Page last updated: 2024-08-26

selenium and Kashin-Beck Disease

selenium has been researched along with Kashin-Beck Disease in 79 studies

Research

Studies (79)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	52 (65.82)	24.3611
2020's	27 (34.18)	2.80

Authors

Authors	Studies
Chen, X; Du, X; Fu, G; Liu, Q; Qi, M; Shi, C; Sun, N; Xia, Z; Zhang, R	1
Li, B; Luo, K; Zhang, S	1
Bao, M; Deng, H; Han, J; Lin, X; Liu, H; Qu, C; Yang, Z	1
Li, Q; Wang, C; Xiong, Y; Zhang, D; Zhang, R	1
Guo, X; Meng, P; Tan, S; Wang, X; Wu, C; Yuan, L; Zhang, F; Zhang, P	1
Tian, Y; Xiao, J; Yu, C; Zha, X	1
Chen, F; Chen, S; Gong, Y; Guo, X; Hu, M; Huang, R; Kang, L; Liu, Y; Ning, Y; Pei, L; Wang, X; Yang, X; Zhang, F; Zhang, Q; Zhang, Y	1
Li, Q; Xiong, Y; Yang, X; Zhang, D; Zhang, R	1
Ba, Y; Ding, LM; Feng, ZC; Li, ZY; Sun, L; Yang, S; Yu, FF; Yu, SY; Zhou, GY; Zuo, J	1
An, J; Gao, X; Tian, Y; Zha, X	1
Chen, Z; Dun, X; Lu, Y; Wang, H; Wang, X	1
Chu, X; Shi, P; Shi, S; Wang, B; Wen, Y; Yao, Y; Zhang, F; Zhang, L	1
Cao, J; Chen, J; Fang, Q; He, Y; Lammi, MJ; Wang, M; Xue, S; Zhang, M; Zhang, Y	1
Guo, X; Ping, ZG; Qi, X; Shang, YN; Yu, FF	1
Chen, J; Fang, Q; Feng, Y; Li, Z; Liao, Y; Liu, Y; Wang, H; Wang, M; Wang, W; Zhang, M; Zhang, Y	1
Cheng, B; Cheng, S; Du, Y; Goldring, MB; Guo, X; Han, J; Hao, J; Li, P; Liang, C; Liang, X; Liu, L; Ma, M; Ning, Y; Poulet, B; Qi, X; Wang, S; Wang, W; Wang, X; Wen, Y; Wu, C; Xu, P; Zhang, F; Zhang, L; Zhao, G; Zhao, H	1
Chen, J; Guo, X; He, Y; Lin, J; Shi, M; Wang, W; Zhang, Y	1
Li, Z; Shang, L; Sun, G; Wu, Y; Yang, C; Yang, W; Yao, H	1
Gong, H; Li, H; Nima, C; Wang, J; Yang, L; Zhao, S	1
Amhare, AF; Chilufya, MM; Deng, H; Han, J; Lei, J; Liu, J; Lv, Y; Qiao, L; Wang, L; Zhao, Y	1
Kong, C; Li, H; Li, Y; Wang, J; Wang, X; Yang, L	1
Aaron, N; Chen, J; Fan, L; Fang, Q; Feng, Y; He, Y; Ma, T; Sun, J; Wang, H; Zhang, D; Zhang, Y	1
Li, H; Men, Z; Wang, X; Yang, L; Yu, J	1
Chen, J; Li, Z; Liu, Y; Ma, T; Shi, Y; Wang, H; Wang, W; Yi, C; Zhang, M	1
Geng, L; Guo, X; Meng, P; Wang, S; Yuan, L; Zhao, G	1
Li, Q; Li, Z; Wang, C; Xiong, Y; Yang, X; Zhang, D; Zhang, R	1
Chen, C; Chen, JH; Deng, XH; Fang, Q; Li, SY; Wang, WJ; Wang, ZL; Xue, SH; Yang, HJ; Zhang, M; Zhang, Y; Zhou, XR	1
Guo, X; Lammi, M; Lei, Y; Ning, Y; Qu, P; Wang, S; Wang, X; Zhang, F; Zhang, P	1
Chen, F; Ding, D; Geng, D; Guo, X; Lammi, MJ; Liu, H; Shao, W; Tan, X; Yu, F; Yu, Z	1
Du, B; Zhou, J	1
Anatoly, SV; Guo, X; Lammi, M; Li, C; Ning, Y; Prakash, NT; Wang, X; Zhang, F; Zhang, P; Zhou, R	1
Chen, L; Deng, C; Liao, Y; Wang, Y; Xie, D; Yue, J; Zhang, C	1
Chen, JH; He, Y; Jiang, ZC; Wang, MY; Wu, F; Zhang, D; Zhang, M; Zhang, Y	1
Cao, J; Guo, H; Jiang, Y; Li, Y; Liu, J; Mo, X; Sun, W; Wu, R; Xiong, Y; Yang, X; Zhang, R	1
Guo, X; Lammi, MJ; Liu, H; Shao, W; Wang, S; Wang, W; Wu, C; Zhao, G	1
Cao, J; Han, L; Li, B; Li, Z; Liu, J; Ren, H; Shi, Z; Sun, W; Xiong, Y; Yang, X; Zhang, D; Zhang, J; Zhang, R	1
Guo, X; Li, X; Wang, X; Xu, C; Yang, L; Zhang, J	1
Guo, D; Guo, Y; Han, Y; Huang, H; Hussain, S; Lu, S; Min, Z; Sun, J; Sun, M; Xu, P; Zhang, F; Zhao, W; Zhao, Y; Zhong, N	1
Cao, Y; Cui, S; Deng, Q; Liu, H; Sun, L; Wang, S; Yu, J	1
Guo, X; Guo, Y; Han, J; Qu, C; Wang, L; Yan, S; Zhou, Y	1
Guo, X; Li, C; Ning, Y; Wang, X; Zhang, P; Zhou, R	1
Guo, X; Han, J; Lei, J; Qu, C; Wang, L; Yang, B; Yin, J	1
Dong, B; Hu, J; Su, J; Zhang, W; Zhou, Q; Zou, K	1
Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z	1
Cao, J; Chen, J; Goldring, MB; Luo, M; Wang, W; Wang, Z; Wei, S; Yang, Z; Yu, B	1
Chen, C; Chen, J; Li, S; Song, D; Wang, W; Wang, Z; Xue, S; Yang, H; Zhou, X	1
Cheng, J; Gong, B; Huang, L; Lin, H; Lin, Y; Liu, X; Lu, F; Ma, S; Shi, Y; Yang, J; Yang, Z; Zheng, H	1
Chen, Z; Feng, F; Li, H; Li, Y; Wang, J; Yang, L; Yu, J	1
Bai, YD; Dennis, BS; Guo, X; Qu, CJ; Wang, WZ; Wu, CY; Wu, SX; Zhang, F	1
Dennis, BS; Guo, X; Han, J; Lei, Y; Wu, C; Wu, S	1
Lv, Y; Wang, Q; Yang, Z; Yu, T; Zhang, M; Zhao, W	1
He, CZ; Li, Q; Man, WW; Meng, FG; Sa, RL; Sun, LY; Wang, LH; Wang, SP; Zhao, ZJ	1
Bai, Y; Guo, X; Liu, J; Pang, Q; Wang, L; Wu, C; Wu, S; Xu, P	1
Chen, Z; Danzeng, S; Deji, Y; Gong, H; Guo, M; Li, H; Li, Y; Nima, C; Wang, J; Wang, W; Yang, L; Ye, B; Zhao, S	1
Du, R; Li, Q; Liu, YF; Ma, X; Xu, XQ; Yang, PZ; Yu, HZ; Zhao, ZJ; Zhu, L	1
Chen, J; Guan, F; Song, D; Wang, Z; Xue, S; Yang, H; Zhou, X	1
Duan, C; Guo, X; Wang, S; Wang, X; Zhang, F	1
Fang, H; Guo, X; Han, J; Liu, H; Wang, X; Yu, FF	1
Guo, X; Lei, Y; Ning, Y; Wang, S; Wang, X; Zhang, F; Zhang, L	1
Guo, X; Yang, L; Yu, FF; Zhang, RQ; Zhao, GH	1
Dennis, BS; Guo, X; He, S; Hu, S; Jiang, N; Lei, R; Zhang, Q	1
Cao, J; Dai, X; Kou, Y; Li, Y; Mo, X; Xiong, Y; Zhang, R	1
Lei, XG; Prabhu, KS	1
Duan, C; Guo, X; Han, J; Liu, H; Shao, W; Wang, S; Wu, C	1
Guo, X; Liu, H; Yu, FF	1
Guo, X; Ning, Y; Wang, X; Yang, L; Yu, F	1
Gong, H; Guo, M; Guo, Y; Li, H; Li, Y; Nima, C; Wang, J; Wang, W; Wei, B; Yang, L; Zhao, S	1
Bao, Y; Broadley, MR; Collings, R; Fairweather-Tait, SJ; Ford, D; Hesketh, JE; Hurst, R	1
Li, H; Li, Y; Wang, W; Yang, L; Zhang, B	1
Guo, X; Kang, LL; Li, WR; Lv, AL; Ren, FL; Shi, XW	1
Dai, XX; Du, XH; Lu Bai, G; Mo, XY; Xia Song, R; Xiong, YM; Yan Sun, W; Zou, XZ	1
Cheng, J; Deng, J; Hao, P; Hu, M; Huang, L; Lin, H; Liu, X; Long, W; Lu, F; Lv, B; Ma, S; Shen, S; Shi, Y; Wang, X; Wang, Y; Yang, X; Yang, Z; Zeng, M; Zhang, K; Zhou, B; Zhu, J	1
Guo, X; Liu, L; Ping, Z	1
Kang, PD; Li, L; Li, XB; Pei, FX; Shen, B; Yang, J; Yao, YF; Zhou, ZK	1
Caterson, B; Chen, JH; Guan, F; Hughes, C; Li, S; Song, D; Wang, W; Wang, ZL; Xue, S; Yang, H; Zhou, W; Zhou, X	1
Chen, C; Chen, JH; Li, S; Song, D; Wang, W; Wang, ZL; Xue, S; Yang, H; Zhou, X	1
Cao, J; Caterson, B; Chen, J; Fu, Q; Li, J; Li, S; Liu, F; Liu, J; Lu, M; Luo, M; Wang, J; Zhang, Z	1
Fu, Y; Li, Q; Meng, FG; Sun, LY; Wang, LH; Zhao, ZJ	1

Reviews

11 review(s) available for selenium and Kashin-Beck Disease

Article	Year
Status and potential diagnostic roles of essential trace elements in Kashin- Beck disease patients. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2022, Volume: 69 Topics: Copper; Fluorine; Humans; Iodine; Iron; Kashin-Beck Disease; Manganese; Selenium; Trace Elements; Zinc	2022
Progress of Selenium Deficiency in the Pathogenesis of Arthropathies and Selenium Supplement for Their Treatment. Biological trace element research, 2022, Volume: 200, Issue:10 Topics: Cartilage; Humans; Kashin-Beck Disease; Osteoarthritis; Oxidative Stress; Selenium	2022
Research Progress of Selenium-Enriched Foods. Nutrients, 2023, Sep-28, Volume: 15, Issue:19 Topics: Antioxidants; Food, Fortified; Humans; Kashin-Beck Disease; Selenium; Trace Elements	2023
Prevention and control strategies for children Kashin-Beck disease in China: A systematic review and meta-analysis. Medicine, 2019, Volume: 98, Issue:36 Topics: China; Edible Grain; Endemic Diseases; Female; Humans; Humic Substances; Kashin-Beck Disease; Male; Prospective Studies; Selenium; Water Supply	2019
Effects of five types of selenium supplementation for treatment of Kashin-Beck disease in children: a systematic review and network meta-analysis. BMJ open, 2018, 03-06, Volume: 8, Issue:3 Topics: Adolescent; Bone and Bones; Child; Child, Preschool; Dietary Supplements; Female; Humans; Kashin-Beck Disease; Male; Network Meta-Analysis; Radiography; Selenium; Selenium Compounds	2018
The effectiveness of treatments for Kashin-Beck disease: a systematic review and network meta-analysis. Clinical rheumatology, 2019, Volume: 38, Issue:12 Topics: Chondroitin; Dietary Supplements; Glucosamine; Humans; Kashin-Beck Disease; Pain Management; Selenium	2019
Salt-Rich Selenium for Prevention and Control Children with Kashin-Beck Disease: a Meta-analysis of Community-Based Trial. Biological trace element research, 2016, Volume: 170, Issue:1 Topics: China; Clinical Trials as Topic; Humans; Kashin-Beck Disease; Selenium; Sodium Chloride, Dietary	2016
Selenium and Iodine Levels in Subjects with Kashin-Beck Disease: a Meta-analysis. Biological trace element research, 2016, Volume: 170, Issue:1 Topics: Case-Control Studies; Cross-Sectional Studies; Humans; Iodine; Kashin-Beck Disease; Selenium	2016
Integrative Multivariate Logistic Regression Analysis of Risk Factors for Kashin-Beck disease. Biological trace element research, 2016, Volume: 174, Issue:2 Topics: Age of Onset; Female; Food Contamination; Food Preferences; Hair; Humans; Kashin-Beck Disease; Logistic Models; Male; Nitrogen; Protein Deficiency; Risk Factors; Selenium	2016
Zinc: the Other Suspected Environmental Factor in Kashin-Beck Disease in Addition to Selenium. Biological trace element research, 2017, Volume: 179, Issue:2 Topics: Cation Transport Proteins; Chondrocytes; DNA-Binding Proteins; Environmental Exposure; Humans; Kashin-Beck Disease; Osteochondrosis; Selenium; Soil Pollutants; Transcription Factor MTF-1; Transcription Factors; Zinc	2017
Selenium in human health and disease. Antioxidants & redox signaling, 2011, Apr-01, Volume: 14, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiomyopathies; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Enterovirus Infections; Fertility Agents; Health; Humans; Intestinal Absorption; Kashin-Beck Disease; Mutation; Neoplasms; Nutrition Policy; Nutritional Requirements; Selenium; Selenoproteins; Thyroid Hormones	2011

Trials

1 trial(s) available for selenium and Kashin-Beck Disease

Article	Year
Effects of the consumption of rice from non-KBD areas and selenium supplementation on the prevention and treatment of paediatric Kaschin-Beck disease: an epidemiological intervention trial in the Qinghai Province. Osteoarthritis and cartilage, 2014, Volume: 22, Issue:12 Topics: Child; China; Dietary Supplements; Female; Humans; Kashin-Beck Disease; Male; Oryza; Selenium	2014

Other Studies

67 other study(ies) available for selenium and Kashin-Beck Disease

Article	Year
Differences of selenium and other trace elements abundances between the Kaschin-Beck disease area and nearby non-Kaschin-Beck disease area, Shaanxi Province, China. Food chemistry, 2022, Mar-30, Volume: 373, Issue:Pt B Topics: China; Humans; Kashin-Beck Disease; Selenium; Soil; Trace Elements	2022
Mechanism of DNA methylation-mediated downregulation of O6-methylguanine-DNA methyltransferase in cartilage injury of Kashin-Beck disease. Rheumatology (Oxford, England), 2022, 08-03, Volume: 61, Issue:8 Topics: Cartilage, Articular; Chondrocytes; Decitabine; DNA; DNA Methylation; Down-Regulation; Guanine; Humans; Kashin-Beck Disease; RNA, Messenger; Selenium; T-2 Toxin	2022
Abnormal Level of Manganese, Iron, Iodine, and Selenium in the Hair of Children Living in Kashin-Beck Disease Endemic Areas. Biological trace element research, 2022, Volume: 200, Issue:10 Topics: Calcium; Child; Copper; Hair; Humans; Iodides; Iodine; Ions; Iron; Kashin-Beck Disease; Magnesium; Male; Manganese; Potassium; Selenium; Sodium	2022
Growth surveillance indices and Kashin-Beck Disease in children. Journal of medicine and life, 2022, Volume: 15, Issue:2 Topics: Calcium; Child; Humans; Kashin-Beck Disease; Manganese; Prognosis; Selenium	2022
Hydrochemical characteristics of surface waters and their relationships to the Kashin-Beck Disease in Longzi County, Tibet. Scientific reports, 2022, 05-12, Volume: 12, Issue:1 Topics: Humans; Kashin-Beck Disease; Selenium; Tibet; Trace Elements; Zinc	2022
Investigation of selenium nutritional status and dietary pattern among children in Kashin-Beck disease endemic areas in Shaanxi Province, China using duplicate portion sampling method. Environment international, 2022, Volume: 164 Topics: Child; China; Diet; Humans; Kashin-Beck Disease; Nutritional Status; Selenium	2022
The Role of Selenium-Mediated Notch/Hes1 Signaling Pathway in Kashin-Beck Disease Patients and Cartilage Injury Models. Biological trace element research, 2023, Volume: 201, Issue:6 Topics: Cartilage; Humans; Kashin-Beck Disease; Necrosis; Receptors, Notch; Selenium; Signal Transduction; Transcription Factor HES-1	2023
Association of oxidative stress and Kashin-Beck disease integrated Meta and Bioinformatics analysis. Osteoarthritis and cartilage, 2022, Volume: 30, Issue:12 Topics: Computational Biology; Cytochromes c; Glutathione; Humans; Kashin-Beck Disease; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidases; Selenium	2022
Dietary and drinking water intake of essential trace elements in a typical Kashin-Beck disease endemic area of Tibet, China. Environmental health : a global access science source, 2022, 09-16, Volume: 21, Issue:1 Topics: China; Copper; Diet; Drinking Water; Humans; Iron; Kashin-Beck Disease; Manganese; Molybdenum; Selenium; Tibet; Trace Elements; Zinc	2022
A Metabolomics Study of Feces Revealed That a Disturbance of Selenium-Centered Metabolic Bioprocess Was Involved in Kashin-Beck Disease, an Osteoarthropathy Endemic to China. Nutrients, 2023, Nov-02, Volume: 15, Issue:21 Topics: China; Humans; Kashin-Beck Disease; Metabolomics; Selenium; Trace Elements	2023
Expression and localization of the small proteoglycans decorin and biglycan in articular cartilage of Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency. Glycoconjugate journal, 2019, Volume: 36, Issue:6 Topics: Animals; Biglycan; Cartilage, Articular; Child; Chondrocytes; Decorin; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Kashin-Beck Disease; Male; Rats; Selenium; T-2 Toxin	2019
Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease. Biological trace element research, 2021, Volume: 199, Issue:3 Topics: Animals; Cartilage, Articular; Chondrocytes; Disease Models, Animal; HSP47 Heat-Shock Proteins; Kashin-Beck Disease; Rats; Selenium; T-2 Toxin	2021
The integrative analysis of DNA methylation and mRNA expression profiles confirmed the role of selenocompound metabolism pathway in Kashin-Beck disease. Cell cycle (Georgetown, Tex.), 2020, Volume: 19, Issue:18 Topics: Adult; Aged; Cartilage, Articular; Case-Control Studies; Cells, Cultured; DNA Methylation; Epigenome; Epigenomics; Female; Gene Expression Profiling; Gene Regulatory Networks; Humans; Kashin-Beck Disease; Male; Middle Aged; RNA, Messenger; Selenium; Transcriptome	2020
LncRNA MIAT regulated by selenium and T-2 toxin increases NF-κB-p65 activation, promoting the progress of Kashin-Beck Disease. Human & experimental toxicology, 2021, Volume: 40, Issue:5 Topics: Animals; Disease Models, Animal; Humans; Interleukin-1beta; Kashin-Beck Disease; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; RNA, Long Noncoding; Selenium; T-2 Toxin; Tumor Necrosis Factor-alpha	2021
Status and risks of selenium deficiency in a traditional selenium-deficient area in Northeast China. The Science of the total environment, 2021, Mar-25, Volume: 762 Topics: China; Fertilizers; Humans; Kashin-Beck Disease; Selenium; Soil	2021
Assessing the Health Loss from Kashin-Beck Disease and Its Relationship with Environmental Selenium in Qamdo District of Tibet, China. International journal of environmental research and public health, 2020, 12-22, Volume: 18, Issue:1 Topics: Hordeum; Humans; Kashin-Beck Disease; Selenium; Soil; Tibet	2020
Protective effect of chondroitin sulfate nano-selenium on chondrocyte of patients with Kashin-Beck disease. Journal of biomaterials applications, 2021, Volume: 35, Issue:10 Topics: Biocompatible Materials; Carbohydrate Sulfotransferases; Cartilage, Articular; Caspase 9; Cell Survival; Cells, Cultured; Chondrocytes; Chondroitin Sulfates; Humans; Kashin-Beck Disease; Male; Middle Aged; Mitochondria; Nanostructures; Selenium; Sulfotransferases; Up-Regulation	2021
Spatial distribution and determinants of health loss from Kashin-Beck disease in Bin County, Shaanxi Province, China. BMC public health, 2021, 02-19, Volume: 21, Issue:1 Topics: China; Endemic Diseases; Female; Humans; Kashin-Beck Disease; Male; Middle Aged; Selenium; Soil	2021
Reduction of Smad2 caused by oxidative stress leads to necrotic death of hypertrophic chondrocytes associated with an endemic osteoarthritis. Rheumatology (Oxford, England), 2021, 12-24, Volume: 61, Issue:1 Topics: Animals; Apoptosis; Case-Control Studies; Cell Line; Chondrocytes; Endemic Diseases; Hypertrophy; Kashin-Beck Disease; Male; Mice; Necrosis; Osteoarthritis; Oxidative Stress; Rats, Sprague-Dawley; Selenium; Smad2 Protein; Smad3 Protein	2021
[Evaluation of dietary diversity of rural residents in Arun Banner, a typical area of low selenium belt in China]. Wei sheng yan jiu = Journal of hygiene research, 2021, Volume: 50, Issue:3 Topics: China; Diet; Female; Humans; Kashin-Beck Disease; Male; Middle Aged; Rural Population; Selenium	2021
Downregulation of Insulin-Like Growth Factor-1 Receptor Mediates Chondrocyte Death and Matrix Degradation in Kashin-Beck Disease. Cartilage, 2021, Volume: 13, Issue:1_suppl Topics: Animals; Cartilage, Articular; Chondrocytes; Down-Regulation; Extracellular Matrix; Humans; Insulin-Like Growth Factor I; Kashin-Beck Disease; Mice; Rats; RNA, Messenger; Selenium	2021
Effectiveness of Selenium on Chondrocyte Glycoprotein Glycosylation Which Play Important Roles in the Pathogenesis of an Endemic Osteoarthritis, Kashin-Beck Disease. Biological trace element research, 2022, Volume: 200, Issue:4 Topics: Chondrocytes; Glycoproteins; Glycosylation; Humans; Kashin-Beck Disease; Osteoarthritis; Selenium	2022
Dysregulation of Transcription Profile of Selenoprotein in Patients with Kashin-Beck Disease and Its Effect on Se Deficiency-Induced Chondrocyte Apoptosis. Biological trace element research, 2022, Volume: 200, Issue:4 Topics: Apoptosis; Chondrocytes; Humans; Kashin-Beck Disease; Selenium; Selenoproteins	2022
Increased Chondrocyte Apoptosis in Kashin-Beck Disease and Rats Induced by T-2 Toxin and Selenium Deficiency. Biomedical and environmental sciences : BES, 2017, Volume: 30, Issue:5 Topics: Adolescent; Animals; Apoptosis; Biomarkers; Cartilage, Articular; Child; Chondrocytes; Female; Humans; Kashin-Beck Disease; Male; Matrilin Proteins; Models, Animal; Random Allocation; Rats; Rats, Sprague-Dawley; Selenium; T-2 Toxin	2017
Nutrients Other than Selenium Are Important for Promoting Children's Health in Kashin-Beck Disease Areas. Biological trace element research, 2018, Volume: 183, Issue:2 Topics: Child Health; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Kashin-Beck Disease; Male; Multivariate Analysis; Selenium	2018
Associations Between Selenium Content in Hair and Kashin-Beck Disease/Keshan Disease in Children in Northwestern China: a Prospective Cohort Study. Biological trace element research, 2018, Volume: 184, Issue:1 Topics: Child; Child, Preschool; China; Female; Hair; Humans; Kashin-Beck Disease; Male; Prospective Studies; Selenium	2018
Selenium status of children in Kashin-Beck disease endemic areas in Shaanxi, China: assessment with mercury. Environmental geochemistry and health, 2018, Volume: 40, Issue:2 Topics: Adolescent; Child; Child, Preschool; China; Diet; Dietary Exposure; Endemic Diseases; Female; Hair; Humans; Kashin-Beck Disease; Male; Mercury; Scalp; Selenium; Triticum	2018
Imbalance of dietary nutrients and the associated differentially expressed genes and pathways may play important roles in juvenile Kashin-Beck disease. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2018, Volume: 50 Topics: Adolescent; Child; Child, Preschool; Computational Biology; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Kashin-Beck Disease; Male; Nutrients; Retrospective Studies; Selenium; Software; Surveys and Questionnaires	2018
Gene Expression Profile of Hypertrophic Chondrocytes Treated with H Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2018, Mar-30, Volume: 33, Issue:1 Topics: Animals; Cell Differentiation; Cell Proliferation; Chondrocytes; Hydrogen Peroxide; Insulin; Kashin-Beck Disease; Mice; Oxidative Stress; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Signal Transduction; Transcriptome; Transferrin	2018
The study on polymorphisms of Sep15 and TrxR2 and the expression of AP-1 signaling pathway in Kashin-Beck disease. Bone, 2019, Volume: 120 Topics: Apoptosis; Case-Control Studies; Cell Line; Chondrocytes; Ethnicity; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Kashin-Beck Disease; Male; Middle Aged; Polymorphism, Single Nucleotide; Selenium; Selenoproteins; Signal Transduction; Thioredoxin Reductase 2; Transcription Factor AP-1	2019
The Importance of Se-Related Genes in the Chondrocyte of Kashin-Beck Disease Revealed by Whole Genomic Microarray and Network Analysis. Biological trace element research, 2019, Volume: 187, Issue:2 Topics: Adult; Aged; Cartilage, Articular; Chondrocytes; Female; Gene Expression Profiling; Gene Ontology; Gene Regulatory Networks; Genomics; Humans; Kashin-Beck Disease; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Selenium	2019
The study of GPX3 methylation in patients with Kashin-Beck Disease and its mechanism in chondrocyte apoptosis. Bone, 2018, Volume: 117 Topics: Apoptosis; Case-Control Studies; Cell Line; Chondrocytes; DNA Methylation; Female; Glutathione Peroxidase; Humans; Kashin-Beck Disease; Male; Middle Aged; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; RNA, Messenger; Selenium; Signal Transduction	2018
Expression Profiles of Selenium-Related Genes in Human Chondrocytes Exposed to T-2 Toxin and Deoxynivalenol. Biological trace element research, 2019, Volume: 190, Issue:2 Topics: Chondrocytes; Databases, Genetic; Dose-Response Relationship, Drug; Female; Forkhead Box Protein O1; Gene Expression Profiling; Humans; Kashin-Beck Disease; Male; Middle Aged; Selenium; Signal Transduction; Structure-Activity Relationship; T-2 Toxin; Trichothecenes; Tumor Suppressor Protein p53	2019
T-2 Toxin Induces Epiphyseal Plate Lesions via Decreased SECISBP2-Mediated Selenoprotein Expression in DA Rats, Exacerbated by Selenium Deficiency. Cartilage, 2021, Volume: 12, Issue:1 Topics: Animals; Cartilage, Articular; Disease Models, Animal; Growth Plate; Kashin-Beck Disease; Rats; RNA-Binding Proteins; Selenium; Selenoproteins; T-2 Toxin	2021
Selenium Content and/or T-2 Toxin Contamination of Cereals, Soil, and Children's Hair in Some Areas of Heilongjiang and Gansu Provinces, China. Biological trace element research, 2019, Volume: 191, Issue:2 Topics: Analysis of Variance; Child; China; Edible Grain; Enzyme-Linked Immunosorbent Assay; Female; Hair; Humans; Kashin-Beck Disease; Male; Risk Factors; Selenium; Software; Soil	2019
Decreased Expression of CHST-12, CHST-13, and UST in the Proximal Interphalangeal Joint Cartilage of School-Age Children with Kashin-Beck Disease: an Endemic Osteoarthritis in China Caused by Selenium Deficiency. Biological trace element research, 2019, Volume: 191, Issue:2 Topics: Cartilage, Articular; Child; Chondroitin Sulfates; Female; Humans; Kashin-Beck Disease; Male; Osteoarthritis; Selenium; Sulfotransferases	2019
Hair multi-bioelement profile of Kashin-Beck disease in the endemic regions of China. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2019, Volume: 54 Topics: Adolescent; Calcium; Child; Chromium; Hair; Humans; Iron; Kashin-Beck Disease; Manganese; Phosphorus; Retrospective Studies; Selenium; Titanium; Trace Elements	2019
Serious Selenium Deficiency in the Serum of Patients with Kashin-Beck Disease and the Effect of Nano-Selenium on Their Chondrocytes. Biological trace element research, 2020, Volume: 194, Issue:1 Topics: Adult; Arthritis, Rheumatoid; Chondrocytes; Chondroitin Sulfates; Female; Humans; Kashin-Beck Disease; Male; Middle Aged; Osteoarthritis; Selenium	2020
An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. Osteoarthritis and cartilage, 2013, Volume: 21, Issue:8 Topics: Animal Nutritional Physiological Phenomena; Animals; Cartilage, Articular; Chondrocytes; Dietary Proteins; Disease Models, Animal; Female; Growth Plate; Iodine; Kashin-Beck Disease; Male; Malnutrition; Necrosis; Rats; Rats, Sprague-Dawley; Rats, Wistar; Selenium; T-2 Toxin; Thyroxine; Tibia; Triiodothyronine; Weight Gain	2013
Oxidative stress and status of antioxidant enzymes in children with Kashin-Beck disease. Osteoarthritis and cartilage, 2013, Volume: 21, Issue:11 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Antioxidants; Cartilage, Articular; Case-Control Studies; Child; Child, Preschool; Chondrocytes; Deoxyguanosine; Female; Hair; Humans; Kashin-Beck Disease; Lipid Peroxidation; Male; Oxidative Stress; Proteoglycans; Selenium; Thiobarbiturates	2013
Increased levels of IL-6, IL-1β, and TNF-α in Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency. Rheumatology international, 2014, Volume: 34, Issue:7 Topics: Animals; Cartilage, Articular; Child; Disease Models, Animal; Female; Finger Phalanges; Gene Expression; Humans; Interleukin-1beta; Interleukin-6; Kashin-Beck Disease; Knee Joint; Male; Rats, Sprague-Dawley; Selenium; T-2 Toxin; Tumor Necrosis Factor-alpha	2014
Association study of polymorphisms in selenoprotein genes and Kashin-Beck disease and serum selenium/iodine concentration in a Tibetan population. PloS one, 2013, Volume: 8, Issue:8 Topics: Adult; Aged; Female; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Iodide Peroxidase; Iodine; Iodothyronine Deiodinase Type II; Kashin-Beck Disease; Male; Middle Aged; Polymorphism, Single Nucleotide; Selenium; Selenoproteins; Thioredoxin Reductase 2; Tibet	2013
Speciation, distribution, and bioavailability of soil selenium in the Tibetan Plateau Kashin-beck disease area-a case study in Songpan County, Sichuan Province, China. Biological trace element research, 2013, Volume: 156, Issue:1-3 Topics: Biological Availability; Crops, Agricultural; Endemic Diseases; Hordeum; Kashin-Beck Disease; Selenium; Soil; Tibet	2013
Expression profiles of genes involved in apoptosis and selenium metabolism in articular cartilage of patients with Kashin-Beck osteoarthritis. Gene, 2014, Feb-10, Volume: 535, Issue:2 Topics: Adult; Apoptosis; Cartilage, Articular; Case-Control Studies; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Kashin-Beck Disease; Male; Middle Aged; Osteoarthritis; Selenium; Signal Transduction; Transcriptome	2014
Synthesis and characterization of selenium-chondroitin sulfate nanoparticles. Carbohydrate polymers, 2012, Sep-01, Volume: 90, Issue:1 Topics: Apoptosis; Cell Line; Chondrocytes; Chondroitin Sulfates; Humans; Kashin-Beck Disease; Nanoparticles; Osteoarthritis; Selenium	2012
Constraint on selenium bioavailability caused by its geochemical behavior in typical Kaschin-Beck disease areas in Aba, Sichuan Province of China. The Science of the total environment, 2014, Sep-15, Volume: 493 Topics: China; Environmental Monitoring; Humans; Kashin-Beck Disease; Selenium; Soil; Soil Pollutants	2014
The role of mitochondria in T-2 toxin-induced human chondrocytes apoptosis. PloS one, 2014, Volume: 9, Issue:9 Topics: Antioxidants; Apoptosis; Cartilage, Articular; Caspase 3; Caspase 9; Cell Survival; Chondrocytes; Citrate (si)-Synthase; Cytochromes c; Electron Transport Complex III; Electron Transport Complex IV; Enzyme Activation; Fusarium; Glutathione; Humans; Kashin-Beck Disease; Middle Aged; Mitochondria; Reactive Oxygen Species; Selenium; T-2 Toxin	2014
Hair Selenium Levels of School Children in Kashin-Beck Disease Endemic Areas in Tibet, China. Biological trace element research, 2015, Volume: 168, Issue:1 Topics: Adolescent; Child; Endemic Diseases; Environment; Female; Hair; Humans; Kashin-Beck Disease; Male; Mass Spectrometry; Quality Control; Reproducibility of Results; Selenium; Sex Characteristics; Tibet	2015
The Prevention Effect of Selenium on Prevalence of Children Kaschin-Beck Disease in Active Endemic Areas in Qinghai Plateau. Biological trace element research, 2016, Volume: 169, Issue:1 Topics: Child; China; Dietary Supplements; Female; Hair; Humans; Kashin-Beck Disease; Male; Prevalence; Selenium	2016
T-2 Toxin Alters the Levels of Collagen II and Its Regulatory Enzymes MMPs/TIMP-1 in a Low-Selenium Rat Model of Kashin-Beck Disease. Biological trace element research, 2016, Volume: 169, Issue:2 Topics: Animals; Blotting, Western; Cartilage; Collagen Type II; Disease Models, Animal; Hindlimb; Immunohistochemistry; Kashin-Beck Disease; Male; Matrix Metalloproteinases; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Sternum; T-2 Toxin; Tissue Inhibitor of Metalloproteinase-1	2016
The Roles of the Interaction of BCL2-Antagonist/Killer 1, Apoptotic Peptidase Activating Factor 1 and Selenium in the Pathogenesis of Kashin-Beck Disease. Biological trace element research, 2016, Volume: 170, Issue:1 Topics: Apoptotic Protease-Activating Factor 1; bcl-2 Homologous Antagonist-Killer Protein; Cartilage, Articular; Cells, Cultured; Chondrocytes; Humans; Kashin-Beck Disease; Selenium	2016
Is It the Appropriate Time to Stop Applying Selenium Enriched Salt in Kashin-Beck Disease Areas in China? Nutrients, 2015, Jul-28, Volume: 7, Issue:8 Topics: Child; China; Cross-Sectional Studies; Deficiency Diseases; Dietary Supplements; Endemic Diseases; Female; Food, Fortified; Hair; Humans; Kashin-Beck Disease; Male; Retrospective Studies; Selenium; Sex Factors; Sodium Chloride, Dietary; Surveys and Questionnaires; Trace Elements	2015
Prevalence of Selenium, T-2 Toxin, and Deoxynivalenol in Kashin-Beck Disease Areas in Qinghai Province, Northwest China. Biological trace element research, 2016, Volume: 171, Issue:1 Topics: Adolescent; Child; China; Drinking Water; Female; Hair; Humans; Kashin-Beck Disease; Male; Selenium; Soil; T-2 Toxin; Trichothecenes; Triticum	2016
Effects of sodium selenite on c-Jun N-terminal kinase signalling pathway induced by oxidative stress in human chondrocytes and c-Jun N-terminal kinase expression in patients with Kashin-Beck disease, an endemic osteoarthritis. The British journal of nutrition, 2016, Volume: 115, Issue:9 Topics: Antioxidants; Apoptosis; Cell Survival; Chondrocytes; Down-Regulation; Glutathione Peroxidase; Humans; JNK Mitogen-Activated Protein Kinases; Kashin-Beck Disease; MAP Kinase Signaling System; Osteoarthritis; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Selenium; Signal Transduction; Sodium Selenite; tert-Butylhydroperoxide; Up-Regulation	2016
Selenium. Advances in nutrition (Bethesda, Md.), 2016, Volume: 7, Issue:2 Topics: Animals; Cardiomyopathies; Deficiency Diseases; Diabetes Mellitus, Type 2; Dietary Supplements; Energy Metabolism; Enterovirus Infections; Humans; Immunity, Innate; Kashin-Beck Disease; Neoplasms; Nutritional Requirements; Recommended Dietary Allowances; Selenium	2016
The roles of selenium, insulin-like growth factor binding protein 2 and suppressor of cytokine signaling 3 in the pathogenesis of Kashin-Beck disease. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2016, Volume: 21, Issue:5 Topics: Biomarkers, Pharmacological; Cartilage, Articular; Cells, Cultured; Chondrocytes; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Protein 2; Kashin-Beck Disease; Selenium; Suppressor of Cytokine Signaling 3 Protein	2016
Trace Element Levels in Scalp Hair of School Children in Shigatse, Tibet, an Endemic Area for Kaschin-Beck Disease (KBD). Biological trace element research, 2017, Volume: 180, Issue:1 Topics: Adolescent; Child; Female; Hair; Humans; Kashin-Beck Disease; Male; Scalp; Selenium; Tibet; Trace Elements; Zinc	2017
Environmental selenium in the Kaschin-Beck disease area, Tibetan Plateau, China. Environmental geochemistry and health, 2011, Volume: 33, Issue:5 Topics: Drinking Water; Environmental Monitoring; Epidemiological Monitoring; Humans; Kashin-Beck Disease; Prevalence; Selenium; Soil; Tibet	2011
[Transmission disequilibrium test for 15 short tandem repeat loci in Kashin-Beck disease and their interaction with low selenium]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:4 Topics: Adolescent; Adult; Alleles; Child; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Kashin-Beck Disease; Male; Microsatellite Repeats; Middle Aged; Pedigree; Selenium; Young Adult	2011
SNP and mRNA expression for glutathione peroxidase 4 in Kashin-Beck disease. The British journal of nutrition, 2012, Volume: 107, Issue:2 Topics: 3' Untranslated Regions; Case-Control Studies; China; Down-Regulation; Exons; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Glutathione Peroxidase; Haplotypes; Humans; Kashin-Beck Disease; Linkage Disequilibrium; Lymphocytes; Male; Middle Aged; Phospholipid Hydroperoxide Glutathione Peroxidase; Polymorphism, Single Nucleotide; RNA, Messenger; Selenium	2012
Genetic variants in the HLA-DRB1 gene are associated with Kashin-Beck disease in the Tibetan population. Arthritis and rheumatism, 2011, Volume: 63, Issue:11 Topics: Adolescent; Adult; Aged; Alleles; Asian People; Case-Control Studies; Child; Child, Preschool; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; HLA-DRB1 Chains; Humans; Iodine; Kashin-Beck Disease; Male; Middle Aged; Polymorphism, Single Nucleotide; Selenium; Tibet	2011
[Interaction of plasma selenium levels and D12S304 gene site in the pathogenesis of Kashin-Beck disease analyzed by multifactor dimensionality reduction software]. Wei sheng yan jiu = Journal of hygiene research, 2011, Volume: 40, Issue:4 Topics: Adolescent; Adult; Aged; Case-Control Studies; Child; China; Female; Gene-Environment Interaction; Genotype; Humans; Kashin-Beck Disease; Male; Middle Aged; Multifactor Dimensionality Reduction; Selenium; Software; Young Adult	2011
Preventive effects of supplemental selenium and selenium plus iodine on bone and cartilage development in rats fed with diet from Kashin-Beck disease endemic area. Biological trace element research, 2012, Volume: 146, Issue:2 Topics: Animals; Bone Development; Cartilage; Diet; Dietary Supplements; Drug Synergism; Endemic Diseases; Female; Femur; Growth Plate; Iodine; Kashin-Beck Disease; Male; Random Allocation; Rats; Rats, Wistar; Selenium; Thyroxine; Tibia; Time Factors; Triiodothyronine; Weight Gain	2012
Histopathology of chondronecrosis development in knee articular cartilage in a rat model of Kashin-Beck disease using T-2 toxin and selenium deficiency conditions. Rheumatology international, 2013, Volume: 33, Issue:1 Topics: Animal Feed; Animals; Body Weight; Cartilage Diseases; Cartilage, Articular; Chondrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione Peroxidase; Growth Plate; Kashin-Beck Disease; Male; Necrosis; Proteoglycans; Rats; Rats, Sprague-Dawley; Selenium; Stifle; T-2 Toxin	2013
Oxidant damage in Kashin-Beck disease and a rat Kashin-Beck disease model by employing T-2 toxin treatment under selenium deficient conditions. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2012, Volume: 30, Issue:8 Topics: Animals; Antioxidants; Cartilage; Cartilage, Articular; Catalase; Child; Child, Preschool; Disease Models, Animal; Glutathione Peroxidase; Humans; Kashin-Beck Disease; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Selenium; Superoxide Dismutase; T-2 Toxin; Thiobarbituric Acid Reactive Substances	2012
The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. Cells, tissues, organs, 2012, Volume: 196, Issue:3 Topics: Aggrecans; Biomarkers; Cells, Cultured; Chondrocytes; Collagen Type II; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Kashin-Beck Disease; Mycotoxins; Selenium; T-2 Toxin; Tissue Engineering; Trichothecenes	2012
T-2 toxin contamination in grains and selenium concentration in drinking water and grains in Kaschin-Beck disease endemic areas of Qinghai Province. Biological trace element research, 2012, Volume: 150, Issue:1-3 Topics: China; Drinking Water; Edible Grain; Endemic Diseases; Environmental Monitoring; Family Characteristics; Flour; Food Contamination; Food Storage; Health Surveys; Humans; Kashin-Beck Disease; Population Surveillance; Prevalence; Rural Health; Selenium; T-2 Toxin; Triticum; Water Pollution, Chemical; Water Supply	2012