Page last updated: 2024-09-05

scutellarin and Infarction, Middle Cerebral Artery

scutellarin has been researched along with Infarction, Middle Cerebral Artery in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (21.05)29.6817
2010's11 (57.89)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Li, D; Li, S; Li, Y1
Hongyun, H; Liqiang, Y; Pengyue, Z; Tao, G; Yihao, D1
Chen, Z; Dong, L; Jiang, Q; Li, X; Wang, Y; Wu, X; Zhang, G; Zhen, Y1
Chen, XL; Liu, JX; Liu, Y; Qian, YH; Song, TS; Zhao, JJ1
Lin, LL; Liu, AJ; Liu, JG; Qin, LP; Su, DF; Yu, XH1
Deng, X; Liu, X; Liu, Y; Shi, J; Wang, C; Yan, X; Zhang, Y1
Chen, HL; Han, H; Jia, WJ; Li, F; Li, HE; Li, JJ; Wu, CY; Yuan, Y; Zhang, XL1
Fan, G; Liang, W; Liu, G; Tang, G; Wang, Y; Wang, Z; Xu, W; Zhao, M1
Chen, LM; Gao, HM; Gong, LL; Liang, RX; Liu, XQ; Ma, XJ; Wang, L; Wang, ZM; Yin, XJ1
Ling, EA; Rangarajan, P; Wu, C; Yuan, Y; Zha, H1
Kan, EM; Ling, EA; Rangarajan, P; Wu, C; Wu, Y; Yuan, Y1
Fang, M; Ling, EA; Lu, J; Rangarajan, P; Wang, H; Wu, C; Wu, Y; Yuan, Y1
Han, J; Ma, X; Pan, Q; Ren, H; Wang, W; Zheng, C; Zheng, Q; Zhou, M1
Chen, T; Gong, Z; Hu, J; Lan, Y; Li, Y; Liu, T; Lu, Y; Mi, L; Wang, A; Wang, Y; Yang, W; Zheng, J1
Hu, XM; Wang, LX; Xu, SQ; Zeng, FD; Zhang, HF1
Cheng, C; Liu, Q; Lu, J; Luo, G; Wang, Y; Yang, P; Zhao, X1
Gao, XM; Guo, H; Hu, LM; Kang, LY; Li, H; Liu, Y; Shi, F; Wang, SX; Wang, YL1
Fu, Y; Li, NG; Qian, L; Shen, M; Shi, Q; Tang, H; Tang, Y; Zhang, L1
Hu, XM; Zeng, FD; Zhou, MM1

Other Studies

19 other study(ies) available for scutellarin and Infarction, Middle Cerebral Artery

ArticleYear
Breviscapine Alleviates Cognitive Impairments Induced by Transient Cerebral Ischemia/Reperfusion through Its Anti-Inflammatory and Anti-Oxidant Properties in a Rat Model.
    ACS chemical neuroscience, 2020, 12-16, Volume: 11, Issue:24

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Brain Ischemia; China; Cognitive Dysfunction; Flavonoids; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury

2020
Breviscapine confers a neuroprotective efficacy against transient focal cerebral ischemia by attenuating neuronal and astrocytic autophagy in the penumbra.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Animals; Astrocytes; Autophagy; Beclin-1; Brain; Brain Ischemia; Disease Models, Animal; Flavonoids; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Neurons; Neuroprotection; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke

2017
Vitexin protects brain against ischemia/reperfusion injury via modulating mitogen-activated protein kinase and apoptosis signaling in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Mar-15, Volume: 22, Issue:3

    Topics: Animals; Apigenin; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Infarction, Middle Cerebral Artery; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mice; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury

2015
Breviscapine improves functions of spatial learning and memory of focal cerebral ischemia rats.
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2009, Volume: 32, Issue:4

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Erigeron; Flavonoids; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Maze Learning; Memory; Neuroprotective Agents; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Spatial Behavior

2009
Protective effects of scutellarin and breviscapine on brain and heart ischemia in rats.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:3

    Topics: Animals; Apigenin; Apoptosis; Brain Ischemia; Cardiotonic Agents; Dose-Response Relationship, Drug; Drug Combinations; Flavonoids; Glucuronates; Infarction, Middle Cerebral Artery; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Toxicity Tests, Acute

2007
Scutellarin Alleviates Ischemic Brain Injury in the Acute Phase by Affecting the Activity of Neurotransmitters in Neurons.
    Molecules (Basel, Switzerland), 2023, Apr-04, Volume: 28, Issue:7

    Topics: Animals; Brain Injuries; Brain Ischemia; Infarction, Middle Cerebral Artery; Molecular Docking Simulation; Neurons; Neurotransmitter Agents; Rats; Reperfusion Injury; Stroke

2023
Scutellarin Exerts Anti-Inflammatory Effects in Activated Microglia/Brain Macrophage in Cerebral Ischemia and in Activated BV-2 Microglia Through Regulation of MAPKs Signaling Pathway.
    Neuromolecular medicine, 2020, Volume: 22, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apigenin; Cerebral Cortex; Gene Expression Regulation; Glucuronates; Imidazoles; Infarction, Middle Cerebral Artery; Inflammation Mediators; Macrophage Activation; Male; MAP Kinase Signaling System; Mice; Microglia; Nerve Tissue Proteins; Nitric Oxide Synthase Type II; Protein Kinases; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2020
PK-PD Correlation of Erigeron Breviscapus Injection in the Treatment of Cerebral Ischemia-Reperfusion Injury Model Rats.
    Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:2

    Topics: Animals; Apigenin; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Erigeron; Glucuronates; Infarction, Middle Cerebral Artery; Injections, Intravenous; Male; Molecular Structure; Phytotherapy; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2021
[Protective effect and mechanism of scutellarin ethyl ester on focal cerebral ischemia induced by ligation of middle cerebral artery in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:7

    Topics: Animals; Apigenin; Brain Ischemia; Glucuronates; Infarction, Middle Cerebral Artery; Male; Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2017
Anti-inflammatory effects of Edaravone and Scutellarin in activated microglia in experimentally induced ischemia injury in rats and in BV-2 microglia.
    BMC neuroscience, 2014, Nov-22, Volume: 15

    Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Apigenin; Brain; Brain Ischemia; Cell Count; Cell Line; Cell Survival; Cytokines; Disease Models, Animal; Edaravone; Glucuronates; Infarction, Middle Cerebral Artery; Lipopolysaccharides; Male; Microglia; Nitric Oxide; Nitric Oxide Synthase Type II; Random Allocation; Rats, Sprague-Dawley; Reactive Oxygen Species

2014
Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia.
    Journal of neuroinflammation, 2015, Jan-20, Volume: 12

    Topics: Actins; Animals; Apigenin; Cell Adhesion; Cell Line, Transformed; Cell Movement; Cerebrum; Disease Models, Animal; Dose-Response Relationship, Drug; Glucuronates; Infarction, Middle Cerebral Artery; Lipopolysaccharides; Male; Microglia; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptors, Notch; rho GTP-Binding Proteins; Signal Transduction; Tumor Necrosis Factor-alpha

2015
Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats.
    BMC neuroscience, 2015, Nov-25, Volume: 16

    Topics: Animals; Anti-Inflammatory Agents; Apigenin; Astrocytes; Brain Ischemia; Cell Line; Cell Survival; Cerebral Cortex; Disease Models, Animal; Gliosis; Glucuronates; Infarction, Middle Cerebral Artery; Male; Mice; Microglia; Neuroprotective Agents; Rats, Sprague-Dawley

2015
Neuroprotective Effect of Scutellarin on Ischemic Cerebral Injury by Down-Regulating the Expression of Angiotensin-Converting Enzyme and AT1 Receptor.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Apigenin; Brain; Brain Ischemia; Disease Models, Animal; Down-Regulation; Glucuronates; Infarction, Middle Cerebral Artery; Interleukin-1beta; Interleukin-6; Neuroprotective Agents; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tumor Necrosis Factor-alpha

2016
Pharmacokinetic Comparison of Scutellarin and Paeoniflorin in Sham-Operated and Middle Cerebral Artery Occlusion Ischemia and Reperfusion Injury Rats after Intravenous Administration of Xin-Shao Formula.
    Molecules (Basel, Switzerland), 2016, Sep-07, Volume: 21, Issue:9

    Topics: Animals; Apigenin; Disease Models, Animal; Glucosides; Glucuronates; Infarction, Middle Cerebral Artery; Male; Medicine, Chinese Traditional; Monoterpenes; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke

2016
Protective effects of scutellarin against cerebral ischemia in rats: evidence for inhibition of the apoptosis-inducing factor pathway.
    Planta medica, 2009, Volume: 75, Issue:2

    Topics: Animals; Apigenin; Apoptosis; Apoptosis Inducing Factor; Biological Transport; Brain; Brain Ischemia; Cell Nucleus; DNA Fragmentation; Erigeron; Glucuronates; Infarction, Middle Cerebral Artery; Male; Mitochondria; NAD; Neuroprotective Agents; Phytotherapy; Plant Extracts; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley

2009
PEG-scutellarin prodrugs: synthesis, water solubility and protective effect on cerebral ischemia/reperfusion injury.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:5

    Topics: Animals; Apigenin; Disease Models, Animal; Drug Evaluation, Preclinical; Glucuronates; Infarction, Middle Cerebral Artery; Molecular Structure; Molecular Weight; Polyethylene Glycols; Prodrugs; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Solubility; Stereoisomerism; Water

2010
Neuroprotective effects of scutellarin against hypoxic-ischemic-induced cerebral injury via augmentation of antioxidant defense capacity.
    The Chinese journal of physiology, 2011, Dec-31, Volume: 54, Issue:6

    Topics: Animals; Antioxidants; Apigenin; Brain Infarction; Cerebral Cortex; Drugs, Chinese Herbal; Glucuronates; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Oxidative Stress; Primary Cell Culture; Rats; Rats, Wistar; Reactive Oxygen Species

2011
Synthesis and protective effect of scutellarein on focal cerebral ischemia/reperfusion in rats.
    Molecules (Basel, Switzerland), 2012, Sep-06, Volume: 17, Issue:9

    Topics: Animals; Apigenin; Brain Ischemia; Glucuronates; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Rats; Reperfusion Injury

2012
Neuroprotective effects of scutellarin on rat neuronal damage induced by cerebral ischemia/reperfusion.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:12

    Topics: Animals; Apigenin; Blood-Brain Barrier; Brain; Brain Ischemia; Erigeron; Fibroblast Growth Factor 2; Glucuronates; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vascular Endothelial Growth Factor A

2005