secobarbital has been researched along with Chemical Dependence in 49 studies
Secobarbital: A barbiturate that is used as a sedative. Secobarbital is reported to have no anti-anxiety activity.
secobarbital : A member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sertraline is an effective antidepressant acting as a selective serotonin reuptake inhibitor." | 2.68 | Comparative abuse liability of sertraline, alprazolam, and dextroamphetamine in humans. ( Busto, U; Kaplan, HL; Sellers, EM; Zawertailo, LA, 1995) |
| "Lorazepam was liked better than were other drugs only at 1 hour and only compared with buspirone 20 and placebo." | 2.67 | Comparative drug effects and abuse liability of lorazepam, buspirone, and secobarbital in nondependent subjects. ( Kaplan, HL; Romach, MK; Schneiderman, JF; Sellers, EM; Somer, GR, 1992) |
| "Experienced polydrug abusers (N = 190) were asked to indicate previous drugs used as well as drug preferences." | 1.26 | Indicated preference for drugs of abuse. ( Kliner, DJ; Pickens, R, 1982) |
| "Patients from a polydrug abuse treatment program were titrated with either secobarbital or methaqualone, their primary drug of abuse, to a state of mild intoxication, consisting of lateral and vertical nystagmus, ataxia, slurred speech, and drownsiness." | 1.26 | Dose-response studies on tolerance to multiple doses of secobarbital and methaqualone in a polydrug abuse population. ( Comstock, EG; Faulkner, TP; Hayden, JH; Mehta, CM; Olson, DA, 1979) |
| " Dose-response differences were also revealed in "breaking point" comparisons between secobarbital on the one hand, and methylphenidate and cocaine, on the other." | 1.26 | Behavioral procedures for evaluating the relative abuse potential of CNS drugs in primates. ( Brady, JV; Griffiths, RR, 1976) |
| "The occurrence of convulsions, during periods of complete reduction of the maintenance drug, became less frequent the longer the dogs had been maintained on a constant dose of sodium pentobarbital." | 1.26 | A method for bioassay of physical dependence on sedative drugs in dog. ( Jones, BE; Martin, WR; Prada, JA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (93.88) | 18.7374 |
| 1990's | 3 (6.12) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FRASER, HF | 1 |
| WIKLER, A | 2 |
| ESSIG, CF | 1 |
| ISBELL, H | 1 |
| Aderjan, R | 1 |
| Barz, J | 1 |
| Bösche, J | 1 |
| Mattern, R | 1 |
| Schmidt, G | 1 |
| Rumbaugh, CL | 1 |
| Fang, HC | 1 |
| Wilson, GH | 1 |
| Higgins, RE | 1 |
| Mestek, MF | 1 |
| Kliner, DJ | 1 |
| Pickens, R | 2 |
| Dymock, RB | 1 |
| James, RA | 1 |
| Lokan, RJ | 1 |
| Zawertailo, LA | 1 |
| Busto, U | 1 |
| Kaplan, HL | 2 |
| Sellers, EM | 2 |
| Faulkner, TP | 3 |
| Hayden, JH | 3 |
| Mehta, CM | 1 |
| Olson, DA | 2 |
| Comstock, EG | 3 |
| McGinity, JW | 2 |
| Martinez, M | 1 |
| Cleeland, R | 1 |
| Christenson, J | 1 |
| Usategui-Gomez, M | 1 |
| Heveran, J | 1 |
| Davis, R | 1 |
| Grunberg, E | 1 |
| Brady, JV | 1 |
| Griffiths, RR | 1 |
| Evanski, PM | 1 |
| Waugh, TR | 2 |
| Jones, BE | 1 |
| Prada, JA | 1 |
| Martin, WR | 1 |
| Gottheil, E | 1 |
| Caddy, GR | 1 |
| Austin, DL | 1 |
| Thompson, T | 1 |
| Roerig, DL | 1 |
| Lewand, DL | 1 |
| Mueller, MA | 1 |
| Wang, RI | 1 |
| Schneiderman, JF | 1 |
| Romach, MK | 1 |
| Somer, GR | 1 |
| McCaul, ME | 1 |
| Turkkan, JS | 1 |
| Svikis, DS | 1 |
| Bigelow, GE | 1 |
| Cwinn, AA | 1 |
| Marx, JA | 1 |
| Lox, CD | 1 |
| Lox, DM | 1 |
| Heine, MW | 1 |
| Kales, A | 1 |
| Bixler, EO | 1 |
| Tan, TL | 1 |
| Scharf, MB | 1 |
| Kales, JD | 1 |
| Tinklenberg, JR | 3 |
| Kopell, BS | 2 |
| Roth, WT | 2 |
| Darley, C | 1 |
| Woodrow, KM | 1 |
| Lamb, D | 1 |
| Roberts, G | 1 |
| Bleyer, WA | 1 |
| Marshall, RE | 1 |
| Frings, CS | 1 |
| Queen, CA | 1 |
| Schreiber, SN | 1 |
| Liebowitz, MR | 1 |
| Bernstein, LH | 1 |
| Findley, JD | 1 |
| Robinson, WW | 1 |
| Peregrino, L | 1 |
| Dolich, BH | 1 |
| Aiache, AE | 1 |
| Lloyd, WK | 1 |
| Porter, JM | 1 |
| Lindell, TD | 1 |
| Rösch, J | 1 |
| Dotter, CT | 1 |
| Daniel, DM | 1 |
| Choulis, NH | 1 |
| Maronde, RF | 1 |
| Silverman, M | 1 |
| Pugliese, AC | 1 |
| Kullberg, MP | 1 |
| Gorodetzky, CW | 1 |
| Walberg, CB | 1 |
| Murphy, PL | 1 |
| Murphy, P | 1 |
| Darley, CF | 1 |
| Gray, GR | 1 |
| Smith, DE | 2 |
| Wesson, DR | 2 |
| Sheppard, CW | 1 |
| Gaspar, MR | 1 |
| Hare, RR | 1 |
| Finkle, BS | 1 |
| Johns, MW | 1 |
| Hepburn, M | 1 |
| Goodyear, MD | 1 |
| Little, RB | 1 |
| Hadden, J | 1 |
| Johnson, K | 1 |
| Smith, S | 1 |
| Price, L | 1 |
| Giardina, E | 1 |
| Morgan, NR | 1 |
| Boback, MD | 1 |
| Kleckner, MS | 1 |
| Hamburger, E | 1 |
| Albo, D | 1 |
| Cheung, L | 1 |
| Ruth, L | 1 |
| Snyder, C | 1 |
| Reemtsma, K | 1 |
| Puro, HE | 1 |
| Wolf, PL | 1 |
| Skirgaudas, J | 1 |
| Vazquez, J | 1 |
2 reviews available for secobarbital and Chemical Dependence
| Article | Year |
|---|---|
Detection of drugs of abuse by radioimmunoassay: a summary of published data and some new information.
Topics: Amphetamine; Barbiturates; Cross Reactions; Drug Stability; Glutethimide; Humans; Methadone; Methaqu | 1976 |
An experimental analysis of behavioral factors in drug dependence.
Topics: Administration, Oral; Alcoholism; Amphetamine; Animals; Behavior, Animal; Cannabis; Chlorpromazine; | 1975 |
2 trials available for secobarbital and Chemical Dependence
| Article | Year |
|---|---|
Comparative abuse liability of sertraline, alprazolam, and dextroamphetamine in humans.
Topics: 1-Naphthylamine; Adolescent; Adult; Alprazolam; Arousal; Attention; Attitude; Dextroamphetamine; Dou | 1995 |
Comparative drug effects and abuse liability of lorazepam, buspirone, and secobarbital in nondependent subjects.
Topics: Adult; Affect; Attention; Buspirone; Dose-Response Relationship, Drug; Humans; Lorazepam; Male; Ment | 1992 |
45 other studies available for secobarbital and Chemical Dependence
| Article | Year |
|---|---|
Degree of physical dependence induced by secobarbital or pentobarbital.
Topics: Barbiturates; Behavior, Addictive; Humans; Pentobarbital; Secobarbital; Substance-Related Disorders | 1958 |
[Medical malpractice in the poisoning of drug addicts with Vesparax].
Topics: Adult; Barbiturates; Drug Combinations; Drug Prescriptions; Female; Humans; Hydroxyzine; Jurispruden | 1983 |
Cerebral CT findings in drug abuse: clinical and experimental observations.
Topics: Administration, Oral; Adolescent; Adult; Animals; Atrophy; Brain; Cannabis; Cerebral Ventricles; Dil | 1980 |
Indicated preference for drugs of abuse.
Topics: Adolescent; Adult; Amphetamines; Cannabis; Cocaine; Codeine; Diazepam; Ethanol; Female; Heroin; Huma | 1982 |
Tuinal as a drug of abuse.
Topics: Adolescent; Adult; Amobarbital; Drug Combinations; Female; Humans; Male; Secobarbital; Substance-Rel | 1980 |
Dose-response studies on tolerance to multiple doses of secobarbital and methaqualone in a polydrug abuse population.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Male; Methaqual | 1979 |
Pharmacokinetic studies on tolerance to multiple doses of sedative--hypnotics in a polydrug abuse population. II. Secobarbital--amobarbital.
Topics: Adult; Amobarbital; Drug Tolerance; Half-Life; Humans; Kinetics; Secobarbital; Substance-Related Dis | 1979 |
Pharmacokinetic studies on tolerance to sedative-hypnotics in a poly-drug abuse population. I Secobarbital.
Topics: Adolescent; Adult; Drug Tolerance; Female; Humans; Kinetics; Male; Models, Biological; Secobarbital; | 1978 |
Behavioral procedures for evaluating the relative abuse potential of CNS drugs in primates.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Haplorhini; Humans; Methylphenidate; Papio; Rein | 1976 |
Gluteal compartment syndrome: case report.
Topics: Adult; Buttocks; Humans; Male; Muscular Diseases; Sciatic Nerve; Secobarbital; Substance-Related Dis | 1977 |
A method for bioassay of physical dependence on sedative drugs in dog.
Topics: Animals; Dogs; Drug Evaluation, Preclinical; Humans; Hypnotics and Sedatives; Methaqualone; Pentobar | 1976 |
Fallibility of urine drug screens in monitoring methadone programs.
Topics: Amphetamine; Cocaine; Heroin Dependence; Humans; Laboratories; Licensure; Methadone; Morphine; Pharm | 1976 |
Comparison of radioimmunoassay with thin-layer chromatographic and gas-liquid chromatographic methods of barbiturate detection in human urine.
Topics: Adult; Amobarbital; Barbiturates; Chromatography, Gas; Chromatography, Thin Layer; Evaluation Studie | 1975 |
Alcohol and secobarbital effects as a function of familial alcoholism: acute psychophysiological effects.
Topics: Adult; Alcohol Drinking; Alcoholism; Arousal; Attention; Dose-Response Relationship, Drug; Humans; M | 1990 |
"Aural" intoxicants.
Topics: Adult; Amobarbital; Drug Combinations; Ear Canal; Humans; Male; Secobarbital; Substance-Related Diso | 1985 |
Effects of acute ethanol intoxication combined with secobarbital abuse on hemostasis.
Topics: Alcoholic Intoxication; Animals; Blood Coagulation Tests; Ethanol; Hemostasis; Male; Rats; Rats, Inb | 1985 |
Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence.
Topics: Adult; Age Factors; Aged; Amobarbital; Chloral Hydrate; Chronic Disease; Dreams; Drug Therapy, Combi | 1974 |
Proceedings: Drugs, delinquency, and aggression.
Topics: Adolescent; Aggression; Cannabis; Ethanol; Humans; Juvenile Delinquency; Male; Secobarbital; Substan | 1974 |
Drug use among youthful assaultive and sexual offenders.
Topics: Adolescent; Adult; Aggression; Alcoholism; Amphetamine; Barbiturates; California; Cannabis; Cocaine; | 1974 |
Starch and talc emboli in drug addicts' lungs.
Topics: Acetaminophen; Adult; Alcohols; Amobarbital; Animals; Barbiturates; Female; Foreign-Body Reaction; H | 1972 |
Barbiturate withdrawal syndrome in a passively addicted infant.
Topics: Cesarean Section; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Infant, Newborn; I | 1972 |
Stability of certain drugs of abuse in urine specimens.
Topics: Amphetamine; Azides; Cocaine; Codeine; Drug Stability; Humans; Methadone; Morphine; Pharmaceutical P | 1972 |
Limb compression and renal impairment (crush syndrome) following narcotic and sedative overdose.
Topics: Acute Kidney Injury; Adolescent; Adult; Alcoholic Intoxication; Arm Injuries; Brachial Plexus; Coma; | 1972 |
Addiction to secobarbital and chlordiazepoxide in the rhesus monkey by means of a self-infusion preference procedure.
Topics: Animals; Chlordiazepoxide; Food Preferences; Humans; Injections, Intravenous; Macaca; Male; Secobarb | 1972 |
Drug-induced coma: a cause of crush syndrome and ischemic contracture.
Topics: Acute Kidney Injury; Adult; Coma; Contracture; Female; Heroin; Humans; Ischemia; Male; Muscles; Musc | 1973 |
Accidental intraarterial injection in drug abuse.
Topics: Adult; Arm; Gangrene; Humans; Injections, Intra-Arterial; Male; Pentazocine; Secobarbital; Substance | 1973 |
The acutely swollen hand in the drug user.
Topics: Adolescent; Adult; Bacterial Infections; Barbiturates; Blister; Drainage; Endarteritis; Female; Hand | 1973 |
Separation and quantitation of mixtures of the most commonly abused drugs.
Topics: Amobarbital; Cannabis; Chromatography, Thin Layer; Dextroamphetamine; Ephedrine; Humans; Indicators | 1973 |
Letter: Prescribing hypnotic and anti-anxiety drugs.
Topics: Chlordiazepoxide; Diazepam; Drug Prescriptions; Humans; Hypnotics and Sedatives; Meprobamate; Pentob | 1973 |
The effects of drugs on learning and memory. A review of the literature.
Topics: Aged; Amphetamine; Animals; Cannabis; Child; Chlorpromazine; Dextroamphetamine; Female; Hallucinogen | 1973 |
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chr | 1974 |
Correlation of the "EMIT" urine barbiturate assay with a spectrophotometric serum barbiturate assay in suspected overdose.
Topics: Amobarbital; Barbiturates; Evaluation Studies as Topic; Humans; Methods; Pentobarbital; Phenobarbita | 1974 |
Drug involvement in criminal assaults by adolescents.
Topics: Adolescent; Aggression; Alcoholic Intoxication; Amphetamine; Barbiturates; California; Cannabis; Coc | 1974 |
Outpatient barbiturate withdrawal using phenobarbital.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Amobarbital; Barbiturates; Community Healt | 1972 |
Gangrene due to intra-arterial injection of drugs by drug addicts.
Topics: Adolescent; Adult; Amputation, Surgical; Analgesics; Brachial Artery; Female; Fingers; Gangrene; Hep | 1972 |
Ubiquitous reds: a local perspective on secobarbital abuse.
Topics: Adolescent; Adult; California; Humans; Poisoning; Secobarbital; Socioeconomic Factors; Substance-Rel | 1971 |
Use of hypnotic drugs by hospital patients.
Topics: Adult; Aged; Amobarbital; Antipyrine; Barbiturates; Diphenhydramine; Female; Hospitalization; Humans | 1971 |
Hazards of drug dependency among physicians.
Topics: Humans; Male; Middle Aged; Phenylephrine; Physicians; Secobarbital; Substance Withdrawal Syndrome; S | 1971 |
Acute barbiturate intoxication. Concepts of management.
Topics: Adolescent; Adult; Aged; Alcoholism; Barbiturates; Coma; Diuresis; Female; Gastric Lavage; Gastroint | 1969 |
Volkmann's ischemic contracture after intra-arterial injection of secobarbital.
Topics: Adolescent; Adult; Compartment Syndromes; Fasciotomy; Female; Humans; Injections, Intra-Arterial; Ma | 1970 |
A new method for treatment of barbiturate dependence.
Topics: Barbiturates; Chlordiazepoxide; Diazepam; Heroin; Humans; Meprobamate; Pentobarbital; Phenobarbital; | 1970 |
Value of serum and urine barbiturate tests in monitoring barbiturate withdrawal.
Topics: Barbiturates; Humans; Male; Middle Aged; Secobarbital; Substance-Related Disorders | 1970 |
Effect of intra-arterial injections of barbiturates.
Topics: Adult; Barbiturates; Female; Heparin; Humans; Injections, Intra-Arterial; Male; Secobarbital; Substa | 1970 |
Diagnosis and treatment of drug dependence of the barbiturate type.
Topics: Adult; Barbiturates; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pentobarbital; Psyc | 1968 |
Experimental production of human "blue velvet" and "red devil" lesions.
Topics: Animals; Camphor; Foreign Bodies; Humans; Injections, Intravenous; Meperidine; Microscopy, Polarizat | 1966 |