Page last updated: 2024-08-23

selegiline and Neurodegenerative Diseases

selegiline has been researched along with Neurodegenerative Diseases in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's9 (50.00)29.6817
2010's5 (27.78)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Bolognesi, ML; Cavalli, A; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tumiatti, V1
Borges, F; Fonseca, A; Gaspar, A; Milhazes, N; Reis, J; Uriarte, E; Viña, D1
Legoabe, LJ; Petzer, A; Petzer, JP1
Akkari, R; Borrmann, T; Brunschweiger, A; Drabczyńska, A; Hockemeyer, J; Kieć-Kononowicz, K; Koch, P; Köse, M; Küppers, P; Müller, CE; Radjainia, H; Schlenk, M1
Adolph, O; Appenroth, D; Enzensperger, C; Fleck, C; Föhr, KJ; Gaube, F; Lehmann, J; Otto, R; Penzis, R; Robaa, D; Warncke, P; Winckler, T1
Chew, ZX; Chye, SM; Koh, RY; Lim, CL; Ling, APK; Ng, KY1
Maruyama, W; Naoi, M; Shamoto-Nagai, M1
Ferdinandy, P; Fürst, S; Gyires, K; Miklya, I; Muraoka, S; Yoneda, F1
Klivényi, P; Rákóczi, K; Vécsei, L1
Miklya, I1
Schneemilch, C1
Brown-Borg, H; Carlson, EC; Ebadi, M; El ReFaey, H; Ren, J; Sharma, S; Shavali, S1
Jenei, V; Magyar, K; Pálfi, M; Szöko, E1
Mackowiak, A; Müller, T; Przuntek, H; Rieks, M1
Czub, M; Czub, S; Gerlach, M; Gosztonyi, G; Koutsilieri, E; Müller, JG; Riederer, P; Sopper, S; ter Meulen, V1
Arányi, P; Baranyi, A; Erdö, F; Takács, J1
Chalmers-Redman, RM; Elstner, M; Jagodzinski, FB; Leesch, W; Stupak, DP; Sugrue, MM; Tatton, NA; Tatton, WG1
Bhavnani, BR; Thomas, P; Thomas, T1

Reviews

7 review(s) available for selegiline and Neurodegenerative Diseases

ArticleYear
Multi-target-directed ligands to combat neurodegenerative diseases.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Calcium Channel Blockers; Chelating Agents; Cholinesterase Inhibitors; Humans; Huntington Disease; Ligands; Multiple Sclerosis; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurotransmitter Agents; Parkinson Disease; Plaque, Amyloid

2008
Neuroprotective Function of Rasagiline and Selegiline, Inhibitors of Type B Monoamine Oxidase, and Role of Monoamine Oxidases in Synucleinopathies.
    International journal of molecular sciences, 2022, Sep-21, Volume: 23, Issue:19

    Topics: alpha-Synuclein; Glial Cell Line-Derived Neurotrophic Factors; Humans; Indans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Neuroprotection; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Selegiline; Synucleinopathies

2022
[Neuroprotection in Parkinson's disease and other neurodegenerative disorders: preclinical and clinical findings].
    Ideggyogyaszati szemle, 2009, Jan-30, Volume: 62, Issue:1-2

    Topics: Animals; Creatine; Dopamine Agonists; Glatiramer Acetate; Humans; Indans; Kynurenic Acid; Micronutrients; Nerve Degeneration; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Peptides; Selegiline; Tocopherols; Ubiquinone

2009
[Slowing the age-induced decline of brain function with prophylactic use of (-)-deprenyl (Selegiline, Jumex). Current international view and conclusions 25 years after the Knoll's proposal].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2009, Volume: 11, Issue:4

    Topics: Aging; Apoptosis; Brain; Cell Culture Techniques; Humans; Mental Disorders; Neurodegenerative Diseases; Neuroprotective Agents; Selegiline

2009
Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases.
    Current drug targets, 2006, Volume: 7, Issue:11

    Topics: Animals; Humans; Nervous System Diseases; Neurodegenerative Diseases; Selegiline

2006
Deprenyl: from chemical synthesis to neuroprotection.
    Journal of neural transmission. Supplementum, 2006, Issue:71

    Topics: Animals; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Selegiline

2006
Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling.
    Journal of neural transmission. Supplementum, 2000, Issue:60

    Topics: Animals; Apoptosis; Brain; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Selegiline; Signal Transduction

2000

Other Studies

11 other study(ies) available for selegiline and Neurodegenerative Diseases

ArticleYear
Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors.
    Bioorganic & medicinal chemistry letters, 2011, Jan-15, Volume: 21, Issue:2

    Topics: Animals; Cell Line; Chromones; Humans; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Protein Isoforms; Structure-Activity Relationship

2011
Selected chromone derivatives as inhibitors of monoamine oxidase.
    Bioorganic & medicinal chemistry letters, 2012, Sep-01, Volume: 22, Issue:17

    Topics: Benzopyrans; Chromones; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Parkinson Disease; Protein Isoforms; Recombinant Proteins; Structure-Activity Relationship

2012
1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; CHO Cells; Cricetulus; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Purinergic P1 Receptor Antagonists; Purines; Xanthines

2013
Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders.
    Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16

    Topics: Animals; Carbolines; Cholinesterase Inhibitors; Computational Biology; Excitatory Amino Acid Antagonists; Humans; Indicators and Reagents; Ligands; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2015
The Role of Monoamine Oxidase B Inhibitors in the Treatment of Parkinson's Disease - An Update.
    CNS & neurological disorders drug targets, 2023, Volume: 22, Issue:3

    Topics: Antiparkinson Agents; Dopamine; Dopamine Agents; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Parkinson Disease; Selegiline

2023
Geroprotection in the future. In memoriam of Joseph Knoll: The selegiline story continues.
    European journal of pharmacology, 2020, Feb-05, Volume: 868

    Topics: Aging; Brain; Drug Development; Geriatrics; History, 20th Century; Humans; Life Expectancy; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Selegiline

2020
[General anaesthesia for neurological diseases].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2010, Volume: 45, Issue:5

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Autonomic Nervous System; Brain; Bromocriptine; Dopamine Agonists; Humans; Intubation; Levodopa; Monoamine Oxidase Inhibitors; Muscle Relaxants, Central; Nervous System Diseases; Neurodegenerative Diseases; Neurosurgery; Parkinson Disease; Piperidines; Premedication; Preoperative Care; Propofol; Remifentanil; Selegiline; Stereotaxic Techniques; Syndrome

2010
Selegiline reduces cisplatin-induced neuronal death in neuroblastoma cells.
    Neurological research, 2008, Volume: 30, Issue:4

    Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cisplatin; Drug Interactions; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neuroblastoma; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Selegiline; Time Factors

2008
Effects of Selegiline in a retroviral rat model for neurodegenerative disease.
    Journal of neurovirology, 1999, Volume: 5, Issue:5

    Topics: Animals; Animals, Newborn; Brain; Histocompatibility Antigens Class II; Humans; Leukemia Virus, Murine; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Rats; Rats, Inbred F344; Retroviridae Infections; RNA, Viral; Selegiline; Tumor Virus Infections

1999
Different neurorescue profiles of selegiline and p-fluoro-selegiline in gerbils.
    Neuroreport, 2000, Aug-03, Volume: 11, Issue:11

    Topics: Animals; Brain Ischemia; Cell Survival; Dose-Response Relationship, Drug; Fluorine Compounds; Gerbillinae; Hippocampus; Male; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Pyramidal Cells; Reperfusion Injury; Selegiline

2000
Inhibition of human LDL oxidation by the neuroprotective drug l-deprenyl.
    Neurological research, 2002, Volume: 24, Issue:2

    Topics: Adult; Antioxidants; Arteriosclerosis; Blood; Copper; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Plasma; Postmenopause; Selegiline; Sex Characteristics

2002