secobarbital has been researched along with Sleep Initiation and Maintenance Disorders in 28 studies
Secobarbital: A barbiturate that is used as a sedative. Secobarbital is reported to have no anti-anxiety activity.
secobarbital : A member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The hypnotic effects of l-tryptophan (1 g), secobarbital (100 mg), and flurazepam (30 mg), relative to placebo, were evaluated in a sample of 54 outpatient chronic insomniacs with a major complaint of sleep maintenance insomnia." | 5.05 | Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report. ( Hartmann, EL; Lindsley, JG; Mitchell, W, 1983) |
| "Triazolam 0." | 2.64 | A clinical comparison of triazolam with placebo and with secobarbital in insomniac patients. ( Allens, GS; Okawa, KK, 1978) |
| "Secobarbital, 100 mg, was evaluated in two separate sleep laboratory drug evaluation studies, each with 4 insomniac patients." | 2.64 | Effectiveness of intermediate-term use of secobarbital. ( Bixler, EO; Hauri, P; Kales, A; Silberfarb, P, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HINTON, JM | 2 |
| le RICHE, W | 1 |
| RICKELS, K | 2 |
| BASS, H | 1 |
| JONES, DP | 1 |
| JONES, EA | 1 |
| LHERMANN, J | 1 |
| Philipp, E | 1 |
| Kapp, W | 1 |
| Lindsley, JG | 2 |
| Hartmann, EL | 1 |
| Mitchell, W | 1 |
| Hartmann, E | 1 |
| Spinweber, C | 1 |
| Okawa, KK | 1 |
| Allens, GS | 1 |
| Kales, A | 3 |
| Hauri, P | 1 |
| Bixler, EO | 3 |
| Silberfarb, P | 1 |
| Gingrich, RL | 1 |
| Morris, RJ | 1 |
| Rosenfeld, H | 1 |
| Perloff, MM | 1 |
| Clark, EL | 1 |
| Schilling, A | 1 |
| Tan, TL | 2 |
| Scharf, MB | 1 |
| Kales, JD | 2 |
| White, RB | 1 |
| Gathman, LT | 1 |
| Pattison, JH | 1 |
| Allen, RP | 1 |
| Panaccio, L | 1 |
| Tétreault, L | 4 |
| Ananth, JV | 1 |
| Bronheim, LA | 1 |
| Klingner, A | 1 |
| Ban, TA | 1 |
| Huot, J | 1 |
| Bordeleau, JM | 3 |
| Bucher, HW | 1 |
| Soulairac, A | 1 |
| Johns, MW | 1 |
| Hepburn, M | 1 |
| Goodyear, MD | 1 |
| Cohen, S | 1 |
| Bloomfield, SS | 1 |
| Lareniere, B | 1 |
| Evans, DR | 1 |
| Bond, IK | 1 |
| Shapiro, S | 1 |
| Slone, D | 1 |
| Lewis, GP | 1 |
| Jick, H | 1 |
15 trials available for secobarbital and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Comparative study of midazolam and vesparax in moderate or severe insomnia in female surgical patients.
Topics: Adult; Aged; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Dreams; Drug Combinations; Female; | 1983 |
Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report.
Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Hypn | 1983 |
Chronic insomnia: effects of tryptophan, flurazepam, secobarbital, and placebo.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Male; Placebos; Secoba | 1983 |
A clinical comparison of triazolam with placebo and with secobarbital in insomniac patients.
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Mid | 1978 |
Effectiveness of intermediate-term use of secobarbital.
Topics: Adult; Clinical Trials as Topic; Drug Administration Schedule; Drug Tolerance; Electroencephalograph | 1976 |
Triazolam in insomniac family practice patients.
Topics: Benzodiazepines; Clinical Trials as Topic; Emotions; Family Practice; Female; Humans; Hypnotics and | 1975 |
Comparison of the hypnotic effectiveness of secobarbital, pentobarbital, methyprylon and ethchlorvynol.
Topics: Age Factors; Aged; Clinical Trials as Topic; Ethchlorvynol; Humans; Hypnotics and Sedatives; Pentoba | 1972 |
[Comparative study of the hypnotic properties of flurazepam (30 mg), secobarbital (100 mg) and placebos for 4 types of psychotic insomniacs].
Topics: Adult; Chlordiazepoxide; Clinical Trials as Topic; Female; Humans; Male; Methods; Middle Aged; Place | 1972 |
The effects of hypnotic drugs on performance.
Topics: Attention; Chloral Hydrate; Chlordiazepoxide; Cognition; Decision Making; Glutethimide; Humans; Hypn | 1973 |
Diazepam in the treatment of insomnia in psychiatric patients.
Topics: Adult; Chloral Hydrate; Clinical Trials as Topic; Diazepam; Female; Humans; Hypnotics and Sedatives; | 1973 |
[Evaluation of the hypnotic properties of nitrazepam (Mogadon) in insomnia in mental patients].
Topics: Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Placebos; | 1966 |
[Comparative evaluation of Mnadrax, secobarbital and placebo in the mental patient: Mandrax tolerance and Mandrax-secobarbital cross tolerance].
Topics: Adolescent; Adult; Analysis of Variance; Clinical Trials as Topic; Diphenhydramine; Drug Tolerance; | 1968 |
[Hypnotic action of mecloqualone. Comparison with placebo effects and secobarbital].
Topics: Adult; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Placebos; Quinazolines; Secoba | 1971 |
A double-blind clinical evaluation of a new non-barbiturate hypnotic-somnafac.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Male; Methaqualone; | 1965 |
A method for the evaluation of hypnotic agents in man. The comparative hypnotic effects of secobarbital, methaqualone and placebo in normal subjects and in psychiatric patients.
Topics: Adult; Clinical Trials as Topic; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Methaqualo | 1967 |
13 other studies available for secobarbital and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
The actions of amylobarbitone sodium, butobarbitone and quinalbarbitone sodium upon insomnia and nocturnal restlessness compared in psychiatric patients.
Topics: Adult; Amobarbital; Barbiturates; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male | 1961 |
A comparison of the effects of six barbiturates and a placebo on insomnia and motility in psychiatric patients.
Topics: Barbiturates; Double-Blind Method; Female; Hexobarbital; Humans; Hypnotics and Sedatives; Male; Midd | 1963 |
Clinical and statistical evaluation of six hypnotic agents.
Topics: Glutethimide; Humans; Hypnotics and Sedatives; Piperidones; Placebo Effect; Secobarbital; Sleep; Sle | 1963 |
A comparative controlled clinical trial of seven hypnotic agents in medical and psychiatric in-patients.
Topics: Chloral Hydrate; Glutethimide; Humans; Hypnotics and Sedatives; Meprobamate; Secobarbital; Sleep Ini | 1963 |
DRUGS FOR INSOMNIA.
Topics: Amobarbital; Child; Chloral Hydrate; Diphenhydramine; Humans; Paraldehyde; Phenobarbital; Promethazi | 1963 |
[CLINICAL APPLICATION OF A NEW VERY ACTIVE HYPNOTIC ASSOCIATING SODIUM SECOBARBITAL, CALCIUM BRALLOBARBITAL AND HYDROXYZINE (UC-8130)].
Topics: Barbiturates; Depression; Depressive Disorder; Geriatrics; Humans; Hydroxyzine; Hypnotics and Sedati | 1964 |
Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence.
Topics: Adult; Age Factors; Aged; Amobarbital; Chloral Hydrate; Chronic Disease; Dreams; Drug Therapy, Combi | 1974 |
The syndrome of ordinary grief.
Topics: Adjustment Disorders; Adolescent; Adult; Amitriptyline; Child; Crying; Death; Feeding and Eating Dis | 1973 |
[Combination of proscillaridin A and secobarbital. Clinical report].
Topics: Aged; Anxiety; Bufanolides; Drug Combinations; Female; Heart; Heart Diseases; Humans; Male; Secobarb | 1972 |
Use of hypnotic drugs by hospital patients.
Topics: Adult; Aged; Amobarbital; Antipyrine; Barbiturates; Diphenhydramine; Female; Hospitalization; Humans | 1971 |
Reciprocal inhibition therapy and classical conditioning in the treatment of insomnia.
Topics: Adult; Conditioning, Classical; Conditioning, Psychological; Humans; Male; Methohexital; Middle Aged | 1969 |
[Controlled clinical evaluation of a combination of barbiturates and hydroxyzine].
Topics: Barbiturates; Humans; Hydroxyzine; Secobarbital; Sleep Initiation and Maintenance Disorders | 1967 |
Clinical effects of hypnotics. II. An epidemiologic study.
Topics: Body Weight; Chloral Hydrate; Diphenhydramine; Female; Humans; Hypnotics and Sedatives; Male; Pentob | 1969 |