selenic acid has been researched along with Alzheimer Disease in 12 studies
Selenic Acid: A strong dibasic acid with the molecular formula H2SeO4. Included under this heading is the acid form, and inorganic salts of dihydrogen selenium tetraoxide.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, N | 3 |
| Zhu, H | 1 |
| Liang, X | 1 |
| Huang, W | 1 |
| Xie, Q | 1 |
| Xiao, P | 1 |
| Ni, J | 4 |
| Liu, Q | 6 |
| Iqbal, J | 2 |
| Zhang, K | 2 |
| Zhao, Y | 2 |
| Shen, L | 3 |
| Van der Jeugd, A | 1 |
| Parra-Damas, A | 1 |
| Baeta-Corral, R | 1 |
| Soto-Faguás, CM | 1 |
| Ahmed, T | 1 |
| LaFerla, FM | 1 |
| Giménez-Llort, L | 1 |
| D'Hooge, R | 1 |
| Saura, CA | 1 |
| Cardoso, BR | 1 |
| Roberts, BR | 1 |
| Malpas, CB | 2 |
| Vivash, L | 2 |
| Genc, S | 2 |
| Saling, MM | 2 |
| Desmond, P | 2 |
| Steward, C | 2 |
| Hicks, RJ | 2 |
| Callahan, J | 2 |
| Brodtmann, A | 2 |
| Collins, S | 2 |
| Macfarlane, S | 2 |
| Corcoran, NM | 3 |
| Hovens, CM | 4 |
| Velakoulis, D | 2 |
| O'Brien, TJ | 3 |
| Hare, DJ | 1 |
| Bush, AI | 1 |
| Chen, P | 2 |
| Wang, LX | 1 |
| Sui, XJ | 1 |
| Li, SM | 1 |
| Wang, Y | 2 |
| Ni, JZ | 2 |
| Wang, L | 1 |
| Li, S | 1 |
| Shultz, SR | 1 |
| Wright, DK | 1 |
| Zheng, P | 1 |
| Stuchbery, R | 1 |
| Liu, SJ | 1 |
| Sashindranath, M | 1 |
| Medcalf, RL | 1 |
| Johnston, LA | 1 |
| Jones, NC | 1 |
| Zheng, L | 1 |
| Zhu, HZ | 1 |
| Wang, BT | 1 |
| Zhao, QH | 1 |
| Du, XB | 1 |
| Zheng, Y | 1 |
| Jiang, L | 1 |
| Zhang, Y | 1 |
| Martin, D | 1 |
| Hutter-Paier, B | 1 |
| Windisch, M | 1 |
| Nguyen, T | 1 |
| Nheu, L | 1 |
| Sundstrom, LE | 1 |
| Costello, AJ | 1 |
| van Eersel, J | 1 |
| Ke, YD | 1 |
| Liu, X | 1 |
| Delerue, F | 1 |
| Kril, JJ | 1 |
| Götz, J | 1 |
| Ittner, LM | 1 |
2 trials available for selenic acid and Alzheimer Disease
| Article | Year |
|---|---|
Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Antioxidants; Central Nervous System; Dietary Supplements; Double-Blind Met | 2019 |
A Phase IIa Randomized Control Trial of VEL015 (Sodium Selenate) in Mild-Moderate Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognition; Diffusion | 2016 |
10 other studies available for selenic acid and Alzheimer Disease
| Article | Year |
|---|---|
Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; beta Catenin; Disease Models, A | 2017 |
Effect of Sodium Selenate on Hippocampal Proteome of 3×Tg-AD Mice-Exploring the Antioxidant Dogma of Selenium against Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Disease Models, Animal; Gene Expression Regulation; Hippoc | 2018 |
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Dietary Su | 2018 |
Selenium positively affects the proteome of 3 × Tg-AD mice cortex by altering the expression of various key proteins: unveiling the mechanistic role of selenium in AD prevention.
Topics: Alzheimer Disease; Animals; Antioxidants; Cerebral Cortex; Disease Models, Animal; Gene Ontology; Ma | 2018 |
Comparative Serum Proteomic Analysis of the Effects of Sodium Selenate on a Mouse Model of Alzheimer's Disease.
Topics: alpha 1-Antitrypsin; Alzheimer Disease; Animals; Disease Models, Animal; Glycoproteins; Haptoglobins | 2019 |
Phosphoproteomic profiling of selenate-treated Alzheimer's disease model cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cell Line; Cell Survival; Computational Biol | 2014 |
Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury.
Topics: Alzheimer Disease; Animals; Brain Injuries; Disease Models, Animal; Humans; Male; Phosphorylation; R | 2015 |
Sodium selenate regulates the brain ionome in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Brain; Disease Models, Animal; Glutathione Peroxidase; Ion | 2016 |
Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Blotting, Western; Cell Line, Tumor; Cells, Cultur | 2010 |
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models.
Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Disease Models, Animal; Memory; Mice; Mice, Transgenic | 2010 |