Page last updated: 2024-08-23

selegiline and Amyotrophic Lateral Sclerosis

selegiline has been researched along with Amyotrophic Lateral Sclerosis in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's10 (71.43)18.2507
2000's3 (21.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gourie-Devi, M; Harsha, HN; Nalini, A; Raju, TR; Rammohan, P; Shahani, N; Shobha, K1
Aquilonius, SM; Askmark, H; Blomquist, G; Engler, H; Johansson, A; Långström, B; Scott, B; Wall, A1
Zaleska, B1
Aquilonius, SM; Ekblom, J; Gudjonsson, O; Hagbarth, KE; Jossan, SS1
Aquilonius, SM; Ekblom, J; Jossan, SS; Oreland, L1
Aquilonius, SM; Ekblom, J; Jossan, SS; Oreland, L; Walum, E1
Balzarini, C; Mazzini, L; Mora, G; Testa, D1
Aquilonius, SM; Bergström, M; Ekblom, J; Jossan, SS; Oreland, L; Walum, E1
Kuhn, W; Müller, T1
Appel, SH; Appel, V; Diamond, B; Lai, EC; Lange, DJ; Murphy, PL; Younger, DS1
Maloteaux, JM1
Jamrozik, Z; Janik, P; Kwieciński, H; Opuchlik, A1
Aquilonius, SM; Askmark, H; Ekblom, JG; Gillberg, PG; Jossan, SS1
Aquilonius, SM; Ekblom, J; Gillberg, PG; Jossan, SS; Oreland, L1

Reviews

2 review(s) available for selegiline and Amyotrophic Lateral Sclerosis

ArticleYear
[Progress in the treatment of degenerative diseases of the nervous system. Selected problems].
    Neurologia i neurochirurgia polska, 1980, Volume: 14, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Antiparkinson Agents; Humans; Huntington Disease; Lithium; Neostigmine; Parkinson Disease; Penicillamine; Phthalazines; Selegiline; Tetrabenazine; Tiapamil Hydrochloride

1980
The clinical potential of Deprenyl in neurologic and psychiatric disorders.
    Journal of neural transmission. Supplementum, 1996, Volume: 48

    Topics: Adult; Aged; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Antipsychotic Agents; Child; Clinical Trials as Topic; Cross-Over Studies; Depression; Double-Blind Method; Humans; Mental Disorders; Middle Aged; Monoamine Oxidase Inhibitors; Narcolepsy; Nervous System Diseases; Neuroprotective Agents; Nootropic Agents; Parkinson Disease, Secondary; Schizophrenia; Selegiline; Supranuclear Palsy, Progressive; Tourette Syndrome; Treatment Outcome

1996

Trials

4 trial(s) available for selegiline and Amyotrophic Lateral Sclerosis

ArticleYear
Double blind cross over trial with deprenyl in amyotrophic lateral sclerosis.
    Journal of neural transmission. Supplementum, 1994, Volume: 41

    Topics: Amyotrophic Lateral Sclerosis; Blood Platelets; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nervous System; Selegiline; Treatment Outcome

1994
An open-randomized clinical trial of selegiline in amyotrophic lateral sclerosis.
    Journal of neurology, 1994, Volume: 241, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Female; Humans; Male; Middle Aged; Selegiline; Survival Rate; Treatment Outcome

1994
Selegiline is ineffective in a collaborative double-blind, placebo-controlled trial for treatment of amyotrophic lateral sclerosis.
    Archives of neurology, 1998, Volume: 55, Issue:1

    Topics: Administration, Oral; Amyotrophic Lateral Sclerosis; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Selegiline; Treatment Outcome

1998
[The effect of selegiline and vitamin E in the treatment of ALS: an open randomized clinical trials].
    Neurologia i neurochirurgia polska, 2001, Volume: 35, Issue:1 Suppl

    Topics: Adolescent; Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuroprotective Agents; Selegiline; Survival Rate; Vitamin E

2001

Other Studies

8 other study(ies) available for selegiline and Amyotrophic Lateral Sclerosis

ArticleYear
(-)-Deprenyl alleviates the degenerative changes induced in the neonatal rat spinal cord by CSF from amyotrophic lateral sclerosis patients.
    Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 2004, Volume: 5, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Case-Control Studies; Cell Count; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; L-Lactate Dehydrogenase; Neurofilament Proteins; Neuroprotective Agents; Phosphorylation; Rats; Rats, Wistar; Selegiline; Spinal Cord; Spinal Cord Diseases; Time Factors

2004
Evidence for astrocytosis in ALS demonstrated by [11C](L)-deprenyl-D2 PET.
    Journal of the neurological sciences, 2007, Apr-15, Volume: 255, Issue:1-2

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Astrocytes; Brain; Brain Mapping; Carbon Radioisotopes; Deuterium; Female; Gliosis; Humans; Male; Middle Aged; Monoamine Oxidase; Nerve Fibers, Myelinated; Positron-Emission Tomography; Predictive Value of Tests; Selegiline

2007
Monoamine oxidase-B in motor cortex and spinal cord in amyotrophic lateral sclerosis studied by quantitative autoradiography.
    Journal of neural transmission. Supplementum, 1994, Volume: 41

    Topics: Amyotrophic Lateral Sclerosis; Autoradiography; Humans; Monoamine Oxidase; Motor Cortex; Reference Values; Selegiline; Spinal Cord; Tissue Distribution

1994
Reactive gliosis and monoamine oxidase B.
    Journal of neural transmission. Supplementum, 1994, Volume: 41

    Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Autoradiography; Cadaver; Cells, Cultured; Gliosis; Humans; Immunohistochemistry; Monoamine Oxidase; Rats; Reference Values; Selegiline; Spinal Cord

1994
Monoamine oxidase-B in astrocytes.
    Glia, 1993, Volume: 8, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Astrocytes; Astrocytoma; Autoradiography; Biomarkers; Brain Neoplasms; Cells, Cultured; Cerebral Cortex; Emulsions; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Monoamine Oxidase; Neoplasm Proteins; Nerve Tissue Proteins; Rats; Selegiline; Spinal Cord

1993
[Clinical pharmacology and therapeutic aspects in certain degenerative neurological diseases].
    Bulletin et memoires de l'Academie royale de medecine de Belgique, 1996, Volume: 151, Issue:10-11

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antiparkinson Agents; Cholinesterase Inhibitors; Humans; Neuroprotective Agents; Parkinson Disease; Riluzole; Selegiline; Tacrine

1996
Increased binding of 3H-L-deprenyl in spinal cords from patients with amyotrophic lateral sclerosis as demonstrated by autoradiography.
    Journal of neural transmission. General section, 1992, Volume: 89, Issue:1-2

    Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Autoradiography; Female; Histocytochemistry; Humans; Male; Monoamine Oxidase; Motor Neurons; Neuroglia; Selegiline; Spinal Cord

1992
Monoamine oxidase-B in motor cortex: changes in amyotrophic lateral sclerosis.
    Neuroscience, 1992, Volume: 49, Issue:4

    Topics: Aged; Amyotrophic Lateral Sclerosis; Autoradiography; Brain; Cerebral Cortex; Female; Humans; Isoenzymes; Male; Middle Aged; Monoamine Oxidase; Selegiline; Tritium

1992