selenocysteine and Benign Neoplasms

selenocysteine has been researched along with Benign Neoplasms in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.63)18.2507
2000's7 (18.42)29.6817
2010's23 (60.53)24.3611
2020's7 (18.42)2.80

Authors

AuthorsStudies
Cao, M; Dai, Y; Pan, S; Sun, C; Tan, Y; Xu, H; Zhang, L1
Arnér, ESJ; Cheng, Q; Gencheva, R1
Seale, LA; Shimada, BK; Swanson, S; Toh, P1
DeAngelo, SL; Győrffy, B; Koutmos, M; Shah, YM1
Kai, X; Li, M; Sheng, Z; Shi, Y; Yin, X; Zhang, L; Zhang, Y1
Carlisle, AE; Doshi, MB; Greer, PL; Joseph, AB; Kim, D; Lee, N; Li, R; Matthew-Onabanjo, AN; Park, SJ; Peppers, A; Shaw, LM; Simin, K; Smith, M; Spears, ME; Youkana, D; Zhu, LJ1
Diamond, AM; Kadkol, S1
Arnér, ESJ; Gencheva, R1
Bergan, R; Burk, RF; Davis, W; George, S; Hill, KE; Marshall, JR; Payne Ondracek, R; Perloff, M; Pili, R1
Chen, C; Du, J; Ge, C; Gu, Z; Liu, J; Wu, R; Yan, L; Yi, X; Yong, Y; Zhang, X; Zhao, Y1
Kai, X; Xue, Y; Yin, X; Zhang, L; Zhang, Y; Zhao, J; Zheng, Y1
Aitken, JB; Finney, L; Harris, HH; Vogt, S; Weekley, CM; Witting, PK1
Chen, Q; Hao, X; Li, J; Liu, H; Liu, J; Liu, L; Ma, B; Mu, C; Yan, C; Yue, W; Zhao, L; Zhu, Y1
Harris, HH; Weekley, CM1
Barbante, C; Jitaru, P; Roman, M1
Carlson, BA; Gladyshev, VN; Hatfield, DL; Tsuji, PA1
Cao, S; Durrani, FA; Rustum, YM; Tóth, K1
Alcutt, S; Artigues, A; Cooper, AJ; Dorai, T; Jones, ME; Krasnikov, BF; Li, J; Pinto, JT; Villar, MT1
Bindoli, A; Citta, A; Folda, A; Jaouen, G; Pigeon, P; Rigobello, MP; Salmain, M; Top, S; Vessières, A1
Begley, TJ; Begley, U; Clark, R; Dedon, PC; Dziergowska, A; Endres, L; Gu, C; Małkiewicz, A; Melendez, JA1
Cheremushkina, IV; Varlamova, EG1
Gangapurkar, B; Jariwalla, RJ; Nakamura, D1
Echigo, S; Endo, M; Rikiishi, H; Shinohara, F; Suzuki, M1
Cheng, WH; Kang, MM; Schoene, NW; Wu, M1
Handy, DE; Loscalzo, J; Lubos, E1
Aitken, JB; de Jonge, MD; Finney, LA; Harris, HH; Howard, DL; Musgrave, IF; Paterson, DJ; Vogt, S; Weekley, CM1
Liu, X; Pietsch, KE; Sturla, SJ1
Bhattacharya, A1
Bernhard, EJ1
Antoch, MP; Chernov, MV; Comas-Soberats, M; Fedtsova, N; Gleiberman, AS; Gudkov, AV; Hu, Y; Jackson, M; Kuropatwinski, KK; Rustum, YM; Spengler, ML1
Burke, TR; Cui, H; Rader, C; Thomas, JD1
Cao, S; Durrani, FA; Rustum, YM1
Cao, S; Durrani, FA; Fakih, M; Rustum, YM1
Rayman, MP1
Abdulah, R; Koyama, H; Miyazaki, K; Nakazawa, M1
Azrak, RG; Cao, S; Combs, GF; Durrani, FA; Fakih, M; Pendyala, L; Prey, J; Rustum, YM; Smith, PF1
Ganther, HE2

Reviews

18 review(s) available for selenocysteine and Benign Neoplasms

ArticleYear
Thioredoxin reductase selenoproteins from different organisms as potential drug targets for treatment of human diseases.
    Free radical biology & medicine, 2022, Volume: 190

    Topics: Humans; Neoplasms; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Tumor Microenvironment

2022
Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers.
    Biomolecules, 2022, 10-28, Volume: 12, Issue:11

    Topics: Ferroptosis; Humans; Neoplasms; Selenium; Selenocysteine; Selenoproteins

2022
Selenoproteins and tRNA-Sec: regulators of cancer redox homeostasis.
    Trends in cancer, 2023, Volume: 9, Issue:12

    Topics: Antioxidants; Homeostasis; Humans; Neoplasms; Oxidation-Reduction; RNA, Transfer; Selenium; Selenocysteine; Selenoproteins

2023
The Interaction between Dietary Selenium Intake and Genetics in Determining Cancer Risk and Outcome.
    Nutrients, 2020, Aug-12, Volume: 12, Issue:8

    Topics: 3' Untranslated Regions; Codon, Terminator; Eating; Genetic Predisposition to Disease; Humans; Neoplasms; Nutrigenomics; Protein Biosynthesis; Risk Factors; RNA, Messenger; Selenium; Selenocysteine; Selenoproteins

2020
Thioredoxin Reductase Inhibition for Cancer Therapy.
    Annual review of pharmacology and toxicology, 2022, 01-06, Volume: 62

    Topics: Animals; Humans; Mice; Mitochondria; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Selenocysteine; Thioredoxin Reductase 1

2022
Selenium metabolism in cancer cells: the combined application of XAS and XFM techniques to the problem of selenium speciation in biological systems.
    Nutrients, 2013, May-21, Volume: 5, Issue:5

    Topics: Animals; Copper; Fluorescence; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenomethionine; Sodium Selenite; X-Ray Absorption Spectroscopy

2013
Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease.
    Chemical Society reviews, 2013, Dec-07, Volume: 42, Issue:23

    Topics: Clinical Trials as Topic; Cystine; Dietary Supplements; Histone Deacetylase Inhibitors; Humans; Neoplasms; Organoselenium Compounds; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins; Sulfhydryl Compounds

2013
Selenium biochemistry and its role for human health.
    Metallomics : integrated biometal science, 2014, Volume: 6, Issue:1

    Topics: Diabetes Mellitus; Humans; Inflammation; Metabolic Networks and Pathways; Models, Biological; Neoplasms; Selenium; Selenocysteine; Selenoproteins; Trace Elements

2014
Selenium and selenocysteine: roles in cancer, health, and development.
    Trends in biochemical sciences, 2014, Volume: 39, Issue:3

    Topics: Humans; Neoplasm Proteins; Neoplasms; Selenium; Selenocysteine; Selenoproteins

2014
Contribution of mammalian selenocysteine-containing proteins to carcinogenesis.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2017, Volume: 39

    Topics: Animals; Carcinogenesis; Humans; Neoplasms; Selenium; Selenocysteine; Selenoproteins

2017
Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities.
    Antioxidants & redox signaling, 2011, Oct-01, Volume: 15, Issue:7

    Topics: Amino Acid Sequence; Animals; Cardiovascular Diseases; Cell Death; Diabetes Mellitus; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Genetic Predisposition to Disease; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Molecular Sequence Data; Neoplasms; Oxidation-Reduction; Oxidative Stress; Polymorphism, Genetic; Protein Conformation; Reactive Oxygen Species; Risk Factors; Selenocysteine

2011
Methylselenocysteine: a promising antiangiogenic agent for overcoming drug delivery barriers in solid malignancies for therapeutic synergy with anticancer drugs.
    Expert opinion on drug delivery, 2011, Volume: 8, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cysteine; Drug Synergism; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine

2011
Interventions that induce modifications in the tumor microenvironment.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Adhesion; Cell Hypoxia; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cysteine; Cytotoxins; Drug Screening Assays, Antitumor; Extracellular Matrix; Genetic Therapy; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Neoplastic Stem Cells; Neovascularization, Pathologic; Organoselenium Compounds; Radiation Tolerance; Radiotherapy; Selenocysteine; Signal Transduction; Stromal Cells; Tumor Microenvironment

2011
Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cysteine; Drug Synergism; Humans; Irinotecan; Mice; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Selenomethionine

2005
Selenium in cancer prevention: a review of the evidence and mechanism of action.
    The Proceedings of the Nutrition Society, 2005, Volume: 64, Issue:4

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Gene Expression Regulation, Neoplastic; Genotype; Humans; Neoplasms; Oxidation-Reduction; Selenium; Selenocysteine; Selenoproteins

2005
Chemical forms of selenium for cancer prevention.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2005, Volume: 19, Issue:2-3

    Topics: Anticarcinogenic Agents; Chromatography; Chromatography, High Pressure Liquid; Cysteine; Food; Glutathione Peroxidase; Humans; Iodide Peroxidase; Mass Spectrometry; Methionine Sulfoxide Reductases; Models, Chemical; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenoprotein P; Selenoprotein W; Thioredoxin-Disulfide Reductase

2005
Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle Proteins; Cell Division; Cysteine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Methylation; Mice; Molecular Weight; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction; Protein Kinase C; Proteins; Selenium; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Thioredoxins; Transcription Factors

1999
Selenium metabolism and mechanisms of cancer prevention.
    Advances in experimental medicine and biology, 2001, Volume: 492

    Topics: Anticarcinogenic Agents; Antioxidants; Humans; Neoplasms; Nutritional Requirements; Proteins; Selenium; Selenocysteine; Selenoproteins

2001

Trials

1 trial(s) available for selenocysteine and Benign Neoplasms

ArticleYear
Selenomethionine and methyl selenocysteine: multiple-dose pharmacokinetics in selenium-replete men.
    Oncotarget, 2017, Apr-18, Volume: 8, Issue:16

    Topics: Adult; Aged; Case-Control Studies; Chemoprevention; Dietary Supplements; Drug Monitoring; Humans; Male; Middle Aged; Neoplasms; Selenocysteine; Selenomethionine; Time Factors

2017

Other Studies

19 other study(ies) available for selenocysteine and Benign Neoplasms

ArticleYear
Copper-Selenocysteine Quantum Dots for NIR-II Photothermally Enhanced Chemodynamic Therapy.
    ACS applied bio materials, 2022, 04-18, Volume: 5, Issue:4

    Topics: Catalysis; Copper; Humans; Nanoparticles; Neoplasms; Quantum Dots; Selenocysteine

2022
Bioluminescence Imaging of Selenocysteine in Vivo with a Highly Sensitive Probe.
    ACS sensors, 2019, 12-27, Volume: 4, Issue:12

    Topics: Animals; Benzothiazoles; Female; Humans; Limit of Detection; Luminescence; Luminescent Agents; Luminescent Measurements; MCF-7 Cells; Mice, Inbred BALB C; Mice, Transgenic; Neoplasms; Optical Imaging; Selenocysteine

2019
Selenium detoxification is required for cancer-cell survival.
    Nature metabolism, 2020, Volume: 2, Issue:7

    Topics: Amino Acid Transport System y+; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Ferroptosis; Humans; Inactivation, Metabolic; Mice; Mice, Nude; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase; Phosphotransferases; Selenium; Selenium Compounds; Selenocysteine; Xenograft Model Antitumor Assays

2020
Poly(Vinylpyrollidone)- and Selenocysteine-Modified Bi
    Advanced materials (Deerfield Beach, Fla.), 2017, Volume: 29, Issue:34

    Topics: Bismuth; Humans; Nanoparticles; Neoplasms; Organoselenium Compounds; Polyvinyls; Pyrrolidinones; Radiation-Sensitizing Agents; Selenium Compounds; Selenocysteine; Theranostic Nanomedicine

2017
A reaction-based near-infrared fluorescent probe that can visualize endogenous selenocysteine in vivo in tumor-bearing mice.
    The Analyst, 2018, Oct-08, Volume: 143, Issue:20

    Topics: Animals; Drug Stability; Female; Fluorescence; Fluorescent Dyes; Heterografts; Humans; Limit of Detection; Male; MCF-7 Cells; Mice, Nude; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasm Transplantation; Neoplasms; Nitriles; Optical Imaging; Selenocysteine; Ultraviolet Rays

2018
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis.
    Free radical biology & medicine, 2013, Volume: 63

    Topics: Animals; Antineoplastic Agents; Apoptosis; Catalytic Domain; Diterpenes; Fibroblasts; HCT116 Cells; Humans; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Selenocysteine; Selenoproteins; Thioredoxin Reductase 1; Thioredoxin Reductase 2; Thioredoxin-Disulfide Reductase; Thioredoxins

2013
Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models.
    British journal of cancer, 2014, Apr-02, Volume: 110, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Cyclophosphamide; Cytoprotection; Female; Humans; Irinotecan; Mice; Mice, Nude; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Rats; Rats, Inbred F344; Selenocysteine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2014
Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionine.
    The Journal of biological chemistry, 2014, Nov-07, Volume: 289, Issue:45

    Topics: Alkenes; Animals; Carbon-Sulfur Lyases; Cysteine; Histone Deacetylase Inhibitors; Humans; Kinetics; Liver; Mice; Neoplasms; Recombinant Proteins; Selenocysteine; Selenomethionine; Substrate Specificity; Tandem Mass Spectrometry; Transaminases

2014
Evidence for targeting thioredoxin reductases with ferrocenyl quinone methides. A possible molecular basis for the antiproliferative effect of hydroxyferrocifens on cancer cells.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Animals; Antineoplastic Agents; Cystamine; Ferrous Compounds; Glutathione; Glutathione Reductase; Humans; Indolequinones; Inhibitory Concentration 50; Jurkat Cells; Metallocenes; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Thioredoxin-Disulfide Reductase

2014
Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: AlkB Homolog 8, tRNA Methyltransferase; Animals; DNA Damage; Fibroblasts; Gene Expression; Gene Expression Regulation; Glutathione Peroxidase; Mice; Mice, Inbred C57BL; Neoplasms; Oxidative Stress; Protein Processing, Post-Translational; Reactive Oxygen Species; RNA, Transfer; Selenocysteine; Thioredoxin-Disulfide Reductase; tRNA Methyltransferases; Uridine

2015
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
    The British journal of nutrition, 2009, Volume: 101, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms

2009
Differential apoptotic response of human cancer cells to organoselenium compounds.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Flow Cytometry; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Tumor Suppressor Protein p53

2010
Selenium compounds activate early barriers of tumorigenesis.
    The Journal of biological chemistry, 2010, Apr-16, Volume: 285, Issue:16

    Topics: Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cellular Senescence; Cysteine; DNA Damage; DNA Repair; DNA-Binding Proteins; Histones; Humans; Male; Neoplasms; Organoselenium Compounds; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins

2010
Uptake, distribution, and speciation of selenoamino acids by human cancer cells: X-ray absorption and fluorescence methods.
    Biochemistry, 2011, Mar-15, Volume: 50, Issue:10

    Topics: Cell Line, Tumor; Cysteine; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; X-Ray Absorption Spectroscopy

2011
Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes.
    Chemical research in toxicology, 2011, May-16, Volume: 24, Issue:5

    Topics: Agaricales; Alkylation; Antineoplastic Agents; Antioxidants; Cell Survival; Cysteine; Enzyme Inhibitors; Glutathione Peroxidase; HeLa Cells; Humans; Neoplasms; Polycyclic Sesquiterpenes; Selenocysteine; Sesquiterpenes; Spiro Compounds; Thioredoxin-Disulfide Reductase

2011
Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1.
    Oncotarget, 2011, Volume: 2, Issue:12

    Topics: Animals; ARNTL Transcription Factors; Cell Line, Tumor; Circadian Clocks; CLOCK Proteins; Cyclophosphamide; Cysteine; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neoplasms; Organoselenium Compounds; Period Circadian Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Selenium Compounds; Selenocysteine; Transcription Factors; Transcription, Genetic; Transcriptional Activation

2011
Chemically programmed bispecific antibodies that recruit and activate T cells.
    The Journal of biological chemistry, 2012, Aug-17, Volume: 287, Issue:34

    Topics: Antibodies, Bispecific; Antibody Specificity; CD3 Complex; Folate Receptor 1; HeLa Cells; Humans; Integrin alpha4beta1; Jurkat Cells; Lymphocyte Activation; Neoplasms; Selenocysteine; T-Lymphocytes

2012
Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoselenium Compounds; Radiation-Sensitizing Agents; Selenium; Selenocysteine; Selenomethionine; Time Factors

2004
Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.
    Biochemical pharmacology, 2007, May-01, Volume: 73, Issue:9

    Topics: Administration, Oral; Animals; Bone Marrow; Camptothecin; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Irinotecan; Kidney; Kinetics; Liver; Mice; Mice, Nude; Neoplasms; Organoselenium Compounds; Plasma; Selenium; Selenocysteine

2007