selamectin and Scabies

For a number of reasons, several of the more 'traditional' ectoparasiticides in the small animal veterinarian's armoury have been withdrawn over the past few years. New, safer products which are long-acting and easier to apply than the conventional dips, rinses and aerosol sprays of the past have replaced them. However, relatively few such novel acaricidal preparations have become commercially available. Consequently, practitioners and researchers frequently experiment with the drugs they have at their disposal to assess their efficacy against a variety of target acarids when used at different dosages and/or via different routes of administration, compared with those recommended by the manufacturer. This paper reviews the anecdotal and peer-reviewed reports describing the use of modern acaricides in dogs and cats that have recently appeared in the veterinary literature. It should be stressed, however, that no medicine should be prescribed for extra-label use without the informed consent of the owner.

Topics: Administration, Cutaneous; Administration, Oral; Animals; Cat Diseases; Cats; Clinical Trials as Topic; Dog Diseases; Dogs; Insecticides; Ivermectin; Macrolides; Mite Infestations; Mites; Pyrazoles; Scabies; Toluidines

Topics: Administration, Topical; Animals; Antiparasitic Agents; Dog Diseases; Dogs; Drug Therapy, Combination; Imidazoles; Insecticides; Ivermectin; Macrolides; Neonicotinoids; Nitro Compounds; Scabies; Treatment Outcome

Sarcoptes scabiei is a widespread, highly contagious skin disease that affects many mammals including humans. The biological characteristics of S. scabiei remain unclear. Therefore, the ability to collect adequate amount of mites for studies is required to advance our understanding of the parasite. The present study aimed to find a method to collect an adequate amount of live S. scabiei mites within a short time frame. The cornified layer and fur from an infected raccoon dog were inserted into a 50-ml catheter tip-type syringe. A 1.5-ml microtube was attached at the tip of the syringe to collect the mites, which crawled out from the cornified layer and fur. Four conditions were examined, and the following condition was determined to be the best: the syringe and microtube were shaded by aluminum foil, and the microtube was heated using a pet heater (36 °C). In addition, the effectiveness of this method as an alternative method to diagnose S. scabiei infections in animal was evaluated. S. scabiei live mites were not detected in the raccoon dog samples 24 h after the administration of medication (ivermectin or selamectin). The present study revealed that this technique was useful to collect adequate amounts of live mites, and the mites prefer a heated environment and actively move when using the shaded conditions. In addition, this technique was effective as an alternative diagnostic technique to detect live mites on an animal body.

Topics: Animals; Disease Models, Animal; Dogs; Humans; Ivermectin; Mammals; Raccoon Dogs; Sarcoptes scabiei; Scabies; Skin

Topics: Animals; Antiparasitic Agents; Dog Diseases; Dogs; Ivermectin; Male; Pruritus; Scabies; Treatment Outcome

Topics: Animals; Antiparasitic Agents; Cat Diseases; Cats; Humans; Ivermectin; Male; Scabies; Treatment Outcome; United Kingdom; Zoonoses

Topics: Animals; Antiparasitic Agents; Dog Diseases; Dogs; Ivermectin; Pruritus; Scabies

Topics: Administration, Cutaneous; Animals; Antiparasitic Agents; Ivermectin; Male; Rabbits; Sarcoptes scabiei; Scabies; Skin; Treatment Outcome

The authors report 10 cases of localised sarcoptic mange in dogs. In each case, lesions were localised to one precise area of the skin. Pruritus was present in nine cases and absent in one. Affected areas were the feet (one case), the face and/or the pinnae (six cases), the abdominal skin (one case), the flank (one case) and the lumbar area (one case). The types of lesions were erythema, papules, lichenification, scales, crusts and alopecia. Parasites were found in all cases except one, in which anti-immunoglobulin G Sarcoptes serology was positive. The acaricidal treatments given were lindane, ivermectin or selamectin and were all successful.

Topics: Alopecia; Animals; Dog Diseases; Dogs; Female; Hexachlorocyclohexane; Insecticides; Ivermectin; Male; Pruritus; Retrospective Studies; Sarcoptes scabiei; Scabies; Skin; Treatment Outcome