selenic acid has been researched along with Alzheimer Disease in 12 studies
Selenic Acid: A strong dibasic acid with the molecular formula H2SeO4. Included under this heading is the acid form, and inorganic salts of dihydrogen selenium tetraoxide.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 12 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Jin, N | 3 |
Zhu, H | 1 |
Liang, X | 1 |
Huang, W | 1 |
Xie, Q | 1 |
Xiao, P | 1 |
Ni, J | 4 |
Liu, Q | 6 |
Iqbal, J | 2 |
Zhang, K | 2 |
Zhao, Y | 2 |
Shen, L | 3 |
Van der Jeugd, A | 1 |
Parra-Damas, A | 1 |
Baeta-Corral, R | 1 |
Soto-Faguás, CM | 1 |
Ahmed, T | 1 |
LaFerla, FM | 1 |
Giménez-Llort, L | 1 |
D'Hooge, R | 1 |
Saura, CA | 1 |
Cardoso, BR | 1 |
Roberts, BR | 1 |
Malpas, CB | 2 |
Vivash, L | 2 |
Genc, S | 2 |
Saling, MM | 2 |
Desmond, P | 2 |
Steward, C | 2 |
Hicks, RJ | 2 |
Callahan, J | 2 |
Brodtmann, A | 2 |
Collins, S | 2 |
Macfarlane, S | 2 |
Corcoran, NM | 3 |
Hovens, CM | 4 |
Velakoulis, D | 2 |
O'Brien, TJ | 3 |
Hare, DJ | 1 |
Bush, AI | 1 |
Chen, P | 2 |
Wang, LX | 1 |
Sui, XJ | 1 |
Li, SM | 1 |
Wang, Y | 2 |
Ni, JZ | 2 |
Wang, L | 1 |
Li, S | 1 |
Shultz, SR | 1 |
Wright, DK | 1 |
Zheng, P | 1 |
Stuchbery, R | 1 |
Liu, SJ | 1 |
Sashindranath, M | 1 |
Medcalf, RL | 1 |
Johnston, LA | 1 |
Jones, NC | 1 |
Zheng, L | 1 |
Zhu, HZ | 1 |
Wang, BT | 1 |
Zhao, QH | 1 |
Du, XB | 1 |
Zheng, Y | 1 |
Jiang, L | 1 |
Zhang, Y | 1 |
Martin, D | 1 |
Hutter-Paier, B | 1 |
Windisch, M | 1 |
Nguyen, T | 1 |
Nheu, L | 1 |
Sundstrom, LE | 1 |
Costello, AJ | 1 |
van Eersel, J | 1 |
Ke, YD | 1 |
Liu, X | 1 |
Delerue, F | 1 |
Kril, JJ | 1 |
Götz, J | 1 |
Ittner, LM | 1 |
2 trials available for selenic acid and Alzheimer Disease
Article | Year |
---|---|
Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Antioxidants; Central Nervous System; Dietary Supplements; Double-Blind Met | 2019 |
A Phase IIa Randomized Control Trial of VEL015 (Sodium Selenate) in Mild-Moderate Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognition; Diffusion | 2016 |
10 other studies available for selenic acid and Alzheimer Disease
Article | Year |
---|---|
Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; beta Catenin; Disease Models, A | 2017 |
Effect of Sodium Selenate on Hippocampal Proteome of 3×Tg-AD Mice-Exploring the Antioxidant Dogma of Selenium against Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Disease Models, Animal; Gene Expression Regulation; Hippoc | 2018 |
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Dietary Su | 2018 |
Selenium positively affects the proteome of 3 × Tg-AD mice cortex by altering the expression of various key proteins: unveiling the mechanistic role of selenium in AD prevention.
Topics: Alzheimer Disease; Animals; Antioxidants; Cerebral Cortex; Disease Models, Animal; Gene Ontology; Ma | 2018 |
Comparative Serum Proteomic Analysis of the Effects of Sodium Selenate on a Mouse Model of Alzheimer's Disease.
Topics: alpha 1-Antitrypsin; Alzheimer Disease; Animals; Disease Models, Animal; Glycoproteins; Haptoglobins | 2019 |
Phosphoproteomic profiling of selenate-treated Alzheimer's disease model cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cell Line; Cell Survival; Computational Biol | 2014 |
Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury.
Topics: Alzheimer Disease; Animals; Brain Injuries; Disease Models, Animal; Humans; Male; Phosphorylation; R | 2015 |
Sodium selenate regulates the brain ionome in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Brain; Disease Models, Animal; Glutathione Peroxidase; Ion | 2016 |
Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Blotting, Western; Cell Line, Tumor; Cells, Cultur | 2010 |
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models.
Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Disease Models, Animal; Memory; Mice; Mice, Transgenic | 2010 |