sebacic acid has been researched along with Glioma in 4 studies
sebacic acid : An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " It has been shown previously that implantation of controlled-release polymers impregnated with the nitrosourea carmustine (BCNU) extended the period of survival in rats bearing the 9L glioma compared with similar rats treated with systemically administered BCNU." | 3.69 | Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain. ( Brem, H; Epstein, JI; Olivi, A; Pinn, M; Tamargo, RJ; Weingart, JD; Wharam, M, 1994) |
| "Malignant gliomas have been difficult to treat with chemotherapy." | 2.67 | Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. ( Black, KL; Brem, H; Burger, PC; Ciric, IS; Cozzens, JW; Eller, TW; Friedman, AH; Mahaley, MS; Schold, SC; Vick, NA, 1991) |
| "Animals with brain tumors treated with 4HC had a median survival span of 77 days compared to the median survival of 21 days in BCNU-treated animals and median survival of 14 days in untreated animals." | 1.29 | Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas. ( Brem, H; Buahin, KG; Colvin, OM; Domb, A; Epstein, JI; Judy, KD; Olivi, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Judy, KD | 1 |
| Olivi, A | 2 |
| Buahin, KG | 1 |
| Domb, A | 1 |
| Epstein, JI | 2 |
| Colvin, OM | 1 |
| Brem, H | 3 |
| Tamargo, RJ | 1 |
| Pinn, M | 1 |
| Weingart, JD | 1 |
| Wharam, M | 1 |
| Yuan, X | 1 |
| Dillehay, LE | 1 |
| Williams, JR | 1 |
| Shastri, VR | 1 |
| Williams, JA | 1 |
| Mahaley, MS | 1 |
| Vick, NA | 1 |
| Black, KL | 1 |
| Schold, SC | 1 |
| Burger, PC | 1 |
| Friedman, AH | 1 |
| Ciric, IS | 1 |
| Eller, TW | 1 |
| Cozzens, JW | 1 |
1 trial available for sebacic acid and Glioma
| Article | Year |
|---|---|
Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas.
Topics: Brain Neoplasms; Carmustine; Decanoic Acids; Dicarboxylic Acids; Drug Combinations; Drug Implants; F | 1991 |
3 other studies available for sebacic acid and Glioma
| Article | Year |
|---|---|
Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cyclophosphamide; Decanoic Acids; Delay | 1995 |
Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain.
Topics: Animals; Brain Edema; Brain Neoplasms; Carmustine; Decanoic Acids; Dicarboxylic Acids; Drug Combinat | 1994 |
IUdR polymers for combined continuous low-dose rate and high-dose rate sensitization of experimental human malignant gliomas.
Topics: Animals; Biocompatible Materials; Brain Neoplasms; Cell Line; Decanoic Acids; Dicarboxylic Acids; Do | 2001 |