secalonic-acid has been researched along with Neoplasms* in 1 studies
1 other study(ies) available for secalonic-acid and Neoplasms
| Article | Year |
|---|---|
Secalonic acid D as a selective cytotoxic substance on the cancer cells adapted to nutrient starvation.
Cancer cells adapted to the microenvironment in tumor such as hypoxic and nutrient-starved conditions are now paid much attention as the therapeutic target of cancer. In the course of search for selective cytotoxic substances against cancer cells adapted to nutrient starvation, xanthone derivative of secalonic acid D (1) was isolated from culture extract of marine-derived Penicillium oxalicum. Compound 1 showed cytotoxic activity on the human pancreatic carcinoma PANC-1 cells adapted to glucose-starved conditions with IC Topics: Animals; Antineoplastic Agents; Endoplasmic Reticulum Chaperone BiP; Humans; Mice; Neoplasms; Nutrients; Rats; Tumor Microenvironment; Xanthones | 2020 |