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secobarbital and Muscle Contraction

secobarbital has been researched along with Muscle Contraction in 5 studies

Secobarbital: A barbiturate that is used as a sedative. Secobarbital is reported to have no anti-anxiety activity.
secobarbital : A member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Fatigue was accelerated by SCB for both muscle types."1.26Fast and slow skeletal muscles: effect of secobarbital on contractility of muscles from mice. ( Abresch, RT; Fowler, WM; Lieberman, JS; Taylor, RG, 1980)
"Using isolated rat aortic strips (AS) and portal veins (PV), it was found that all of the barbiturates studied (thiopental, secobarbital, pentobarbital, amobarbital, phenobarbital, and barbital): a) inhibit development of spontaneous mechanical activity (vasomotion) in AS and PV in concentrations used to induce surgical anesthesia or concentrations used for anticonvulsive therapy; b) dose-dependent attenuate contractions induced by epinephrine and potassium (K+); c) cause non-competitive displacement of the dose-response curves of these vasoactive compounds; d) attenuate calcium (Ca++)-induced contractions of K+-depolarized AS and PV; e) rapidly relax drug-induced, as well as Ca++-induced, contractions of AS and PV."1.25Barbiturates and aortic and venous smooth-muscle function. ( Altura, BM; Altura, BT, 1975)
"In a patient with reflex myoclonus limited to the right side of the body, stimulation of the right median nerve in the index finger or wrist elicited a very large somatosensory evoked response (SER) and a long loop C reflex which represents an electrically evoked myoclonic response."1.25Focal reflex myoclonus. ( Mayer, RF; Sutton, GG, 1974)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taylor, RG1
Abresch, RT1
Lieberman, JS1
Fowler, WM1
Altura, BT1
Altura, BM1
Darnell, RJ1
McCloskey, TC1
Commissaris, RL1
Luchi, RJ1
Kritcher, EM1
Sutton, GG1
Mayer, RF1

Other Studies

5 other studies available for secobarbital and Muscle Contraction

ArticleYear
Fast and slow skeletal muscles: effect of secobarbital on contractility of muscles from mice.
    Archives of physical medicine and rehabilitation, 1980, Volume: 61, Issue:4

    Topics: Animals; Body Weight; Electric Stimulation; Fatigue; Female; Hindlimb; Mice; Mice, Inbred Strains; M

1980
Barbiturates and aortic and venous smooth-muscle function.
    Anesthesiology, 1975, Volume: 43, Issue:4

    Topics: Amobarbital; Animals; Aorta, Thoracic; Barbiturates; Calcium; Depression, Chemical; Dose-Response Re

1975
Convulsant versus typical barbiturates: effects on locomotor activity.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Animals; Anticonvulsants; Barbiturates; Convulsants; Male; Motor Activity; Muscle Contraction; Rats;

1986
Drug effects on cardiac myosin adenosine triphosphatase activity.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Angiotensin II; Animals; Binding Sites; Calcium;

1967
Focal reflex myoclonus.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:2

    Topics: Aged; Cerebrovascular Disorders; Diazepam; Electric Stimulation; Electroencephalography; Evoked Pote

1974