Page last updated: 2024-08-23

selegiline and Depression, Involutional

selegiline has been researched along with Depression, Involutional in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.23)18.2507
2000's18 (58.06)29.6817
2010's11 (35.48)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Birkenhager, TK; Caiazza, C; Cattaneo, CI; de Bartolomeis, A; Fornaro, M; Gillman, K; Iasevoli, F; Rossano, F; Ruhé, HG; Sobrino, A; Solini, N; Stahl, S; Van den Eynde, V; Vellucci, A; Zotti, N1
Citrome, L; Goldberg, JF; Portland, KB1
Craig Nelson, J; Jang, S; Jung, S; Kimberly, BP; Pae, C; Patkar, AA1
Jang, S; Jung, S; Nelson, JC; Pae, CU; Patkar, AA; Portland, KB1
Azzaro, AJ; DelBello, MP; Emslie, G; Hochadel, TJ; Katic, A; Khan, A; Portland, KB1
Byerly, MJ; Emslie, GJ; Mayes, TL; Nakonezny, PA1
Bied, AM; Kim, J; Schwartz, TL1
Cristancho, MA; Thase, ME1
Miklya, I1
DelBello, MP; Nandagopal, JJ1
Kostenko, O; Malone, D; Wimbiscus, M1
George, TP; McKee, SA; Weinberger, AH1
Alexopoulos, GS1
Amsterdam, JD; Bodkin, JA2
Robinson, DS1
Gaszner, P; Miklya, I2
Gorman, JM1
Masand, PS; Pae, CU; Patkar, AA1
Feiger, AD; Rickels, K; Robinson, DS; Rynn, MA; Zimbroff, DL1
Frampton, JE; Plosker, GL2
Tobin, M1
Amsterdam, JD; Robinson, DS1
Azzaro, AJ; Campbell, BJ; Gilmor, ML; Moonsammy, G; Oren, DA; Robinson, DS; Yang, Y1
Carlat, DJ1
Amsterdam, JD; Campbell, BJ; Clayton, AH; Favit, A; Moonsammy, G; Piontek, CM; Yang, Y1
Chari, G; Gold, M; Hauser, RA; Zesiewicz, TA1
Bilbao Garay, J; Castilla Castellano, V; Dhimes Tejada, P; Mesa Plaza, N1

Reviews

16 review(s) available for selegiline and Depression, Involutional

ArticleYear
Efficacy and safety of selegiline across different psychiatric disorders: A systematic review and meta-analysis of oral and transdermal formulations.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2023, Volume: 72

    Topics: Attention Deficit Disorder with Hyperactivity; Depressive Disorder, Major; Humans; Methylphenidate; Monoamine Oxidase Inhibitors; Selegiline

2023
Placing transdermal selegiline for major depressive disorder into clinical context: number needed to treat, number needed to harm, and likelihood to be helped or harmed.
    Journal of affective disorders, 2013, Volume: 151, Issue:2

    Topics: Administration, Cutaneous; Antidepressive Agents; Biomedical Research; Depressive Disorder, Major; Humans; Randomized Controlled Trials as Topic; Research Design; Selegiline

2013
Efficacy and safety of selegiline transdermal system (STS) for the atypical subtype of major depressive disorder: pooled analysis of 5 short-term, placebo-controlled trials.
    CNS spectrums, 2014, Volume: 19, Issue:4

    Topics: Administration, Cutaneous; Adult; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Psychophysiologic Disorders; Randomized Controlled Trials as Topic; Selegiline; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Weight Loss

2014
A critical appraisal of the selegiline transdermal system for major depressive disorder.
    Expert review of clinical pharmacology, 2015, Volume: 8, Issue:6

    Topics: Administration, Cutaneous; Antidepressive Agents; Depressive Disorder, Major; Drug Liberation; Humans; Hypertension; Medication Adherence; Selegiline; Transdermal Patch

2015
Critical appraisal of selegiline transdermal system for major depressive disorder.
    Expert opinion on drug delivery, 2016, Volume: 13, Issue:5

    Topics: Administration, Cutaneous; Depressive Disorder, Major; Humans; Monoamine Oxidase Inhibitors; Selegiline; Skin Absorption; Transdermal Patch

2016
The significance of selegiline/(-)-deprenyl after 50 years in research and therapy (1965-2015).
    Molecular psychiatry, 2016, Volume: 21, Issue:11

    Topics: Aging; Alzheimer Disease; Animals; Brain; Catecholamines; Depressive Disorder, Major; Dopamine; History, 20th Century; Humans; Monoamine Oxidase; Parkinson Disease; Phenethylamines; Rats; Selegiline

2016
Selegiline transdermal system: a novel treatment option for major depressive disorder.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:10

    Topics: Administration, Cutaneous; Amyloid beta-Peptides; Animals; Clinical Trials as Topic; Depressive Disorder, Major; Humans; Randomized Controlled Trials as Topic; Selegiline; Treatment Outcome

2009
MAO inhibitors: risks, benefits, and lore.
    Cleveland Clinic journal of medicine, 2010, Volume: 77, Issue:12

    Topics: Administration, Cutaneous; Antidepressive Agents; Blood Pressure; Cheese; Depressive Disorder, Major; Feeding Behavior; Food-Drug Interactions; Humans; Hypertension; Monoamine Oxidase Inhibitors; Myocardium; Risk Factors; Selegiline; Tyramine

2010
The use of the synthetic enhancer substances (-)-deprenyl and (-)-BPAP in major depression.
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2004, Volume: 6, Issue:4

    Topics: Benzofurans; Catecholamines; Depressive Disorder, Major; Humans; Mesencephalon; Neuroprotective Agents; Selegiline; Serotonin Agents; Tryptamines

2004
Major depression and the synthetic enhancer substances, (-)-deprenyl and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:1

    Topics: Animals; Benzofurans; Depressive Disorder, Major; Humans; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Selegiline; Tryptamines

2006
Transdermal selegiline: the new generation of monoamine oxidase inhibitors.
    CNS spectrums, 2006, Volume: 11, Issue:5

    Topics: Administration, Cutaneous; Depressive Disorder, Major; Drug Interactions; Humans; Monoamine Oxidase Inhibitors; Phenelzine; Selegiline; Tranylcypromine

2006
The selegiline transdermal system in major depressive disorder: a systematic review of safety and tolerability.
    Journal of affective disorders, 2008, Volume: 105, Issue:1-3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Humans; Hypertension; Hypotension, Orthostatic; Male; Middle Aged; Monoamine Oxidase Inhibitors; Selegiline; Serotonin Syndrome; Sexual Dysfunction, Physiological; Sleep Initiation and Maintenance Disorders

2008
Treatment effects of selegiline transdermal system on symptoms of major depressive disorder: a meta-analysis of short-term, placebo-controlled, efficacy trials.
    Psychopharmacology bulletin, 2007, Volume: 40, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Placebos; Randomized Controlled Trials as Topic; Selegiline

2007
Symptoms of sexual dysfunction in patients treated for major depressive disorder: a meta-analysis comparing selegiline transdermal system and placebo using a patient-rated scale.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:12

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Placebos; Randomized Controlled Trials as Topic; Selegiline; Sexual Dysfunction, Physiological; Sexual Dysfunctions, Psychological

2007
Current issues in depression in Parkinson's disease.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1999,Spring, Volume: 7, Issue:2

    Topics: Aged; Antidepressive Agents; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Parkinson Disease; Psychomotor Performance; Selective Serotonin Reuptake Inhibitors; Selegiline

1999
[Serotonin syndrome: report of a fatal case and review of the literature].
    Revista clinica espanola, 2002, Volume: 202, Issue:4

    Topics: Aged; Antiparkinson Agents; Carbidopa; Depressive Disorder, Major; Drug Combinations; Drug Synergism; Fatal Outcome; Fluoxetine; Humans; Levodopa; Male; Parkinson Disease; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin Syndrome

2002

Trials

6 trial(s) available for selegiline and Depression, Involutional

ArticleYear
Predictors of relapse in patients with major depressive disorder in a 52-week, fixed dose, double blind, randomized trial of selegiline transdermal system (STS).
    Journal of affective disorders, 2013, Volume: 151, Issue:3

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Monoamine Oxidase Inhibitors; Proportional Hazards Models; Recurrence; Risk Factors; Selegiline

2013
A double-blind, placebo-controlled study of selegiline transdermal system in depressed adolescents.
    Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:6

    Topics: Administration, Cutaneous; Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Selegiline; Severity of Illness Index; Transdermal Patch; Treatment Outcome

2014
Differences in smoking expectancies in smokers with and without a history of major depression.
    Addictive behaviors, 2011, Volume: 36, Issue:4

    Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Psychiatric Status Rating Scales; Selegiline; Sex Factors; Smoking; Smoking Cessation; Surveys and Questionnaires; Young Adult

2011
Transdermal selegiline in major depression: a double-blind, placebo-controlled, parallel-group study in outpatients.
    The American journal of psychiatry, 2002, Volume: 159, Issue:11

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Selegiline; Treatment Outcome

2002
Selegiline transdermal system for the treatment of major depressive disorder: an 8-week, double-blind, placebo-controlled, flexible-dose titration trial.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:9

    Topics: Administration, Cutaneous; Adult; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Monoamine Oxidase Inhibitors; Personality Inventory; Placebos; Psychiatric Status Rating Scales; Selegiline; Sleep Initiation and Maintenance Disorders; Treatment Outcome

2006
Selegiline transdermal system in the prevention of relapse of major depressive disorder: a 52-week, double-blind, placebo-substitution, parallel-group clinical trial.
    Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:6

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Delivery Systems; Female; Humans; Kaplan-Meier Estimate; Male; Monoamine Oxidase Inhibitors; Patient Compliance; Patient Dropouts; Psychiatric Status Rating Scales; Secondary Prevention; Selegiline; Time Factors; Treatment Outcome

2006

Other Studies

9 other study(ies) available for selegiline and Depression, Involutional

ArticleYear
Predicting placebo response in adolescents with major depressive disorder: The Adolescent Placebo Impact Composite Score (APICS).
    Journal of psychiatric research, 2015, Volume: 68

    Topics: Adolescent; Child; Depressive Disorder, Major; Female; Humans; Male; Models, Statistical; Neuroprotective Agents; Outcome Assessment, Health Care; Placebo Effect; Probability; Randomized Controlled Trials as Topic; Selegiline; Sensitivity and Specificity; Transdermal Patch

2015
Pharmacotherapy for late-life depression.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:1

    Topics: Administration, Cutaneous; Adult; Age Factors; Aged; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Humans; Monoamine Oxidase Inhibitors; Placebo Effect; Practice Guidelines as Topic; Psychotherapy; Selegiline; Treatment Outcome

2011
Monoamine oxidase inhibitors: a new generation.
    Psychopharmacology bulletin, 2002,Summer, Volume: 36, Issue:3

    Topics: Administration, Cutaneous; Antidepressive Agents; Depression; Depressive Disorder, Major; Humans; Monoamine Oxidase Inhibitors; Selegiline

2002
Leading the way: advances in the diagnosis, treatment, and management of neuropsychiatric illnesses.
    CNS spectrums, 2006, Volume: 11, Issue:5

    Topics: Administration, Cutaneous; Administration, Topical; Brain; Depressive Disorder, Major; Humans; Mental Disorders; Monoamine Oxidase Inhibitors; Phenelzine; Psychiatry; Selegiline; Somatoform Disorders; Tranylcypromine

2006
Transdermal selegiline (Emsam).
    The Medical letter on drugs and therapeutics, 2006, May-22, Volume: 48, Issue:1235

    Topics: Administration, Cutaneous; Antiparkinson Agents; Clinical Trials as Topic; Depressive Disorder, Major; Double-Blind Method; Drug Interactions; Humans; Monoamine Oxidase Inhibitors; Parkinson Disease; Selegiline

2006
Selegiline transdermal system: in the treatment of major depressive disorder.
    Drugs, 2007, Volume: 67, Issue:2

    Topics: Administration, Cutaneous; Adult; Depressive Disorder, Major; Drug Interactions; Female; Humans; Male; Monoamine Oxidase Inhibitors; Selegiline

2007
Psychopharmacology column: why choose selegiline transdermal system for refractory depression?
    Issues in mental health nursing, 2007, Volume: 28, Issue:2

    Topics: Administration, Cutaneous; Antidepressive Agents; Depressive Disorder, Major; Drug Interactions; Humans; Monoamine Oxidase Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Selegiline; Treatment Outcome; Tyramine

2007
Selegiline transdermal system in major depressive disorder: profile report.
    CNS drugs, 2007, Volume: 21, Issue:6

    Topics: Administration, Cutaneous; Area Under Curve; Depressive Disorder, Major; Diarrhea; Drug Administration Schedule; Half-Life; Headache; Humans; Monoamine Oxidase Inhibitors; Selegiline; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Xerostomia

2007
Commentary on the treatment effects of selegiline transdermal system on symptoms of major depressive disorder: a meta-analysis of short-term, placebo-controlled, efficacy trials.
    Psychopharmacology bulletin, 2007, Volume: 40, Issue:3

    Topics: Antidepressive Agents; Depressive Disorder, Major; Female; Humans; Male; Monoamine Oxidase Inhibitors; Selegiline

2007