selenic acid has been researched along with Disease Models, Animal in 20 studies
Selenic Acid: A strong dibasic acid with the molecular formula H2SeO4. Included under this heading is the acid form, and inorganic salts of dihydrogen selenium tetraoxide.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " KU showed increased bioavailability compared with UA in the tumor, liver, and plasma of a CT26 syngeneic mouse tumor xenograft model after oral administration, as determined by LC-MS/MS analysis." | 5.48 | Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer. ( Bae, WK; Choi, YJ; Chung, IJ; Gamage, C; Ha, HH; Hur, JS; Kim, H; Kim, KK; Kim, SK; Lee, JH; Lee, JY; Lee, KH; Paik, MJ; Park, MS; Park, SY; Taş, İ; Yang, Y; Yu, YH; Zhou, R, 2018) |
| " fumigatus ΔlaeA OE::metR strain still was unable to rescue the ΔlaeA phenotype to wildtype with regards gliotoxin synthesis and virulence in a zebrafish aspergillosis model." | 3.88 | Selenate sensitivity of a laeA mutant is restored by overexpression of the bZIP protein MetR in Aspergillus fumigatus. ( Huttenlocher, A; Jain, S; Kabbage, M; Keller, NP; Knox, BP; Palmer, JM; Sekonyela, R, 2018) |
| " In vitro, sodium selenate reduced tau phosphorylation in human neuroblastoma cells and reversed the increase in tau phosphorylation induced by the PP2A inhibitor, okadaic acid." | 3.78 | Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models. ( Chen, T; Corcoran, NM; Grundy, R; Hovens, CM; Jones, NC; Nguyen, T; O'Brien, TJ; Velakoulis, D, 2012) |
| "Obesity is often accompanied by dyslipidemia, high blood glucose, hypertension, atherosclerosis, and myocardial dysfunction." | 1.51 | Sodium Selenate Ameliorates Cardiac Injury Developed from High-Fat Diet in Mice through Regulation of Autophagy Activity. ( He, Z; Jiang, T; Xu, J; Xu, M; Xue, F; Zhang, S, 2019) |
| " KU showed increased bioavailability compared with UA in the tumor, liver, and plasma of a CT26 syngeneic mouse tumor xenograft model after oral administration, as determined by LC-MS/MS analysis." | 1.48 | Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer. ( Bae, WK; Choi, YJ; Chung, IJ; Gamage, C; Ha, HH; Hur, JS; Kim, H; Kim, KK; Kim, SK; Lee, JH; Lee, JY; Lee, KH; Paik, MJ; Park, MS; Park, SY; Taş, İ; Yang, Y; Yu, YH; Zhou, R, 2018) |
| "Lafora disease is caused by loss-of-function mutations in either the EPM2A or EPM2B genes." | 1.46 | Sodium selenate treatment improves symptoms and seizure susceptibility in a malin-deficient mouse model of Lafora disease. ( Sánchez, MP; Sánchez-Elexpuru, G; Serratosa, JM, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 17 (85.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 1 |
| Xu, J | 1 |
| He, Z | 1 |
| Xue, F | 1 |
| Jiang, T | 1 |
| Xu, M | 1 |
| Jin, N | 3 |
| Zhu, H | 1 |
| Liang, X | 1 |
| Huang, W | 1 |
| Xie, Q | 1 |
| Xiao, P | 1 |
| Ni, J | 3 |
| Liu, Q | 5 |
| Iqbal, J | 2 |
| Zhang, K | 2 |
| Zhao, Y | 2 |
| Shen, L | 2 |
| Van der Jeugd, A | 1 |
| Parra-Damas, A | 1 |
| Baeta-Corral, R | 1 |
| Soto-Faguás, CM | 1 |
| Ahmed, T | 1 |
| LaFerla, FM | 1 |
| Giménez-Llort, L | 1 |
| D'Hooge, R | 1 |
| Saura, CA | 1 |
| Jain, S | 1 |
| Sekonyela, R | 1 |
| Knox, BP | 1 |
| Palmer, JM | 1 |
| Huttenlocher, A | 1 |
| Kabbage, M | 1 |
| Keller, NP | 1 |
| Yang, Y | 1 |
| Bae, WK | 1 |
| Lee, JY | 1 |
| Choi, YJ | 1 |
| Lee, KH | 1 |
| Park, MS | 1 |
| Yu, YH | 1 |
| Park, SY | 1 |
| Zhou, R | 1 |
| Taş, İ | 1 |
| Gamage, C | 1 |
| Paik, MJ | 1 |
| Lee, JH | 1 |
| Chung, IJ | 1 |
| Kim, KK | 1 |
| Hur, JS | 1 |
| Kim, SK | 1 |
| Ha, HH | 1 |
| Kim, H | 1 |
| Chen, P | 1 |
| Wang, LX | 1 |
| Sui, XJ | 1 |
| Li, SM | 1 |
| Wang, Y | 1 |
| Ni, JZ | 2 |
| Shultz, SR | 3 |
| Wright, DK | 2 |
| Zheng, P | 2 |
| Stuchbery, R | 1 |
| Liu, SJ | 2 |
| Sashindranath, M | 1 |
| Medcalf, RL | 1 |
| Johnston, LA | 2 |
| Hovens, CM | 4 |
| Jones, NC | 3 |
| O'Brien, TJ | 4 |
| Dezsi, G | 1 |
| Braine, E | 1 |
| Nguyen, T | 3 |
| Corcoran, NM | 3 |
| Mayo, JN | 1 |
| Hudson, M | 1 |
| Brady, RD | 1 |
| Grills, BL | 1 |
| Romano, T | 1 |
| Wark, JD | 1 |
| McDonald, SJ | 1 |
| Zheng, L | 1 |
| Zhu, HZ | 1 |
| Wang, BT | 1 |
| Zhao, QH | 1 |
| Du, XB | 1 |
| Zheng, Y | 1 |
| Jiang, L | 1 |
| Zhang, Y | 1 |
| Sánchez-Elexpuru, G | 1 |
| Serratosa, JM | 1 |
| Sánchez, MP | 1 |
| Karabulut-Bulan, O | 1 |
| Bolkent, S | 2 |
| Yanardag, R | 2 |
| Bilgin-Sokmen, B | 1 |
| Martin, D | 1 |
| Hutter-Paier, B | 1 |
| Windisch, M | 1 |
| Nheu, L | 1 |
| Sundstrom, LE | 1 |
| Costello, AJ | 1 |
| van Eersel, J | 1 |
| Ke, YD | 1 |
| Liu, X | 1 |
| Delerue, F | 1 |
| Kril, JJ | 1 |
| Götz, J | 1 |
| Ittner, LM | 1 |
| Ghodbane, S | 1 |
| Amara, S | 1 |
| Arnaud, J | 1 |
| Garrel, C | 1 |
| Faure, H | 1 |
| Favier, A | 1 |
| Sakly, M | 1 |
| Abdelmelek, H | 1 |
| Velakoulis, D | 1 |
| Chen, T | 1 |
| Grundy, R | 1 |
| Ozdil, S | 1 |
| Koyuturk, M | 1 |
| Arbak, S | 1 |
| Chen, X | 1 |
| Mikhail, SS | 1 |
| Ding, YW | 1 |
| Yang, Gy | 1 |
| Bondoc, F | 1 |
| Yang, CS | 1 |
20 other studies available for selenic acid and Disease Models, Animal
| Article | Year |
|---|---|
Sodium Selenate Ameliorates Cardiac Injury Developed from High-Fat Diet in Mice through Regulation of Autophagy Activity.
Topics: Animals; Antioxidants; Autophagosomes; Autophagy; Cardiomyopathies; Cell Line; Diet, High-Fat; Disea | 2019 |
Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; beta Catenin; Disease Models, A | 2017 |
Effect of Sodium Selenate on Hippocampal Proteome of 3×Tg-AD Mice-Exploring the Antioxidant Dogma of Selenium against Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Disease Models, Animal; Gene Expression Regulation; Hippoc | 2018 |
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Dietary Su | 2018 |
Selenate sensitivity of a laeA mutant is restored by overexpression of the bZIP protein MetR in Aspergillus fumigatus.
Topics: Alleles; Animals; Aspergillosis; Aspergillus fumigatus; Basic-Leucine Zipper Transcription Factors; | 2018 |
Selenium positively affects the proteome of 3 × Tg-AD mice cortex by altering the expression of various key proteins: unveiling the mechanistic role of selenium in AD prevention.
Topics: Alzheimer Disease; Animals; Antioxidants; Cerebral Cortex; Disease Models, Animal; Gene Ontology; Ma | 2018 |
Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzofurans; Biological Availability; Cell Lin | 2018 |
Comparative Serum Proteomic Analysis of the Effects of Sodium Selenate on a Mouse Model of Alzheimer's Disease.
Topics: alpha 1-Antitrypsin; Alzheimer Disease; Animals; Disease Models, Animal; Glycoproteins; Haptoglobins | 2019 |
Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury.
Topics: Alzheimer Disease; Animals; Brain Injuries; Disease Models, Animal; Humans; Male; Phosphorylation; R | 2015 |
Sodium selenate retards epileptogenesis in acquired epilepsy models reversing changes in protein phosphatase 2A and hyperphosphorylated tau.
Topics: Animals; Anticonvulsants; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Electroencephalo | 2016 |
Sodium selenate treatment mitigates reduction of bone volume following traumatic brain injury in rats.
Topics: Animals; Antioxidants; Bone and Bones; Brain Injuries, Traumatic; Disease Models, Animal; Male; Rand | 2016 |
Sodium selenate regulates the brain ionome in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Brain; Disease Models, Animal; Glutathione Peroxidase; Ion | 2016 |
Sodium selenate treatment improves symptoms and seizure susceptibility in a malin-deficient mouse model of Lafora disease.
Topics: Animals; Antioxidants; Anxiety; Convulsants; Disease Models, Animal; Dual-Specificity Phosphatases; | 2017 |
The role of vitamin C, vitamin E, and selenium on cadmium-induced renal toxicity of rats.
Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Cadmium Chloride; Creatinine; Cytoprotec | 2008 |
Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Blotting, Western; Cell Line, Tumor; Cells, Cultur | 2010 |
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models.
Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Disease Models, Animal; Memory; Mice; Mice, Transgenic | 2010 |
Effect of selenium pre-treatment on plasma antioxidant vitamins A (retinol) and E (α-tocopherol) in static magnetic field-exposed rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Disease Models, Animal; Drug Administration Schedule; Elect | 2011 |
Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models.
Topics: Amygdala; Analysis of Variance; Animals; Antioxidants; Cell Line, Tumor; Convulsants; Disease Models | 2012 |
Protective effects of ascorbic acid, DL-alpha-tocopherol acetate, and sodium selenate on ethanol-induced gastric mucosal injury of rats.
Topics: alpha-Tocopherol; Animals; Ascorbic Acid; Blood Proteins; Disease Models, Animal; Ethanol; Female; G | 2004 |
Effects of vitamin E and selenium supplementation on esophageal adenocarcinogenesis in a surgical model with rats.
Topics: Absorption; Adenocarcinoma; alpha-Tocopherol; Anastomosis, Surgical; Animals; Anticarcinogenic Agent | 2000 |