Page last updated: 2024-08-23

selegiline and Brain Ischemia

selegiline has been researched along with Brain Ischemia in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (22.22)18.2507
2000's11 (61.11)29.6817
2010's2 (11.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Ahmari, M; Gharbavi, M; Hosseini, MJ; Jafari-Anarkoli, I; Mahmoudi, J; Sharafi, A1
Ahmadi, R; Amini-Khoei, H; Bagheri, N; Mobini, GR; Mokhtari, T; Sabzevary-Ghahfarokhi, M; Saghaei, E1
Abdelsalam, RM; Atia, AS; Seif-El-Nasr, M1
Magyar, K; Nagy, Z; Simon, L; Szilágyi, G; Wappler, E1
Feng, JJ; Li, C; Wu, YP; Zhang, GY1
Johansson, BB1
Aráujo, DT; Cunha, GM; Maia, FD; Pitombeira, BS; Viana, GS1
Ann, HS; Jang, KJ; Jhoo, JH; Jhoo, WK; Kim, HC; Kim, WK; Kim, YS; Kwon, YS; Nabeshima, T; Shin, EJ; Wie, MB1
Krieglstein, J; Schilling, M; Semkova, I; Wolz, P1
Ballabriga, J; Ferrer, I; Pellisé, A1
Ekblom, J; Garpenstrand, H; Oreland, L; Prince, JA; Tottmar, O1
Ekblom, J; Oreland, L; Tottmar, O1
Arányi, P; Baranyi, A; Erdö, F; Takács, J1
Haapalinna, A; Jolkkonen, J; Kuhmonen, J; Sivenius, J1
Haapalinna, A; Jolkkonen, J; Kauppinen, R; Nyman, L; Sivenius, J1
Haapalinna, A; Jolkkonen, J; Puurunen, K; Sirviö, J; Sivenius, J1
Bolay, H; Dalkara, T; Gürsoy-Ozdemir, Y; Saribaş, O; Söylemezoglu, F; Unal, I1
Bori, Z; Nagy, Z; Orbay, P; Simon, L; Szilágyi, G1

Reviews

1 review(s) available for selegiline and Brain Ischemia

ArticleYear
Environmental influence on recovery after brain lesions--experimental and clinical data.
    Journal of rehabilitation medicine, 2003, Issue:41 Suppl

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Dendrites; Environment; Humans; Motor Activity; Neuronal Plasticity; Neuroprotective Agents; Pyramidal Cells; Rats; Selegiline; Stem Cell Transplantation

2003

Other Studies

17 other study(ies) available for selegiline and Brain Ischemia

ArticleYear
Selegiline (L-Deprenyl) Mitigated Oxidative Stress, Cognitive Abnormalities, and Histopathological Change in Rats: Alternative Therapy in Transient Global Ischemia.
    Journal of molecular neuroscience : MN, 2020, Volume: 70, Issue:10

    Topics: Animals; Antioxidants; Brain; Brain Ischemia; Cognition; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Selegiline

2020
Possible involvement of PI3K/AKT/mTOR signaling pathway in the protective effect of selegiline (deprenyl) against memory impairment following ischemia reperfusion in rat.
    Neuropeptides, 2019, Volume: 77

    Topics: Animals; Brain Ischemia; Hippocampus; Male; Maze Learning; Memory; Memory Disorders; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Selegiline; Signal Transduction; TOR Serine-Threonine Kinases

2019
Effect of MAO-B inhibition against ischemia-induced oxidative stress in the rat brain. Comparison with a rational antioxidant.
    Arzneimittel-Forschung, 2008, Volume: 58, Issue:4

    Topics: Animals; Antioxidants; beta Carotene; Brain Chemistry; Brain Ischemia; Catalase; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Male; Malondialdehyde; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Selegiline; Superoxide Dismutase

2008
(-)Deprenyl-N-oxide, a (-)deprenyl metabolite, is cytoprotective after hypoxic injury in PC12 cells, or after transient brain ischemia in gerbils.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Animals; Apoptosis; Brain Ischemia; Carotid Artery Diseases; Cell Death; Cell Hypoxia; Gerbillinae; Hippocampus; Mitochondrial Membranes; Neurons; Neuroprotective Agents; PC12 Cells; Rats; Reactive Oxygen Species; Selegiline; Time Factors

2009
Cerebral ischemia-reperfusion induces GAPDH S-nitrosylation and nuclear translocation.
    Biochemistry. Biokhimiia, 2012, Volume: 77, Issue:6

    Topics: Active Transport, Cell Nucleus; Analysis of Variance; Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; Cell Nucleus; Dizocilpine Maleate; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Indazoles; Male; Monoamine Oxidase; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroso Compounds; Nuclear Proteins; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Selegiline; Ubiquitin-Protein Ligases; Vitamin B 12

2012
l-Deprenyl prevents lipid peroxidation and memory deficits produced by cerebral ischemia in rats.
    Cellular and molecular neurobiology, 2004, Volume: 24, Issue:1

    Topics: Animals; Antioxidants; Avoidance Learning; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Lipid Peroxidation; Maze Learning; Memory Disorders; Motor Activity; Neuroprotective Agents; Nitrites; Rats; Rats, Wistar; Selegiline; Thiobarbituric Acid Reactive Substances

2004
Selegiline potentiates the effects of EGb 761 in response to ischemic brain injury.
    Neurochemistry international, 2004, Volume: 45, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Drug Synergism; Gerbillinae; Ginkgo biloba; Male; Mice; Mice, Inbred BALB C; Motor Activity; Plant Extracts; Reactive Oxygen Species; Selegiline

2004
Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage.
    European journal of pharmacology, 1996, Nov-07, Volume: 315, Issue:1

    Topics: Animals; Animals, Newborn; Astrocytes; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Hippocampus; Immunohistochemistry; Male; Mice; Nerve Growth Factors; Neurons; Neuroprotective Agents; Rats; Rats, Inbred F344; RNA, Messenger; Selegiline

1996
L-Deprenyl does not reduce brain damage in global forebrain ischemia in adult gerbils (Meriones ungiculatus).
    Journal of the neurological sciences, 1997, May-01, Volume: 148, Issue:1

    Topics: Age Factors; Animals; Brain Ischemia; Cell Death; Gerbillinae; Neuroprotective Agents; Prosencephalon; Pyramidal Cells; Reperfusion Injury; Selegiline

1997
A cell culture model of cerebral ischemia as a convenient system to screen for neuroprotective drugs.
    Journal of neural transmission. Supplementum, 1998, Volume: 52

    Topics: Animals; Benzophenones; Brain Ischemia; Catechol O-Methyltransferase Inhibitors; Cell Survival; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; L-Lactate Dehydrogenase; Models, Neurological; Monoamine Oxidase Inhibitors; Neurons; Neuroprotective Agents; Nitrophenols; Prosencephalon; Rats; Rats, Sprague-Dawley; Selegiline; Time Factors; Tolcapone

1998
Cytoprotection by deprenyl and tolcapone in a cell culture model of cerebral ischaemia.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:5

    Topics: Animals; Benzophenones; Brain Ischemia; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Hypoxia; Cells, Cultured; Cytoprotection; Drug Combinations; Female; Hypoglycemia; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Nitrophenols; Pregnancy; Prosencephalon; Rats; Rats, Sprague-Dawley; Selegiline; Tolcapone

1998
Different neurorescue profiles of selegiline and p-fluoro-selegiline in gerbils.
    Neuroreport, 2000, Aug-03, Volume: 11, Issue:11

    Topics: Animals; Brain Ischemia; Cell Survival; Dose-Response Relationship, Drug; Fluorine Compounds; Gerbillinae; Hippocampus; Male; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Pyramidal Cells; Reperfusion Injury; Selegiline

2000
The neuroprotective effects of (-)deprenyl in the gerbil hippocampus following transient global ischemia.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:7

    Topics: Animals; Brain Ischemia; Cell Death; Female; Gerbillinae; Hippocampus; Monoamine Oxidase Inhibitors; Pyramidal Cells; Selegiline

2000
MAO-B inhibition by a single dose of l-deprenyl or lazabemide does not prevent neuronal damage following focal cerebral ischaemia in rats.
    Pharmacology & toxicology, 2000, Volume: 87, Issue:5

    Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Picolinic Acids; Rats; Rats, Wistar; Selegiline

2000
Selegiline combined with enriched-environment housing attenuates spatial learning deficits following focal cerebral ischemia in rats.
    Experimental neurology, 2001, Volume: 167, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; Disease Models, Animal; Drug Administration Schedule; Environment; Forelimb; Housing, Animal; Male; Maze Learning; Motor Activity; Rats; Rats, Wistar; Selegiline; Spatial Behavior

2001
Chronic daily administration of selegiline and EGb 761 increases brain's resistance to ischemia in mice.
    Brain research, 2001, Nov-02, Volume: 917, Issue:2

    Topics: Actins; Animals; Apoptosis; Brain; Brain Ischemia; Caspases; Cerebral Infarction; Drug Administration Schedule; Ginkgo biloba; Immunity, Innate; In Situ Nick-End Labeling; Mice; Neurons; Neuroprotective Agents; Plant Extracts; Selegiline

2001
(-)-D-Deprenyl attenuates apoptosis in experimental brain ischaemia.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Animals; Apoptosis; Brain Infarction; Brain Ischemia; Electrocoagulation; GAP-43 Protein; Gene Expression Regulation; In Situ Nick-End Labeling; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger; Selegiline; Temporal Lobe

2001