secobarbital and Chronic Insomnia studies

secobarbital and Chronic Insomnia

secobarbital has been researched along with Chronic Insomnia in 28 studies

Secobarbital: A barbiturate that is used as a sedative. Secobarbital is reported to have no anti-anxiety activity.
secobarbital : A member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups.

Research Excerpts

Excerpt	Relevance	Reference
"The hypnotic effects of l-tryptophan (1 g), secobarbital (100 mg), and flurazepam (30 mg), relative to placebo, were evaluated in a sample of 54 outpatient chronic insomniacs with a major complaint of sleep maintenance insomnia."	5.05	Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report. ( Hartmann, EL; Lindsley, JG; Mitchell, W, 1983)
"Triazolam 0."	2.64	A clinical comparison of triazolam with placebo and with secobarbital in insomniac patients. ( Allens, GS; Okawa, KK, 1978)
"Secobarbital, 100 mg, was evaluated in two separate sleep laboratory drug evaluation studies, each with 4 insomniac patients."	2.64	Effectiveness of intermediate-term use of secobarbital. ( Bixler, EO; Hauri, P; Kales, A; Silberfarb, P, 1976)

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

28 (100.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
HINTON, JM	2
le RICHE, W	1
RICKELS, K	2
BASS, H	1
JONES, DP	1
JONES, EA	1
LHERMANN, J	1
Philipp, E	1
Kapp, W	1
Lindsley, JG	2
Hartmann, EL	1
Mitchell, W	1
Hartmann, E	1
Spinweber, C	1
Okawa, KK	1
Allens, GS	1
Kales, A	3
Hauri, P	1
Bixler, EO	3
Silberfarb, P	1
Gingrich, RL	1
Morris, RJ	1
Rosenfeld, H	1
Perloff, MM	1
Clark, EL	1
Schilling, A	1
Tan, TL	2
Scharf, MB	1
Kales, JD	2
White, RB	1
Gathman, LT	1
Pattison, JH	1
Allen, RP	1
Panaccio, L	1
Tétreault, L	4
Ananth, JV	1
Bronheim, LA	1
Klingner, A	1
Ban, TA	1
Huot, J	1
Bordeleau, JM	3
Bucher, HW	1
Soulairac, A	1
Johns, MW	1
Hepburn, M	1
Goodyear, MD	1
Cohen, S	1
Bloomfield, SS	1
Lareniere, B	1
Evans, DR	1
Bond, IK	1
Shapiro, S	1
Slone, D	1
Lewis, GP	1
Jick, H	1

Studies

HINTON, JM

le RICHE, W

RICKELS, K

BASS, H

JONES, DP

JONES, EA

LHERMANN, J

Philipp, E

Kapp, W

Lindsley, JG

Hartmann, EL

Mitchell, W

Hartmann, E

Spinweber, C

Okawa, KK

Allens, GS

Kales, A

Hauri, P

Bixler, EO

Silberfarb, P

Gingrich, RL

Morris, RJ

Rosenfeld, H

Perloff, MM

Clark, EL

Schilling, A

Tan, TL

Scharf, MB

Kales, JD

White, RB

Gathman, LT

Pattison, JH

Allen, RP

Panaccio, L

Tétreault, L

Ananth, JV

Bronheim, LA

Klingner, A

Ban, TA

Huot, J

Bordeleau, JM

Bucher, HW

Soulairac, A

Johns, MW

Hepburn, M

Goodyear, MD

Cohen, S

Bloomfield, SS

Lareniere, B

Evans, DR

Bond, IK

Shapiro, S

Slone, D

Lewis, GP

Jick, H

Trials

15 trials available for secobarbital and Chronic Insomnia

Article	Year
Comparative study of midazolam and vesparax in moderate or severe insomnia in female surgical patients. British journal of clinical pharmacology, 1983, Volume: 16 Suppl 1 Topics: Adult; Aged; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Dreams; Drug Combinations; Female;	1983
Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report. Sleep, 1983, Volume: 6, Issue:3 Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Hypn	1983
Chronic insomnia: effects of tryptophan, flurazepam, secobarbital, and placebo. Psychopharmacology, 1983, Volume: 80, Issue:2 Topics: Adult; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Male; Placebos; Secoba	1983
A clinical comparison of triazolam with placebo and with secobarbital in insomniac patients. The Journal of international medical research, 1978, Volume: 6, Issue:4 Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Mid	1978
Effectiveness of intermediate-term use of secobarbital. Clinical pharmacology and therapeutics, 1976, Volume: 20, Issue:5 Topics: Adult; Clinical Trials as Topic; Drug Administration Schedule; Drug Tolerance; Electroencephalograph	1976
Triazolam in insomniac family practice patients. Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:3 Topics: Benzodiazepines; Clinical Trials as Topic; Emotions; Family Practice; Female; Humans; Hypnotics and	1975
Comparison of the hypnotic effectiveness of secobarbital, pentobarbital, methyprylon and ethchlorvynol. Journal of the American Geriatrics Society, 1972, Volume: 20, Issue:8 Topics: Age Factors; Aged; Clinical Trials as Topic; Ethchlorvynol; Humans; Hypnotics and Sedatives; Pentoba	1972
[Comparative study of the hypnotic properties of flurazepam (30 mg), secobarbital (100 mg) and placebos for 4 types of psychotic insomniacs]. L'union medicale du Canada, 1972, Volume: 101, Issue:11 Topics: Adult; Chlordiazepoxide; Clinical Trials as Topic; Female; Humans; Male; Methods; Middle Aged; Place	1972
The effects of hypnotic drugs on performance. Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:1 Topics: Attention; Chloral Hydrate; Chlordiazepoxide; Cognition; Decision Making; Glutethimide; Humans; Hypn	1973
Diazepam in the treatment of insomnia in psychiatric patients. Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:4 Topics: Adult; Chloral Hydrate; Clinical Trials as Topic; Diazepam; Female; Humans; Hypnotics and Sedatives;	1973
[Evaluation of the hypnotic properties of nitrazepam (Mogadon) in insomnia in mental patients]. L'union medicale du Canada, 1966, Volume: 95, Issue:12 Topics: Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Placebos;	1966
[Comparative evaluation of Mnadrax, secobarbital and placebo in the mental patient: Mandrax tolerance and Mandrax-secobarbital cross tolerance]. Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1968, Volume: 1, Issue:5 Topics: Adolescent; Adult; Analysis of Variance; Clinical Trials as Topic; Diphenhydramine; Drug Tolerance;	1968
[Hypnotic action of mecloqualone. Comparison with placebo effects and secobarbital]. La Presse medicale, 1971, Apr-10, Volume: 79, Issue:18 Topics: Adult; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Placebos; Quinazolines; Secoba	1971
A double-blind clinical evaluation of a new non-barbiturate hypnotic-somnafac. Western medicine; the medical journal of the west, 1965, Volume: 6, Issue:10 Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Male; Methaqualone;	1965
A method for the evaluation of hypnotic agents in man. The comparative hypnotic effects of secobarbital, methaqualone and placebo in normal subjects and in psychiatric patients. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:2 Topics: Adult; Clinical Trials as Topic; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Methaqualo	1967

Article

Year

Comparative study of midazolam and vesparax in moderate or severe insomnia in female surgical patients.

British journal of clinical pharmacology, 1983, Volume: 16 Suppl 1

Topics: Adult; Aged; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Dreams; Drug Combinations; Female;

1983

Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report.

Sleep, 1983, Volume: 6, Issue:3

Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Hypn

1983

Chronic insomnia: effects of tryptophan, flurazepam, secobarbital, and placebo.

Psychopharmacology, 1983, Volume: 80, Issue:2

Topics: Adult; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Male; Placebos; Secoba

1983

A clinical comparison of triazolam with placebo and with secobarbital in insomniac patients.

The Journal of international medical research, 1978, Volume: 6, Issue:4

Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Mid

1978

Effectiveness of intermediate-term use of secobarbital.

Clinical pharmacology and therapeutics, 1976, Volume: 20, Issue:5

Topics: Adult; Clinical Trials as Topic; Drug Administration Schedule; Drug Tolerance; Electroencephalograph

1976

Triazolam in insomniac family practice patients.

Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:3

Topics: Benzodiazepines; Clinical Trials as Topic; Emotions; Family Practice; Female; Humans; Hypnotics and

1975

Comparison of the hypnotic effectiveness of secobarbital, pentobarbital, methyprylon and ethchlorvynol.

Journal of the American Geriatrics Society, 1972, Volume: 20, Issue:8

Topics: Age Factors; Aged; Clinical Trials as Topic; Ethchlorvynol; Humans; Hypnotics and Sedatives; Pentoba

1972

[Comparative study of the hypnotic properties of flurazepam (30 mg), secobarbital (100 mg) and placebos for 4 types of psychotic insomniacs].

L'union medicale du Canada, 1972, Volume: 101, Issue:11

Topics: Adult; Chlordiazepoxide; Clinical Trials as Topic; Female; Humans; Male; Methods; Middle Aged; Place

1972

The effects of hypnotic drugs on performance.

Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:1

Topics: Attention; Chloral Hydrate; Chlordiazepoxide; Cognition; Decision Making; Glutethimide; Humans; Hypn

1973

Diazepam in the treatment of insomnia in psychiatric patients.

Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:4

Topics: Adult; Chloral Hydrate; Clinical Trials as Topic; Diazepam; Female; Humans; Hypnotics and Sedatives;

1973

[Evaluation of the hypnotic properties of nitrazepam (Mogadon) in insomnia in mental patients].

L'union medicale du Canada, 1966, Volume: 95, Issue:12

Topics: Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Placebos;

1966

[Comparative evaluation of Mnadrax, secobarbital and placebo in the mental patient: Mandrax tolerance and Mandrax-secobarbital cross tolerance].

Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1968, Volume: 1, Issue:5

Topics: Adolescent; Adult; Analysis of Variance; Clinical Trials as Topic; Diphenhydramine; Drug Tolerance;

1968

[Hypnotic action of mecloqualone. Comparison with placebo effects and secobarbital].

La Presse medicale, 1971, Apr-10, Volume: 79, Issue:18

Topics: Adult; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Placebos; Quinazolines; Secoba

1971

A double-blind clinical evaluation of a new non-barbiturate hypnotic-somnafac.

Western medicine; the medical journal of the west, 1965, Volume: 6, Issue:10

Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Male; Methaqualone;

1965

A method for the evaluation of hypnotic agents in man. The comparative hypnotic effects of secobarbital, methaqualone and placebo in normal subjects and in psychiatric patients.

The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:2

Topics: Adult; Clinical Trials as Topic; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Methaqualo

1967

Other Studies

13 other studies available for secobarbital and Chronic Insomnia

Article	Year
The actions of amylobarbitone sodium, butobarbitone and quinalbarbitone sodium upon insomnia and nocturnal restlessness compared in psychiatric patients. British journal of pharmacology and chemotherapy, 1961, Volume: 16 Topics: Adult; Amobarbital; Barbiturates; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male	1961
A comparison of the effects of six barbiturates and a placebo on insomnia and motility in psychiatric patients. British journal of pharmacology and chemotherapy, 1963, Volume: 20 Topics: Barbiturates; Double-Blind Method; Female; Hexobarbital; Humans; Hypnotics and Sedatives; Male; Midd	1963
Clinical and statistical evaluation of six hypnotic agents. Canadian Medical Association journal, 1963, Apr-20, Volume: 88 Topics: Glutethimide; Humans; Hypnotics and Sedatives; Piperidones; Placebo Effect; Secobarbital; Sleep; Sle	1963
A comparative controlled clinical trial of seven hypnotic agents in medical and psychiatric in-patients. The American journal of the medical sciences, 1963, Volume: 245 Topics: Chloral Hydrate; Glutethimide; Humans; Hypnotics and Sedatives; Meprobamate; Secobarbital; Sleep Ini	1963
DRUGS FOR INSOMNIA. Canadian Medical Association journal, 1963, Dec-28, Volume: 89 Topics: Amobarbital; Child; Chloral Hydrate; Diphenhydramine; Humans; Paraldehyde; Phenobarbital; Promethazi	1963
[CLINICAL APPLICATION OF A NEW VERY ACTIVE HYPNOTIC ASSOCIATING SODIUM SECOBARBITAL, CALCIUM BRALLOBARBITAL AND HYDROXYZINE (UC-8130)]. Gazette medicale de France, 1964, Mar-10, Volume: 71 Topics: Barbiturates; Depression; Depressive Disorder; Geriatrics; Humans; Hydroxyzine; Hypnotics and Sedati	1964
Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence. JAMA, 1974, Feb-04, Volume: 227, Issue:5 Topics: Adult; Age Factors; Aged; Amobarbital; Chloral Hydrate; Chronic Disease; Dreams; Drug Therapy, Combi	1974
The syndrome of ordinary grief. American family physician, 1973, Volume: 8, Issue:2 Topics: Adjustment Disorders; Adolescent; Adult; Amitriptyline; Child; Crying; Death; Feeding and Eating Dis	1973
[Combination of proscillaridin A and secobarbital. Clinical report]. Minerva medica, 1972, May-09, Volume: 63, Issue:35 Topics: Aged; Anxiety; Bufanolides; Drug Combinations; Female; Heart; Heart Diseases; Humans; Male; Secobarb	1972
Use of hypnotic drugs by hospital patients. The Medical journal of Australia, 1971, Dec-25, Volume: 2, Issue:26 Topics: Adult; Aged; Amobarbital; Antipyrine; Barbiturates; Diphenhydramine; Female; Hospitalization; Humans	1971
Reciprocal inhibition therapy and classical conditioning in the treatment of insomnia. Behaviour research and therapy, 1969, Volume: 7, Issue:3 Topics: Adult; Conditioning, Classical; Conditioning, Psychological; Humans; Male; Methohexital; Middle Aged	1969
[Controlled clinical evaluation of a combination of barbiturates and hydroxyzine]. Acta anaesthesiologica Belgica, 1967, Volume: 18, Issue:2 Topics: Barbiturates; Humans; Hydroxyzine; Secobarbital; Sleep Initiation and Maintenance Disorders	1967
Clinical effects of hypnotics. II. An epidemiologic study. JAMA, 1969, Sep-29, Volume: 209, Issue:13 Topics: Body Weight; Chloral Hydrate; Diphenhydramine; Female; Humans; Hypnotics and Sedatives; Male; Pentob	1969

Article

Year

The actions of amylobarbitone sodium, butobarbitone and quinalbarbitone sodium upon insomnia and nocturnal restlessness compared in psychiatric patients.

British journal of pharmacology and chemotherapy, 1961, Volume: 16

Topics: Adult; Amobarbital; Barbiturates; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male

1961

A comparison of the effects of six barbiturates and a placebo on insomnia and motility in psychiatric patients.

British journal of pharmacology and chemotherapy, 1963, Volume: 20

Topics: Barbiturates; Double-Blind Method; Female; Hexobarbital; Humans; Hypnotics and Sedatives; Male; Midd

1963

Clinical and statistical evaluation of six hypnotic agents.

Canadian Medical Association journal, 1963, Apr-20, Volume: 88

Topics: Glutethimide; Humans; Hypnotics and Sedatives; Piperidones; Placebo Effect; Secobarbital; Sleep; Sle

1963

A comparative controlled clinical trial of seven hypnotic agents in medical and psychiatric in-patients.

The American journal of the medical sciences, 1963, Volume: 245

Topics: Chloral Hydrate; Glutethimide; Humans; Hypnotics and Sedatives; Meprobamate; Secobarbital; Sleep Ini

1963

DRUGS FOR INSOMNIA.

Canadian Medical Association journal, 1963, Dec-28, Volume: 89

Topics: Amobarbital; Child; Chloral Hydrate; Diphenhydramine; Humans; Paraldehyde; Phenobarbital; Promethazi

1963

[CLINICAL APPLICATION OF A NEW VERY ACTIVE HYPNOTIC ASSOCIATING SODIUM SECOBARBITAL, CALCIUM BRALLOBARBITAL AND HYDROXYZINE (UC-8130)].

Gazette medicale de France, 1964, Mar-10, Volume: 71

Topics: Barbiturates; Depression; Depressive Disorder; Geriatrics; Humans; Hydroxyzine; Hypnotics and Sedati

1964

Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence.

JAMA, 1974, Feb-04, Volume: 227, Issue:5

Topics: Adult; Age Factors; Aged; Amobarbital; Chloral Hydrate; Chronic Disease; Dreams; Drug Therapy, Combi

1974

The syndrome of ordinary grief.

American family physician, 1973, Volume: 8, Issue:2

Topics: Adjustment Disorders; Adolescent; Adult; Amitriptyline; Child; Crying; Death; Feeding and Eating Dis

1973

[Combination of proscillaridin A and secobarbital. Clinical report].

Minerva medica, 1972, May-09, Volume: 63, Issue:35

Topics: Aged; Anxiety; Bufanolides; Drug Combinations; Female; Heart; Heart Diseases; Humans; Male; Secobarb

1972

Use of hypnotic drugs by hospital patients.

The Medical journal of Australia, 1971, Dec-25, Volume: 2, Issue:26

Topics: Adult; Aged; Amobarbital; Antipyrine; Barbiturates; Diphenhydramine; Female; Hospitalization; Humans

1971

Reciprocal inhibition therapy and classical conditioning in the treatment of insomnia.

Behaviour research and therapy, 1969, Volume: 7, Issue:3

Topics: Adult; Conditioning, Classical; Conditioning, Psychological; Humans; Male; Methohexital; Middle Aged

1969

[Controlled clinical evaluation of a combination of barbiturates and hydroxyzine].

Acta anaesthesiologica Belgica, 1967, Volume: 18, Issue:2

Topics: Barbiturates; Humans; Hydroxyzine; Secobarbital; Sleep Initiation and Maintenance Disorders

1967

Clinical effects of hypnotics. II. An epidemiologic study.

JAMA, 1969, Sep-29, Volume: 209, Issue:13

Topics: Body Weight; Chloral Hydrate; Diphenhydramine; Female; Humans; Hypnotics and Sedatives; Male; Pentob

1969