scutellarin has been researched along with Brain Ischemia in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 18 (56.25) | 24.3611 |
| 2020's | 9 (28.13) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, HD; Jiang, MZ; Lai, Y; Lan, H; Li, X; Yang, WQ; Zhao, YY | 1 |
| Li, D; Li, S; Li, Y | 1 |
| Hongyun, H; Liqiang, Y; Pengyue, Z; Tao, G; Yihao, D | 1 |
| Guan, Y; Guo, C; Wang, S; Wei, G; Wen, A; Weng, Y; Xi, M; Yin, Y; Zhu, Y | 1 |
| Cai, J; Gu, J; Tian, LH; Yu, L; Zhao, LZ | 1 |
| Chen, Z; Dong, L; Jiang, Q; Li, X; Wang, Y; Wu, X; Zhang, G; Zhen, Y | 1 |
| Lei, H; Liao, W; Liu, H; Wei, L | 1 |
| Chen, XL; Liu, JX; Liu, Y; Qian, YH; Song, TS; Zhao, JJ | 1 |
| Lin, LL; Liu, AJ; Liu, JG; Qin, LP; Su, DF; Yu, XH | 1 |
| Bai, N; Huo, Q; Vijayalakshmi, A; Wang, J; Zhang, X; Zhang, Y; Zhang, Z; Zhao, J | 1 |
| Deng, X; Liu, X; Liu, Y; Shi, J; Wang, C; Yan, X; Zhang, Y | 1 |
| Chen, HL; Duan, ZD; Jia, QY; Li, JJ; Liu, TT; Qi, Z; Wu, CY; Yang, L; Yuan, Y; Zhang, XL; Zheng, LY | 1 |
| Chen, HL; Jia, QY; Liu, TT; Qi, Z; Wu, CY; Yang, L; Yuan, Y; Zhang, XL; Zheng, LY | 1 |
| Jia, W; Wu, C; Yang, L; Yuan, Y | 1 |
| Ding, M; Fan, L; Ge, W; Gu, S; Meng, X; Sun, X; Wang, F; Wang, Z; Xie, X; Xing, X; Zhang, W | 1 |
| Fu, CG; Guo, SY; Liu, SY; Liu, XK; Meng, ZQ; Ni, MW; Wu, JR; Zhou, W; Zhu, YL | 1 |
| Dong, ZX; Fang, F; Gu, T; Li, HM; Li, NG; Lu, YT; Shi, ZH; Sun, Y; Tang, YP; Wu, WY; Xue, X; Zhong, Y | 1 |
| Ho, PC; Liu, S | 1 |
| Chen, LM; Gao, HM; Gong, LL; Liang, RX; Liu, XQ; Ma, XJ; Wang, L; Wang, ZM; Yin, XJ | 1 |
| Chledzik, S; Matuszek, K; Nazaruk, J; Strawa, J | 1 |
| Adah, D; Chai, L; Guo, H; Hu, LM; Li, H; Liu, Y; Shi, F; Wang, S; Wang, YL | 1 |
| Duan, JA; Guo, J; Li, N; Shang, E; Shi, Q; Tang, H; Tang, Y | 1 |
| Ling, EA; Rangarajan, P; Wu, C; Yuan, Y; Zha, H | 1 |
| Dong, Z; Duan, JA; Gu, T; Li, NG; Li, W; Lin, H; Shen, M; Shi, Q; Tang, H; Tang, Y; Zhang, P; Zhang, W | 1 |
| Fang, M; Ling, EA; Lu, J; Rangarajan, P; Wang, H; Wu, C; Wu, Y; Yuan, Y | 1 |
| Han, J; Ma, X; Pan, Q; Ren, H; Wang, W; Zheng, C; Zheng, Q; Zhou, M | 1 |
| Fang, M; Ling, EA; Wu, CY; Yuan, Y | 1 |
| Fang, M; Li, HE; Ling, EA; Lu, J; Wu, CY; Yuan, Y; Zhao, M | 1 |
| Fang, M; Karthikeyan, A; Ling, EA; Wu, CY; Yuan, Y | 1 |
| Hu, XM; Wang, LX; Xu, SQ; Zeng, FD; Zhang, HF | 1 |
| Fu, Y; Li, NG; Qian, L; Shen, M; Shi, Q; Tang, H; Tang, Y; Zhang, L | 1 |
| Hu, XM; Zeng, FD; Zhou, MM | 1 |
4 review(s) available for scutellarin and Brain Ischemia
| Article | Year |
|---|---|
[Breviscapine listed on progress of new varieties and dosage form research].
Topics: Biomedical Research; Brain Ischemia; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavonoids; Humans | 2014 |
Pharmacological Effects of Scutellarin, An Active Component of Genus Scutellaria and Erigeron: A Systematic Review.
Topics: Alzheimer Disease; Apigenin; Brain Ischemia; Databases, Bibliographic; Diabetic Angiopathies; Erigeron; Gastritis; Glucuronates; Helicobacter Infections; Helicobacter pylori; Humans; Myocardial Ischemia; Phytotherapy; Scutellaria | 2018 |
Scutellarin as a Potential Therapeutic Agent for Microglia-Mediated Neuroinflammation in Cerebral Ischemia.
Topics: Apigenin; Brain Ischemia; Drugs, Chinese Herbal; Glucuronates; Humans; Inflammation; Microglia; Signal Transduction | 2016 |
Scutellarin Attenuates Microglia-Mediated Neuroinflammation and Promotes Astrogliosis in Cerebral Ischemia - A Therapeutic Consideration.
Topics: Apigenin; Astrocytes; Brain Ischemia; Glucuronates; Humans; Microglia | 2017 |
28 other study(ies) available for scutellarin and Brain Ischemia
| Article | Year |
|---|---|
Effects of breviscapine on cerebral ischemia-reperfusion injury and intestinal flora imbalance by regulating the TLR4/MyD88/NF-κB signaling pathway in rats.
Topics: Animals; Brain Ischemia; Cytochrome P-450 CYP3A; Drugs, Chinese Herbal; Erigeron; Flavonoids; Gastrointestinal Microbiome; Molecular Docking Simulation; Myeloid Differentiation Factor 88; NF-kappa B; Nimodipine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; RNA, Ribosomal, 16S; Signal Transduction; Toll-Like Receptor 4 | 2023 |
Breviscapine Alleviates Cognitive Impairments Induced by Transient Cerebral Ischemia/Reperfusion through Its Anti-Inflammatory and Anti-Oxidant Properties in a Rat Model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Brain Ischemia; China; Cognitive Dysfunction; Flavonoids; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury | 2020 |
Breviscapine confers a neuroprotective efficacy against transient focal cerebral ischemia by attenuating neuronal and astrocytic autophagy in the penumbra.
Topics: Animals; Astrocytes; Autophagy; Beclin-1; Brain; Brain Ischemia; Disease Models, Animal; Flavonoids; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Neurons; Neuroprotection; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke | 2017 |
Therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemia/reperfusion injury in rats.
Topics: Animals; Brain Ischemia; Erigeron; Flavonoids; Male; Molecular Structure; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2014 |
Vitexin protects brain against ischemia/reperfusion injury via modulating mitogen-activated protein kinase and apoptosis signaling in mice.
Topics: Animals; Apigenin; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Infarction, Middle Cerebral Artery; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mice; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury | 2015 |
[Effects of Dengzhan Xixin on blood-brain barrier permeability and metabolites after cerebral ischemia-reperfusion injuries].
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Flavonoids; Male; Permeability; Rats; Rats, Wistar; Reperfusion Injury; Water | 2009 |
Breviscapine improves functions of spatial learning and memory of focal cerebral ischemia rats.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Erigeron; Flavonoids; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Maze Learning; Memory; Neuroprotective Agents; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Spatial Behavior | 2009 |
Protective effects of scutellarin and breviscapine on brain and heart ischemia in rats.
Topics: Animals; Apigenin; Apoptosis; Brain Ischemia; Cardiotonic Agents; Dose-Response Relationship, Drug; Drug Combinations; Flavonoids; Glucuronates; Infarction, Middle Cerebral Artery; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Toxicity Tests, Acute | 2007 |
Scutellarin alleviates cerebral ischemia/reperfusion by suppressing oxidative stress and inflammatory responses via MAPK/NF-κB pathways in rats.
Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; Brain Ischemia; NF-kappa B; Oxidative Stress; Rats; Reperfusion; Reperfusion Injury | 2022 |
Scutellarin Alleviates Ischemic Brain Injury in the Acute Phase by Affecting the Activity of Neurotransmitters in Neurons.
Topics: Animals; Brain Injuries; Brain Ischemia; Infarction, Middle Cerebral Artery; Molecular Docking Simulation; Neurons; Neurotransmitter Agents; Rats; Reperfusion Injury; Stroke | 2023 |
Scutellarin Acts via MAPKs Pathway to Promote M2 Polarization of Microglial Cells.
Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Interleukin-10; Interleukin-4; Lipopolysaccharides; Microglia; Rats | 2023 |
Network pharmacology to explore the mechanism of scutellarin in the treatment of brain ischaemia and experimental verification of JAK2/STAT3 signalling pathway.
Topics: Animals; Brain Injuries; Brain Ischemia; Culture Media, Conditioned; Janus Kinase 2; Lipopolysaccharides; Network Pharmacology; Rats | 2023 |
Scutellarin attenuates microglia activation in experimentally induced hypoxia-ischemia brain damage by down-regulating miRNA-7036a.
Topics: Brain; Brain Ischemia; Glucuronates; Humans; Hypoxia-Ischemia, Brain; Ischemia; Microglia; MicroRNAs | 2023 |
Scutellarin attenuates oxidative stress and neuroinflammation in cerebral ischemia/reperfusion injury through PI3K/Akt-mediated Nrf2 signaling pathways.
Topics: Animals; Antioxidants; Brain Ischemia; Humans; Neuroinflammatory Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reperfusion Injury; Signal Transduction | 2023 |
Revealing the Common Mechanisms of Scutellarin in Angina Pectoris and Ischemic Stroke Treatment via a Network Pharmacology Approach.
Topics: Angina Pectoris; Apigenin; Brain Ischemia; Glucuronates; Humans; Ischemic Stroke; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases | 2021 |
Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative.
Topics: Animals; Antioxidants; Apigenin; Biphenyl Compounds; Brain Ischemia; Cerebrovascular Disorders; Chromans; Erigeron; Fibrinolytic Agents; Free Radical Scavengers; Glucuronates; Humans; Male; Picrates; Rabbits; Solubility | 2017 |
Intranasal administration of brain-targeted HP-β-CD/chitosan nanoparticles for delivery of scutellarin, a compound with protective effect in cerebral ischaemia.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Intranasal; Animals; Apigenin; Biological Availability; Brain; Brain Ischemia; Chemistry, Pharmaceutical; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Glucuronates; Half-Life; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Solubility; Tissue Distribution | 2017 |
[Protective effect and mechanism of scutellarin ethyl ester on focal cerebral ischemia induced by ligation of middle cerebral artery in rats].
Topics: Animals; Apigenin; Brain Ischemia; Glucuronates; Infarction, Middle Cerebral Artery; Male; Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2017 |
Scutellarin and caffeic acid ester fraction, active components of Dengzhanxixin injection, upregulate neurotrophins synthesis and release in hypoxia/reoxygenation rat astrocytes.
Topics: Animals; Apigenin; Astrocytes; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Caffeic Acids; Cell Line, Tumor; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Drugs, Chinese Herbal; Glial Cell Line-Derived Neurotrophic Factor; Glucuronates; Hypoxia; Male; Mice; Nerve Growth Factor; Oncogene Protein v-akt; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Up-Regulation | 2013 |
Neuroprotective effects of scutellarin and scutellarein on repeatedly cerebral ischemia-reperfusion in rats.
Topics: Amino Acids; Animals; Antioxidants; Apigenin; Brain; Brain Injuries; Brain Ischemia; CA1 Region, Hippocampal; Calcium; Calcium-Transporting ATPases; Glucuronates; Learning; Male; Memory; Neuroprotective Agents; Nimodipine; Potassium; Rats; Rats, Wistar; Reperfusion Injury; Sodium; Sodium-Potassium-Exchanging ATPase | 2014 |
Anti-inflammatory effects of Edaravone and Scutellarin in activated microglia in experimentally induced ischemia injury in rats and in BV-2 microglia.
Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Apigenin; Brain; Brain Ischemia; Cell Count; Cell Line; Cell Survival; Cytokines; Disease Models, Animal; Edaravone; Glucuronates; Infarction, Middle Cerebral Artery; Lipopolysaccharides; Male; Microglia; Nitric Oxide; Nitric Oxide Synthase Type II; Random Allocation; Rats, Sprague-Dawley; Reactive Oxygen Species | 2014 |
Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult.
Topics: Animals; Apigenin; Brain Ischemia; Drugs, Chinese Herbal; Glucuronates; Male; Metabolome; Metabolomics; Neuroprotective Agents; Rats; Rats, Wistar | 2015 |
Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats.
Topics: Animals; Anti-Inflammatory Agents; Apigenin; Astrocytes; Brain Ischemia; Cell Line; Cell Survival; Cerebral Cortex; Disease Models, Animal; Gliosis; Glucuronates; Infarction, Middle Cerebral Artery; Male; Mice; Microglia; Neuroprotective Agents; Rats, Sprague-Dawley | 2015 |
Neuroprotective Effect of Scutellarin on Ischemic Cerebral Injury by Down-Regulating the Expression of Angiotensin-Converting Enzyme and AT1 Receptor.
Topics: Animals; Apigenin; Brain; Brain Ischemia; Disease Models, Animal; Down-Regulation; Glucuronates; Infarction, Middle Cerebral Artery; Interleukin-1beta; Interleukin-6; Neuroprotective Agents; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tumor Necrosis Factor-alpha | 2016 |
Scutellarin promotes microglia-mediated astrogliosis coupled with improved behavioral function in cerebral ischemia.
Topics: Animals; Apigenin; Brain Ischemia; Cell Movement; Cells, Cultured; Cognition; Gliosis; Glucuronates; Male; Microglia; Rats; Rats, Sprague-Dawley | 2016 |
Protective effects of scutellarin against cerebral ischemia in rats: evidence for inhibition of the apoptosis-inducing factor pathway.
Topics: Animals; Apigenin; Apoptosis; Apoptosis Inducing Factor; Biological Transport; Brain; Brain Ischemia; Cell Nucleus; DNA Fragmentation; Erigeron; Glucuronates; Infarction, Middle Cerebral Artery; Male; Mitochondria; NAD; Neuroprotective Agents; Phytotherapy; Plant Extracts; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley | 2009 |
Synthesis and protective effect of scutellarein on focal cerebral ischemia/reperfusion in rats.
Topics: Animals; Apigenin; Brain Ischemia; Glucuronates; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Rats; Reperfusion Injury | 2012 |
Neuroprotective effects of scutellarin on rat neuronal damage induced by cerebral ischemia/reperfusion.
Topics: Animals; Apigenin; Blood-Brain Barrier; Brain; Brain Ischemia; Erigeron; Fibroblast Growth Factor 2; Glucuronates; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vascular Endothelial Growth Factor A | 2005 |