Page last updated: 2024-11-04

scriptaid and Disease Models, Animal

scriptaid has been researched along with Disease Models, Animal in 9 studies

scriptide: provokes translocation of GLUT4 to increase glucose uptake; structure in first source

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"To investigate the role of Scriptaid in reducing brain injury after intracerebral hemorrhage (ICH) in mice."7.88Histone Deacetylase Inhibitor Scriptaid Alleviated Neurological Dysfunction after Experimental Intracerebral Hemorrhage in Mice. ( Gu, Y; Jiang, H; Lei, Y; Ni, W; Su, J; Yang, H; Zhou, L, 2018)
"SAHA, Valproic Acid, Scriptaid, MS275 and LBH589 were combined with Delta24-RGD in fourteen distinct GSCs."5.42The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells. ( Berghauser Pont, LM; de Vrij, J; Dirven, CM; Kaufmann, JK; Kleijn, A; Kloezeman, JJ; Lamfers, ML; Leenstra, S; van den Bossche, W, 2015)
"To investigate the role of Scriptaid in reducing brain injury after intracerebral hemorrhage (ICH) in mice."3.88Histone Deacetylase Inhibitor Scriptaid Alleviated Neurological Dysfunction after Experimental Intracerebral Hemorrhage in Mice. ( Gu, Y; Jiang, H; Lei, Y; Ni, W; Su, J; Yang, H; Zhou, L, 2018)
"These findings indicate that Scriptaid is safe and can alleviate brain injury after ICH, thereby providing a foundation for the pharmacological action of Scriptaid in the treatment of brain injury after ICH."1.56Pharmacokinetics and Acute Toxicity of a Histone Deacetylase Inhibitor, Scriptaid, and its Neuroprotective Effects in Mice After Intracranial Hemorrhage. ( Gao, X; Gu, Y; Jiang, H; Lei, Y; Ni, W; Su, J; Yang, H, 2020)
"SAHA, Valproic Acid, Scriptaid, MS275 and LBH589 were combined with Delta24-RGD in fourteen distinct GSCs."1.42The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells. ( Berghauser Pont, LM; de Vrij, J; Dirven, CM; Kaufmann, JK; Kleijn, A; Kloezeman, JJ; Lamfers, ML; Leenstra, S; van den Bossche, W, 2015)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's5 (55.56)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Yang, H3
Gao, X2
Su, J3
Jiang, H3
Lei, Y3
Ni, W3
Gu, Y3
Wei, P1
Li, S1
Zhou, L2
Berghauser Pont, LM1
Kleijn, A1
Kloezeman, JJ1
van den Bossche, W1
Kaufmann, JK1
de Vrij, J1
Leenstra, S1
Dirven, CM1
Lamfers, ML1
Qing, H2
Aono, J1
Findeisen, HM2
Jones, KL2
Heywood, EB2
Bruemmer, D2
Gizard, F1
Zhao, Y1
Cohn, D1
Wang, G1
Jiang, X1
Pu, H1
Zhang, W1
An, C1
Hu, X1
Liou, AK1
Leak, RK1
Gao, Y1
Chen, J1
Corcoran, LJ1
Mitchison, TJ1
Liu, Q1

Other Studies

9 other studies available for scriptaid and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Pharmacokinetics and Acute Toxicity of a Histone Deacetylase Inhibitor, Scriptaid, and its Neuroprotective Effects in Mice After Intracranial Hemorrhage.
    CNS & neurological disorders drug targets, 2020, Volume: 19, Issue:1

    Topics: Animals; Brain; Disease Models, Animal; Female; Histone Deacetylase Inhibitors; Hydroxylamines; Intr

2020
HDAC inhibition reduces white matter injury after intracerebral hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021, Volume: 41, Issue:5

    Topics: Animals; Blood Coagulation Factors; Case-Control Studies; Cerebral Hemorrhage; Coculture Techniques;

2021
Histone Deacetylase Inhibitor Scriptaid Alleviated Neurological Dysfunction after Experimental Intracerebral Hemorrhage in Mice.
    Behavioural neurology, 2018, Volume: 2018

    Topics: Animals; Basal Ganglia; Brain; Brain Edema; Brain Injuries; Cerebral Hemorrhage; Disease Models, Ani

2018
The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adenoviridae; Animals; Apoptosis; Astrocytes; Autophagy; Brain Neoplasms; Cell Survival; Disease Mod

2015
Differential Regulation of Telomerase Reverse Transcriptase Promoter Activation and Protein Degradation by Histone Deacetylase Inhibition.
    Journal of cellular physiology, 2016, Volume: 231, Issue:6

    Topics: Animals; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Gene Expression Regulation; H

2016
Epigenetic regulation of vascular smooth muscle cell proliferation and neointima formation by histone deacetylase inhibition.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:4

    Topics: Acetylation; Animals; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Chromati

2011
Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway : scriptaid protects against TBI via AKT.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2013, Volume: 10, Issue:1

    Topics: Animals; Blotting, Western; Brain Injuries; Disease Models, Animal; Fluorescent Antibody Technique;

2013
A novel action of histone deacetylase inhibitors in a protein aggresome disease model.
    Current biology : CB, 2004, Mar-23, Volume: 14, Issue:6

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Fractionation; Chlorocebus aethiops; COS Cells; Disease

2004