sdz-280-446 and Carcinoma

sdz-280-446 has been researched along with Carcinoma* in 1 studies

Other Studies

1 other study(ies) available for sdz-280-446 and Carcinoma

Article	Year
Differential expression of translation-associated genes in benign and malignant human breast tumours. British journal of cancer, 1992, Volume: 65, Issue:1 The human gene sequences encoding the translation-associated functions of alpha-subunit of elongation factor 1 (EF-1 alpha) and the ubiquitin carboxyl extension protein (HUBCEP80) have been isolated by differential cDNA screening, and found to have significantly higher levels of expression in fibroadenomas (benign) compared with carcinomas (malignant) of the breast. These data parallel our previous findings that the acidic ribosomal phosphoprotein P2 also has higher expression levels in the benign breast tumours (Sharp et al., 1990). In situ hybridisation has shown these genes to be expressed predominantly in the epithelium of breast tumours. Topics: Adenofibroma; Amino Acid Sequence; Base Sequence; Blotting, Northern; Breast Neoplasms; Carcinoma; Cloning, Molecular; DNA Probes; DNA, Neoplasm; Female; Gene Library; Humans; Molecular Sequence Data; Peptides, Cyclic; Poly A; Protein Biosynthesis; RNA; RNA Probes; RNA, Messenger	1992

Article

Year

Differential expression of translation-associated genes in benign and malignant human breast tumours.

British journal of cancer, 1992, Volume: 65, Issue:1

The human gene sequences encoding the translation-associated functions of alpha-subunit of elongation factor 1 (EF-1 alpha) and the ubiquitin carboxyl extension protein (HUBCEP80) have been isolated by differential cDNA screening, and found to have significantly higher levels of expression in fibroadenomas (benign) compared with carcinomas (malignant) of the breast. These data parallel our previous findings that the acidic ribosomal phosphoprotein P2 also has higher expression levels in the benign breast tumours (Sharp et al., 1990). In situ hybridisation has shown these genes to be expressed predominantly in the epithelium of breast tumours.

Topics: Adenofibroma; Amino Acid Sequence; Base Sequence; Blotting, Northern; Breast Neoplasms; Carcinoma; Cloning, Molecular; DNA Probes; DNA, Neoplasm; Female; Gene Library; Humans; Molecular Sequence Data; Peptides, Cyclic; Poly A; Protein Biosynthesis; RNA; RNA Probes; RNA, Messenger

1992