Page last updated: 2024-08-25

secnidazole and Vaginosis, Bacterial

secnidazole has been researched along with Vaginosis, Bacterial in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.41)18.2507
2000's3 (11.11)29.6817
2010's15 (55.56)24.3611
2020's7 (25.93)2.80

Authors

AuthorsStudies
Muzny, CA; Van Gerwen, OT1
Legendre, D; Muzny, CA; Van Gerwen, OT1
Chavoustie, S; Kaufman, G; Muzny, CA; Van Gerwen, OT1
Boyd, P; Dallal Bashi, YH; Karl Malcolm, R; McCoy, CF; Zhao, X1
Faught, BM; Reyes, S1
Leggit, JC; Saguil, A1
Eckert, LO; Kus, LH; Neal, CM; Peipert, JF1
Abd El Aziz, MA; Abedi, P; Jahanfar, S; Judge, HM; Sharifipour, F1
Adetoro, N; Levy, S; Pentikis, H; Tipping, D1
Arbuckle, J; Carter, BA; Chavoustie, SE; Eder, S; Graves, KJ; Kaufman, G; Lazenby, GB; McMahon, CP; Mena, LA; Muzny, CA; Nyirjesy, P; Pandey, B; Schwebke, JR; Shaw, J; Van Gerwen, OT1
Adetoro, NA; Braun, CJ; Hillier, SL; Morgan, FG; Nyirjesy, P; Schwebke, JR; Waldbaum, AS1
Koltun, W; Morgan, FG; Nyirjesy, P; Schwebke, JR1
Adetoro, N; Darpo, B; Matthews, BG; Pentikis, HS; Xue, H1
Adetoro, N; Pentikis, HS1
Basharat, A; Fahim, A; Khan, DH; Khan, MH; Tariq, N1
Chavoustie, SE; Gersten, JK; Samuel, MJ; Schwebke, JR1
Nyirjesy, P; Schwebke, JR1
Abbas, AM; Badawy, MM; Elghazaly, SM; Hamam, KM; Samy, A; Yakoub Agha, NA1
Adetoro, N; Braun, CJ; Pentikis, HS1
Qian, XD; Wang, FM; Xu, H; Yu, HY1
Acar, J; Brauman, M; De Backer, E; Dubreuil, L; Vaneechoutte, M1
Bohbot, JM; Brauman, M; Fagnen, D; Vicaut, E1
Gómez, G; Núñez, JT1
Ortiz-Ibarra, J; Reyna-Figueroa, J; Villagrana-Zesati, R1
Gillis, JC; Wiseman, LR1
Atalay, C; Göl, K; Oztopçu, C; Sahin, I; Saraçoğlu, F; Türkkani, B1

Reviews

6 review(s) available for secnidazole and Vaginosis, Bacterial

ArticleYear
Secnidazole for Trichomoniasis in Women and Men.
    Sexual medicine reviews, 2022, Volume: 10, Issue:2

    Topics: Female; Humans; Male; Metronidazole; Observational Studies as Topic; Randomized Controlled Trials as Topic; Trichomonas Infections; Trichomonas vaginalis; Vaginosis, Bacterial

2022
Characterization and Treatment of Recurrent Bacterial Vaginosis.
    Journal of women's health (2002), 2019, Volume: 28, Issue:9

    Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Clindamycin; Female; Humans; Metronidazole; Recurrence; Treatment Outcome; Vaginosis, Bacterial

2019
Noncandidal vaginitis: a comprehensive approach to diagnosis and management.
    American journal of obstetrics and gynecology, 2020, Volume: 222, Issue:2

    Topics: Administration, Intravaginal; Administration, Oral; Anti-Infective Agents; Anti-Inflammatory Agents; Atrophic Vaginitis; Candidiasis, Vulvovaginal; Clindamycin; Dehydroepiandrosterone; Diagnosis, Differential; Estrogen Replacement Therapy; Estrogens; Female; Humans; Hydrocortisone; Inflammation; Lichen Planus; Metronidazole; Pemphigoid, Benign Mucous Membrane; Pemphigoid, Bullous; Pemphigus; Tamoxifen; Tinidazole; Trichomonas Vaginitis; Vaginitis; Vaginosis, Bacterial

2020
Secnidazole for treatment of bacterial vaginosis: a systematic review.
    BMC women's health, 2019, 10-21, Volume: 19, Issue:1

    Topics: Administration, Intravaginal; Administration, Oral; Adult; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Humans; Metronidazole; Middle Aged; Recurrence; Treatment Outcome; Vaginosis, Bacterial

2019
Efficacy and safety of single dose of oral secnidazole 2 g in treatment of bacterial vaginosis: A systematic review and meta-analysis.
    European journal of obstetrics, gynecology, and reproductive biology, 2019, Volume: 238

    Topics: Administration, Oral; Antiprotozoal Agents; Female; Humans; Metronidazole; Randomized Controlled Trials as Topic; Vaginosis, Bacterial

2019
Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis.
    Drugs, 1996, Volume: 51, Issue:4

    Topics: Absorption; Clinical Trials as Topic; Drug Interactions; Female; Humans; Male; Metronidazole; Protozoan Infections; Tissue Distribution; Vaginosis, Bacterial

1996

Trials

15 trial(s) available for secnidazole and Vaginosis, Bacterial

ArticleYear
Efficacy of single-dose oral secnidazole for the treatment of trichomoniasis in women co-infected with trichomoniasis and bacterial vaginosis: a post hoc subgroup analysis of phase 3 clinical trial data.
    BMJ open, 2023, 08-07, Volume: 13, Issue:8

    Topics: Coinfection; Female; HIV Infections; Humans; Male; Trichomonas Infections; Vaginosis, Bacterial

2023
An Integrated Efficacy and Safety Analysis of Single-Dose Secnidazole 2 g in the Treatment of Bacterial Vaginosis.
    Reproductive sciences (Thousand Oaks, Calif.), 2020, Volume: 27, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Double-Blind Method; Female; Humans; Metronidazole; Middle Aged; Treatment Outcome; Vaginosis, Bacterial; Young Adult

2020
Efficacy and Safety of Single Oral Dosing of Secnidazole for Trichomoniasis in Women: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled, Delayed-Treatment Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 09-15, Volume: 73, Issue:6

    Topics: Double-Blind Method; Female; Humans; Metronidazole; Treatment Outcome; Trichomonas Infections; Vaginosis, Bacterial

2021
Secnidazole Treatment of Bacterial Vaginosis: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2017, Volume: 130, Issue:2

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal Agents; Black People; Double-Blind Method; Female; Humans; Metronidazole; Middle Aged; Placebos; Treatment Outcome; Vaginosis, Bacterial; White People

2017
A phase-3, double-blind, placebo-controlled study of the effectiveness and safety of single oral doses of secnidazole 2 g for the treatment of women with bacterial vaginosis.
    American journal of obstetrics and gynecology, 2017, Volume: 217, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Antiprotozoal Agents; Candidiasis, Vulvovaginal; Diarrhea; Double-Blind Method; Female; Headache; Humans; Metronidazole; Middle Aged; Nausea; Treatment Outcome; Vaginal Discharge; Vaginosis, Bacterial; Young Adult

2017
Thorough QT/QTc Evaluation of the Cardiac Safety of Secnidazole at Therapeutic and Supratherapeutic Doses in Healthy Individuals.
    Journal of clinical pharmacology, 2018, Volume: 58, Issue:3

    Topics: Adult; Antiprotozoal Agents; Cross-Over Studies; Electrocardiography; Female; Heart Rate; Humans; Long QT Syndrome; Metronidazole; Middle Aged; Vaginosis, Bacterial; Young Adult

2018
Two Phase 1, Open-Label, Single-Dose, Randomized, Crossover Studies to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered Granules of Secnidazole (2 g) in Healthy Female Volunteers Under Different Administration Conditions.
    Clinical pharmacology in drug development, 2018, Volume: 7, Issue:5

    Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Drug Compounding; Fasting; Female; Food; Food-Drug Interactions; Healthy Volunteers; Humans; Metronidazole; Middle Aged; Therapeutic Equivalency; Vaginosis, Bacterial; Young Adult

2018
Treatment for Symptomatic Bacterial Vaginosis: ARandomized Controlled Trial.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2017, Volume: 27, Issue:11

    Topics: Administration, Intravaginal; Administration, Oral; Adult; Anti-Bacterial Agents; Antiprotozoal Agents; Clindamycin; Double-Blind Method; Female; Humans; Metronidazole; Vaginal Creams, Foams, and Jellies; Vaginosis, Bacterial

2017
A Phase 3, Multicenter, Prospective, Open-Label Study to Evaluate the Safety of a Single Dose of Secnidazole 2 g for the Treatment of Women and Postmenarchal Adolescent Girls with Bacterial Vaginosis.
    Journal of women's health (2002), 2018, Volume: 27, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Antiprotozoal Agents; Female; Humans; Metronidazole; Prospective Studies; Treatment Outcome; United States; Vaginal Discharge; Vaginosis, Bacterial; Young Adult

2018
Lack of a Pharmacokinetic Interaction Between SYM-1219 Granules Containing 2 Grams of Secnidazole and a Combined Oral Contraceptive in a Phase 1, Randomized, Open-Label Study in Healthy Female Volunteers.
    Advances in therapy, 2017, Volume: 33, Issue:12

    Topics: Adult; Contraceptives, Oral, Combined; Drug Interactions; Ethinyl Estradiol; Female; Humans; Metronidazole; Middle Aged; Vaginosis, Bacterial

2017
[Efficacy of 5-nitroimidazole derivatives in treatment of bacterial vaginosis].
    Zhonghua yi xue za zhi, 2008, Aug-12, Volume: 88, Issue:31

    Topics: Administration, Intravaginal; Administration, Oral; Adult; Delayed-Action Preparations; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Metronidazole; Nitroimidazoles; Ornidazole; Prospective Studies; Tablets; Tinidazole; Treatment Outcome; Vaginosis, Bacterial; Young Adult

2008
Treatment of bacterial vaginosis: a multicenter, double-blind, double-dummy, randomised phase III study comparing secnidazole and metronidazole.
    Infectious diseases in obstetrics and gynecology, 2010, Volume: 2010

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Chi-Square Distribution; Double-Blind Method; Female; Humans; Metronidazole; Middle Aged; Prospective Studies; Treatment Outcome; Vaginosis, Bacterial

2010
Low-dose secnidazole in the treatment of bacterial vaginosis.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2005, Volume: 88, Issue:3

    Topics: Adult; Antiprotozoal Agents; Female; Humans; Metronidazole; Middle Aged; Papanicolaou Test; Treatment Outcome; Vaginal Smears; Vaginosis, Bacterial

2005
Short-term therapy for mixed vaginal infections.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2006, Volume: 92, Issue:2

    Topics: Administration, Oral; Antifungal Agents; Antiprotozoal Agents; Antitrichomonal Agents; Candidiasis, Vulvovaginal; Drug Therapy, Combination; Female; Fluconazole; Humans; Itraconazole; Metronidazole; Patient Compliance; Tinidazole; Treatment Outcome; Trichomonas Vaginitis; Vaginosis, Bacterial

2006
Treatment of bacterial vaginosis with oral or vaginal ornidazole, secnidazole and metronidazole.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1998, Volume: 62, Issue:1

    Topics: Administration, Intravaginal; Administration, Oral; Anti-Infective Agents; Drug Therapy, Combination; Female; Humans; Metronidazole; Ornidazole; Recurrence; Treatment Outcome; Vaginosis, Bacterial

1998

Other Studies

6 other study(ies) available for secnidazole and Vaginosis, Bacterial

ArticleYear
Secnidazole: a treatment for trichomoniasis in adolescents and adults.
    Expert review of anti-infective therapy, 2022, Volume: 20, Issue:8

    Topics: Adolescent; Adult; Female; Humans; Metronidazole; Nitroimidazoles; Trichomonas Infections; Trichomonas vaginalis; Trichomonas Vaginitis; United States; Vaginosis, Bacterial

2022
Physicochemical considerations in the formulation development of silicone elastomer vaginal rings releasing 5-nitroimidazole drugs for the treatment of bacterial vaginosis.
    International journal of pharmaceutics, 2023, Sep-25, Volume: 644

    Topics: Administration, Intravaginal; Anti-Bacterial Agents; Contraceptive Devices, Female; Delayed-Action Preparations; Female; Humans; Metronidazole; Ornidazole; Silicone Elastomers; Tinidazole; Vaginosis, Bacterial

2023
Secnidazole (Solosec) for Bacterial Vaginosis.
    American family physician, 2019, 08-15, Volume: 100, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Clinical Trials as Topic; Female; Humans; Metronidazole; Treatment Outcome; Vaginosis, Bacterial

2019
Secnidazole: next-generation antimicrobial agent for bacterial vaginosis treatment.
    Future microbiology, 2018, Volume: 13

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Controlled Clinical Trials as Topic; Double-Blind Method; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Metronidazole; Middle Aged; Multicenter Studies as Topic; Trichomonas vaginalis; Trichomonas Vaginitis; United States; Vaginosis, Bacterial; Young Adult

2018
Secnidazole (Solosec) for bacterial vaginosis.
    The Medical letter on drugs and therapeutics, 2018, 03-26, Volume: 60, Issue:1543

    Topics: Anti-Bacterial Agents; Drug Interactions; Female; Humans; Metronidazole; Treatment Outcome; Vaginosis, Bacterial

2018
In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2010, Volume: 16, Issue:5

    Topics: Actinobacteria; Antiprotozoal Agents; Female; Humans; Metronidazole; Microbial Sensitivity Tests; Vaginosis, Bacterial

2010