer prevention: a review of the evidence and mechanism of action.
    The Proceedings of the Nutrition Society, 2005, Volume: 64, Issue:4

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Gene Expression Regulation, Neoplastic; Genotype; Humans; Neoplasms; Oxidation-Reduction; Selenium; Selenocysteine; Selenoproteins

2005
Chemical forms of selenium for cancer prevention.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2005, Volume: 19, Issue:2-3

    Topics: Anticarcinogenic Agents; Chromatography; Chromatography, High Pressure Liquid; Cysteine; Food; Glutathione Peroxidase; Humans; Iodide Peroxidase; Mass Spectrometry; Methionine Sulfoxide Reductases; Models, Chemical; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenoprotein P; Selenoprotein W; Thioredoxin-Disulfide Reductase

2005
Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle Proteins; Cell Division; Cysteine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Methylation; Mice; Molecular Weight; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction; Protein Kinase C; Proteins; Selenium; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Thioredoxins; Transcription Factors

1999
Selenium metabolism and mechanisms of cancer prevention.
    Advances in experimental medicine and biology, 2001, Volume: 492

    Topics: Anticarcinogenic Agents; Antioxidants; Humans; Neoplasms; Nutritional Requirements; Proteins; Selenium; Selenocysteine; Selenoproteins

2001

Trials

1 trial(s) available for selenocysteine and Neoplasms

ArticleYear
Selenomethionine and methyl selenocysteine: multiple-dose pharmacokinetics in selenium-replete men.
    Oncotarget, 2017, Apr-18, Volume: 8, Issue:16

    Topics: Adult; Aged; Case-Control Studies; Chemoprevention; Dietary Supplements; Drug Monitoring; Humans; Male; Middle Aged; Neoplasms; Selenocysteine; Selenomethionine; Time Factors

2017

Other Studies

19 other study(ies) available for selenocysteine and Neoplasms

ArticleYear
Copper-Selenocysteine Quantum Dots for NIR-II Photothermally Enhanced Chemodynamic Therapy.
    ACS applied bio materials, 2022, 04-18, Volume: 5, Issue:4

    Topics: Catalysis; Copper; Humans; Nanoparticles; Neoplasms; Quantum Dots; Selenocysteine

2022
Bioluminescence Imaging of Selenocysteine in Vivo with a Highly Sensitive Probe.
    ACS sensors, 2019, 12-27, Volume: 4, Issue:12

    Topics: Animals; Benzothiazoles; Female; Humans; Limit of Detection; Luminescence; Luminescent Agents; Luminescent Measurements; MCF-7 Cells; Mice, Inbred BALB C; Mice, Transgenic; Neoplasms; Optical Imaging; Selenocysteine

2019
Selenium detoxification is required for cancer-cell survival.
    Nature metabolism, 2020, Volume: 2, Issue:7

    Topics: Amino Acid Transport System y+; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Ferroptosis; Humans; Inactivation, Metabolic; Mice; Mice, Nude; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase; Phosphotransferases; Selenium; Selenium Compounds; Selenocysteine; Xenograft Model Antitumor Assays

2020
Poly(Vinylpyrollidone)- and Selenocysteine-Modified Bi
    Advanced materials (Deerfield Beach, Fla.), 2017, Volume: 29, Issue:34

    Topics: Bismuth; Humans; Nanoparticles; Neoplasms; Organoselenium Compounds; Polyvinyls; Pyrrolidinones; Radiation-Sensitizing Agents; Selenium Compounds; Selenocysteine; Theranostic Nanomedicine

2017
A reaction-based near-infrared fluorescent probe that can visualize endogenous selenocysteine in vivo in tumor-bearing mice.
    The Analyst, 2018, Oct-08, Volume: 143, Issue:20

    Topics: Animals; Drug Stability; Female; Fluorescence; Fluorescent Dyes; Heterografts; Humans; Limit of Detection; Male; MCF-7 Cells; Mice, Nude; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasm Transplantation; Neoplasms; Nitriles; Optical Imaging; Selenocysteine; Ultraviolet Rays

2018
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis.
    Free radical biology & medicine, 2013, Volume: 63

    Topics: Animals; Antineoplastic Agents; Apoptosis; Catalytic Domain; Diterpenes; Fibroblasts; HCT116 Cells; Humans; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Selenocysteine; Selenoproteins; Thioredoxin Reductase 1; Thioredoxin Reductase 2; Thioredoxin-Disulfide Reductase; Thioredoxins

2013
Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models.
    British journal of cancer, 2014, Apr-02, Volume: 110, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Cyclophosphamide; Cytoprotection; Female; Humans; Irinotecan; Mice; Mice, Nude; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Rats; Rats, Inbred F344; Selenocysteine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2014
Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionine.
    The Journal of biological chemistry, 2014, Nov-07, Volume: 289, Issue:45

    Topics: Alkenes; Animals; Carbon-Sulfur Lyases; Cysteine; Histone Deacetylase Inhibitors; Humans; Kinetics; Liver; Mice; Neoplasms; Recombinant Proteins; Selenocysteine; Selenomethionine; Substrate Specificity; Tandem Mass Spectrometry; Transaminases

2014
Evidence for targeting thioredoxin reductases with ferrocenyl quinone methides. A possible molecular basis for the antiproliferative effect of hydroxyferrocifens on cancer cells.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Animals; Antineoplastic Agents; Cystamine; Ferrous Compounds; Glutathione; Glutathione Reductase; Humans; Indolequinones; Inhibitory Concentration 50; Jurkat Cells; Metallocenes; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Thioredoxin-Disulfide Reductase

2014
Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: AlkB Homolog 8, tRNA Methyltransferase; Animals; DNA Damage; Fibroblasts; Gene Expression; Gene Expression Regulation; Glutathione Peroxidase; Mice; Mice, Inbred C57BL; Neoplasms; Oxidative Stress; Protein Processing, Post-Translational; Reactive Oxygen Species; RNA, Transfer; Selenocysteine; Thioredoxin-Disulfide Reductase; tRNA Methyltransferases; Uridine

2015
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
    The British journal of nutrition, 2009, Volume: 101, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms

2009
Differential apoptotic response of human cancer cells to organoselenium compounds.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Flow Cytometry; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Tumor Suppressor Protein p53

2010
Selenium compounds activate early barriers of tumorigenesis.
    The Journal of biological chemistry, 2010, Apr-16, Volume: 285, Issue:16

    Topics: Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cellular Senescence; Cysteine; DNA Damage; DNA Repair; DNA-Binding Proteins; Histones; Humans; Male; Neoplasms; Organoselenium Compounds; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins

2010
Uptake, distribution, and speciation of selenoamino acids by human cancer cells: X-ray absorption and fluorescence methods.
    Biochemistry, 2011, Mar-15, Volume: 50, Issue:10

    Topics: Cell Line, Tumor; Cysteine; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; X-Ray Absorption Spectroscopy

2011
Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes.
    Chemical research in toxicology, 2011, May-16, Volume: 24, Issue:5

    Topics: Agaricales; Alkylation; Antineoplastic Agents; Antioxidants; Cell Survival; Cysteine; Enzyme Inhibitors; Glutathione Peroxidase; HeLa Cells; Humans; Neoplasms; Polycyclic Sesquiterpenes; Selenocysteine; Sesquiterpenes; Spiro Compounds; Thioredoxin-Disulfide Reductase

2011
Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1.
    Oncotarget, 2011, Volume: 2, Issue:12

    Topics: Animals; ARNTL Transcription Factors; Cell Line, Tumor; Circadian Clocks; CLOCK Proteins; Cyclophosphamide; Cysteine; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neoplasms; Organoselenium Compounds; Period Circadian Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Selenium Compounds; Selenocysteine; Transcription Factors; Transcription, Genetic; Transcriptional Activation

2011
Chemically programmed bispecific antibodies that recruit and activate T cells.
    The Journal of biological chemistry, 2012, Aug-17, Volume: 287, Issue:34

    Topics: Antibodies, Bispecific; Antibody Specificity; CD3 Complex; Folate Receptor 1; HeLa Cells; Humans; Integrin alpha4beta1; Jurkat Cells; Lymphocyte Activation; Neoplasms; Selenocysteine; T-Lymphocytes

2012
Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoselenium Compounds; Radiation-Sensitizing Agents; Selenium; Selenocysteine; Selenomethionine; Time Factors

2004
Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.
    Biochemical pharmacology, 2007, May-01, Volume: 73, Issue:9

    Topics: Administration, Oral; Animals; Bone Marrow; Camptothecin; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Irinotecan; Kidney; Kinetics; Liver; Mice; Mice, Nude; Neoplasms; Organoselenium Compounds; Plasma; Selenium; Selenocysteine

2007